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DNA pattern matching is essential for many widely used bioinformatics applications. Disease diagnosis is one of these applications, since analyzing changes in DNA sequences can increase our understanding of possible genetic diseases. The…

Hardware Architecture · Computer Science 2022-06-01 Jinane Bazzi , Jana Sweidan , Mohammed E. Fouda , Rouwaida Kanj , Ahmed M. Eltawil

The data encoding circuits used in quantum support vector machine (QSVM) kernels play a crucial role in their classification accuracy. However, manually designing these circuits poses significant challenges in terms of time and performance.…

Quantum Physics · Physics 2026-05-22 Floyd M. Creevey , Jamie A. Heredge , Martin E. Sevior , Lloyd C. L. Hollenberg

Asynchronous algorithms have attracted much attention recently due to the crucial demands on solving large-scale optimization problems. However, the accelerated versions of asynchronous algorithms are rarely studied. In this paper, we…

Optimization and Control · Mathematics 2018-02-28 Cong Fang , Yameng Huang , Zhouchen Lin

Neural networks have demonstrated their outstanding performance in a wide range of tasks. Specifically recurrent architectures based on long-short term memory (LSTM) cells have manifested excellent capability to model time dependencies in…

Machine Learning · Computer Science 2021-11-09 Martin Ferianc , Zhiqiang Que , Hongxiang Fan , Wayne Luk , Miguel Rodrigues

Approximate Nearest Neighbor Search (ANNS) is a core primitive in modern AI systems, and graph-based methods currently offer the best accuracy-efficiency trade-off at scale. The workload is fundamentally memory-bound: graph traversal…

Hardware Architecture · Computer Science 2026-05-26 Sitian Chen , Yusen Li , Yao Chen , Minwen Deng , Jintao Meng , Amelie Chi Zhou

The exascale race is at an end with the announcement of the Aurora and Frontier machines. This next generation of supercomputers utilize diverse hardware architectures to achieve their compute performance, providing an added onus on the…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-11-26 Rahulkumar Gayatri , Stan Moore , Evan Weinberg , Nicholas Lubbers , Sarah Anderson , Jack Deslippe , Danny Perez , Aidan P. Thompson

Optimization of searching the best possible action depending on various states like state of environment, system goal etc. has been a major area of study in computer systems. In any search algorithm, searching best possible solution from…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-08-10 Shubhendra Pal Singhal , M. Sridevi

Combinatorial optimization is essential across numerous disciplines. Traditional metaheuristics excel at exploring complex solution spaces efficiently, yet they often struggle with scalability. Deep learning has become a viable alternative…

Emerging Technologies · Computer Science 2025-04-09 Aitor Morais , Eneko Osaba , Iker Pastor , Izaskun Oregui

The generalized quadratic assignment problem (GQAP) is one of the hardest problems to solve in the operations research area. The GQAP addressed in this work is defined as the task of minimizing the assignment and transportation costs of…

Neural and Evolutionary Computing · Computer Science 2023-10-11 Mojtaba A. Farahani , Alan McKendall

We implement a quantum optimal control algorithm based on automatic differentiation and harness the acceleration afforded by graphics processing units (GPUs). Automatic differentiation allows us to specify advanced optimization criteria and…

Quantum Physics · Physics 2017-04-19 Nelson Leung , Mohamed Abdelhafez , Jens Koch , David I. Schuster

DL inference queries play an important role in diverse internet services and a large fraction of datacenter cycles are spent on processing DL inference queries. Specifically, the matrix-matrix multiplication (GEMM) operations of…

Hardware Architecture · Computer Science 2020-12-02 Benjamin Y. Cho , Jeageun Jung , Mattan Erez

We describe a parallel approximation algorithm for maximizing monotone submodular functions subject to hereditary constraints on distributed memory multiprocessors. Our work is motivated by the need to solve submodular optimization problems…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-18 Shivaram Gopal , S M Ferdous , Hemanta K. Maji , Alex Pothen

The two main thrusts of computational science are more accurate predictions and faster calculations; to this end, the zeitgeist in molecular dynamics (MD) simulations is pursuing machine learned and data driven interatomic models, e.g.…

Computational Physics · Physics 2020-02-24 Saaketh Desai , Samuel Temple Reeve , James F. Belak

Large matrix multiplication is a cornerstone of modern machine learning workloads, yet traditional approaches suffer from cubic computational complexity (e.g., $\mathcal{O}(n^3)$ for a matrix of size $n\times n$). We present Low-Rank GEMM,…

Performance · Computer Science 2025-11-25 Alfredo Metere

This thesis investigates the use of problem-specific knowledge to enhance a genetic algorithm approach to multiple-choice optimisation problems.It shows that such information can significantly enhance performance, but that the choice of…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin

Graph neural networks (GNNs), an emerging deep learning model class, can extract meaningful representations from highly expressive graph-structured data and are therefore gaining popularity for wider ranges of applications. However, current…

Machine Learning · Computer Science 2021-04-27 Chien-Yu Lin , Liang Luo , Luis Ceze

In this work we propose an accelerated stochastic learning system for very large-scale applications. Acceleration is achieved by mapping the training algorithm onto massively parallel processors: we demonstrate a parallel, asynchronous GPU…

Machine Learning · Computer Science 2017-02-24 Thomas Parnell , Celestine Dünner , Kubilay Atasu , Manolis Sifalakis , Haris Pozidis

Genetic Algorithms (GA) are a class of metaheuristic global optimization methods inspired by the process of natural selection among individuals in a population. Despite their widespread use, a comprehensive theoretical analysis of these…

Optimization and Control · Mathematics 2025-02-24 Giacomo Borghi , Lorenzo Pareschi

A lot of recent progress has been made in ultra low-bit quantization, promising significant improvements in latency, memory footprint and energy consumption on edge devices. Quantization methods such as Learned Step Size Quantization can…

3D Gaussian splatting (3DGS) is a transformative technique with profound implications on novel view synthesis and real-time rendering. Given its importance, there have been many attempts to improve its performance. However, with the…

Hardware Architecture · Computer Science 2025-10-14 Yi Hu , Huiyang Zhou