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The outbreak of COVID-19 in 2020 has led to a surge in interest in the mathematical modeling of infectious diseases. Such models are usually defined as compartmental models, in which the population under study is divided into compartments…

Populations and Evolution · Quantitative Biology 2021-02-16 Malú Grave , Alex Viguerie , Gabriel F. Barros , Alessandro Reali , Alvaro L. G. A. Coutinho

In the wake of the 2020 COVID-19 epidemic, much work has been performed on the development of mathematical models for the simulation of the epidemic, and of disease models generally. Most works follow the susceptible-infected-removed (SIR)…

Numerical Analysis · Mathematics 2022-05-18 Nicola Guglielmi , Elisa Iacomini , Alex Viguerie

Objective: COVID-19 has spread worldwide and made a huge influence across the world. Modeling the infectious spread situation of COVID-19 is essential to understand the current condition and to formulate intervention measurements.…

Machine Learning · Computer Science 2023-06-23 Ruhan Liu , Jiajia Li , Yang Wen , Huating Li , Ping Zhang , Bin Sheng , David Dagan Feng

We present a unifying, tractable approach for studying the spread of viruses causing complex diseases requiring to be modeled using a large number of types (e.g., infective stage, clinical state, risk factor class). We show that recording…

The outbreak of COVID-19 in 2020 has led to a surge in the interest in the mathematical modeling of infectious diseases. Disease transmission may be modeled as compartmental models, in which the population under study is divided into…

Populations and Evolution · Quantitative Biology 2020-10-27 Malú Grave , Alvaro L. G. A. Coutinho

Highly-interconnected societies difficult to model the spread of infectious diseases such as COVID-19. Single-region SIR models fail to account for incoming forces of infection and expanding them to a large number of interacting regions…

Machine Learning · Computer Science 2023-11-06 Adrian Rojas-Campos , Lukas Stelz , Pascal Nieters

This paper introduces a novel hybrid model combining Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) to simulate infectious disease dynamics across geographic regions. By leveraging the spatial detail of…

Dynamical Systems · Mathematics 2025-11-18 Kristina Kehrer , Martin Weiser , Tim Conrad

In this paper, we study the effectiveness of the modelling approach on the pandemic due to the spreading of the novel COVID-19 disease and develop a susceptible-infected-removed (SIR) model that provides a theoretical framework to…

Populations and Evolution · Quantitative Biology 2020-08-26 Ian Cooper , Argha Mondal , Chris G. Antonopoulos

The global pandemic due to the outbreak of COVID-19 ravages the whole world for more than two years in which all the countries are suffering a lot since December 2019. In order to control this ongoing waves of epidemiological infections,…

Populations and Evolution · Quantitative Biology 2022-02-11 Kalpita Ghosh , Asim Kumar Ghosh

In this article, we model and study the spread of COVID-19 in Germany, Japan, India and highly impacted states in India, i.e., in Delhi, Maharashtra, West Bengal, Kerala and Karnataka. We consider recorded data published in Worldometers and…

Physics and Society · Physics 2022-03-15 Ian Cooper , Argha Mondal , Chris G. Antonopoulos , Arindam Mishra

The growing literature on the propagation of COVID-19 relies on various dynamic SIR-type models (Susceptible-Infected-Recovered) which yield model-dependent results. For transparency and ease of comparing the results, we introduce a common…

Populations and Evolution · Quantitative Biology 2020-06-19 Christian Gourieroux , Joann Jasiak

The correct evaluation of the reproductive number $R$ for COVID-19 -- which characterizes the average number of secondary cases generated by each typical primary case -- is central in the quantification of the potential scope of the…

Applications · Statistics 2021-04-15 Claire Donnat , Susan Holmes

The aim of this study is to propose a modified Susceptible-Exposed-Infectious-Removed (SEIR) model that describes the behaviour of symptomatic, asymptomatic and hospitalized patients of COVID-19 epidemic, including the effect of demographic…

The susceptible-infected-recovered (SIR) model has been used extensively to model disease spread and other processes. Despite the widespread usage of this ordinary differential equation (ODE) based model which represents the mean-field…

Dynamical Systems · Mathematics 2016-12-28 Ekkehard Beck , Benjamin Armbruster

Ordinary differential equations (ODE) are a popular tool to model the spread of infectious diseases, yet they implicitly assume an exponential distribution to describe the flow from one infection state to another. However, scientific…

Numerical Analysis · Mathematics 2025-10-13 Anna Wendler , Lena Plötzke , Hannah Tritzschak , Martin J. Kühn

We study the spread of susceptible-infected-recovered (SIR) infectious diseases where an individual's infectiousness and probability of recovery depend on his/her "age" of infection. We focus first on early outbreak stages when stochastic…

Populations and Evolution · Quantitative Biology 2009-05-14 Joel Miller , Bahman Davoudi , Rafael Meza , Anja Slim , Babak Pourbohloul

It is common to use a compartmental, fluid model described by a system of ordinary differential equations (ODEs) to model disease spread. In addition to their simplicity, these models are also the mean-field approximations of more accurate…

Probability · Mathematics 2016-04-15 Benjamin Armbruster , Ekkehard Beck

Compartmental models like the Susceptible-Infected-Recovered (SIR)\cite{Kermack1927} and its extensions such as the Susceptible-Exposed-Infected-Recovered (SEIRS)\cite{Ottar2020,Ignazio2021,Grimm2021,Paoluzzi2021} are commonly used to model…

Populations and Evolution · Quantitative Biology 2025-07-14 Kasturi Banerjee , Subhankar Ray , Jayalakshmi Shamanna

We introduce an extension to Kermack and McKendrick's classic susceptible-infected-recovered (SIR) model in epidemiology, whose underlying mechanism of infection consists of individuals attending randomly generated social gatherings. This…

Probability · Mathematics 2024-05-08 Roberto Cortez

The COVID-19 pandemic has been a great catastrophe that upended human lives and caused millions of deaths all over the world. The rapid spread of the virus, with its early-stage exponential growth and subsequent 'waves', caught many medical…

Populations and Evolution · Quantitative Biology 2022-05-31 Anne V. Ginzburg , Valeriy V. Ginzburg , Julia O. Ginzburg , Ana Garcia Arias , Leela Rakesh
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