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This paper investigates the problem of pseudo-healthy synthesis that is defined as synthesizing a subject-specific pathology-free image from a pathological one. Recent approaches based on Generative Adversarial Network (GAN) have been…

In this research, we introduce an innovative method for synthesizing medical images using generative adversarial networks (GANs). Our proposed GANs method demonstrates the capability to produce realistic synthetic images even when trained…

The identification of lesion within medical image data is necessary for diagnosis, treatment and prognosis. Segmentation and classification approaches are mainly based on supervised learning with well-paired image-level or voxel-level…

Exploiting learning algorithms under scarce data regimes is a limitation and a reality of the medical imaging field. In an attempt to mitigate the problem, we propose a data augmentation protocol based on generative adversarial networks. We…

Pseudo healthy synthesis, i.e. the creation of a subject-specific `healthy' image from a pathological one, could be helpful in tasks such as anomaly detection, understanding changes induced by pathology and disease or even as data…

Generative adversarial networks (GANs) are a class of unsupervised machine learning algorithms that can produce realistic images from randomly-sampled vectors in a multi-dimensional space. Until recently, it was not possible to generate…

We propose a new generative adversarial architecture to mitigate imbalance data problem for the task of medical image semantic segmentation where the majority of pixels belong to a healthy region and few belong to lesion or non-health…

Understanding the intensity characteristics of brain lesions is key for defining image-based biomarkers in neurological studies and for predicting disease burden and outcome. In this work, we present a novel foreground-based generative…

Pseudo-healthy synthesis is the task of creating a subject-specific `healthy' image from a pathological one. Such images can be helpful in tasks such as anomaly detection and understanding changes induced by pathology and disease. In this…

In medical imaging, access to data is commonly limited due to patient privacy restrictions and the issue that it can be difficult to acquire enough data in the case of rare diseases.[1] The purpose of this investigation was to develop a…

Data scarcity and class imbalance are two fundamental challenges in many machine learning applications to healthcare. Breast cancer classification in mammography exemplifies these challenges, with a malignancy rate of around 0.5% in a…

We propose a new generative adversarial architecture to mitigate imbalance data problem in medical image semantic segmentation where the majority of pixels belongs to a healthy region and few belong to lesion or non-health region. A model…

Despite their recent successes, GAN models for semantic image synthesis still suffer from poor image quality when trained with only adversarial supervision. Historically, additionally employing the VGG-based perceptual loss has helped to…

Segmentation of regions of interest (ROIs) for identifying abnormalities is a leading problem in medical imaging. Using machine learning for this problem generally requires manually annotated ground-truth segmentations, demanding extensive…

Existing deep learning-based approaches for histopathology image analysis require large annotated training sets to achieve good performance; but annotating histopathology images is slow and resource-intensive. Conditional generative…

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

Artificial intelligence and machine learning techniques have the promise to revolutionize the field of digital pathology. However, these models demand considerable amounts of data, while the availability of unbiased training data is…

Anatomical landmark segmentation and pathology localization are important steps in automated analysis of medical images. They are particularly challenging when the anatomy or pathology is small, as in retinal images and cardiac MRI, or when…

In medical imaging, image synthesis is the estimation process of one image (sequence, modality) from another image (sequence, modality). Since images with different modalities provide diverse biomarkers and capture various features,…

Generative adversarial networks (GANs) offer an effective solution to the image-to-image translation problem, thereby allowing for new possibilities in medical imaging. They can translate images from one imaging modality to another at a low…