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Simulations of chemical dynamics are a powerful means for understanding chemistry. However, classical computers struggle to simulate many chemical processes, especially non-adiabatic ones, where the Born-Oppenheimer approximation breaks…

This work introduces ParAMS -- a versatile Python package that aims to make parameterization workflows in computational chemistry and physics more accessible, transparent and reproducible. We demonstrate how ParAMS facilitates the parameter…

Chemical Physics · Physics 2021-05-18 Leonid Komissarov , Robert Rüger , Matti Hellström , Toon Verstraelen

The data produced by the future space-based millihertz gravitational-wave detector LISA will require nontrivial pre-processing, which might affect the science results. It is crucial to demonstrate the feasibility of such processing…

Instrumentation and Methods for Astrophysics · Physics 2023-05-22 Jean-Baptiste Bayle , Olaf Hartwig , Marc Lilley , Aurélien Hees , Christian Chapman-Bird , Graham Woan , Peter Wolf

Differentiable programming has recently received much interest as a paradigm that facilitates taking gradients of computer programs. While the corresponding flexible gradient-based optimization approaches so far have been used predominantly…

High-fidelity electron microscopy simulations required for quantitative crystal structure refinements face a fundamental challenge: while physical interactions are well-described theoretically, real-world experimental effects are…

In the pursuit of sustainable manufacturing, ultra-short pulse laser micromachining stands out as a promising solution while also offering high-precision and qualitative laser processing. However, unlocking the full potential of ultra-short…

Signal Processing · Electrical Eng. & Systems 2025-12-03 Luis Correas-Naranjo , Miguel Camacho-Sánchez , Laëtitia Launet , Milena Zuric , Valery Naranjo

Differentiable physics provides a new approach for modeling and understanding the physical systems by pairing the new technology of differentiable programming with classical numerical methods for physical simulation. We survey the rapidly…

Machine Learning · Computer Science 2021-09-17 Bharath Ramsundar , Dilip Krishnamurthy , Venkatasubramanian Viswanathan

This tutorial introduces a systematic approach for addressing the key question of quantum metrology: For a generic task of sensing an unknown parameter, what is the ultimate precision given a constrained set of admissible strategies. The…

Quantum Physics · Physics 2024-12-19 Qiushi Liu , Zihao Hu , Haidong Yuan , Yuxiang Yang

A programmable quantum processor is a fundamental model of quantum computation. In this model, any quantum channel can be approximated by applying a fixed universal quantum operation onto an input state and a quantum `program' state, whose…

Quantum Physics · Physics 2020-05-20 Leonardo Banchi , Jason Pereira , Seth Lloyd , Stefano Pirandola

The construction of good effective models is an essential part of understanding and simulating complex systems in many areas of science. It is a particular challenge for correlated many body quantum systems displaying emergent physics. We…

Strongly Correlated Electrons · Physics 2020-07-01 Jonas B. Rigo , Andrew K. Mitchell

We typically construct optimal designs based on a single objective function. To better capture the breadth of an experiment's goals, we could instead construct a multiple objective optimal design based on multiple objective functions. While…

Methodology · Statistics 2023-03-09 Lucy L. Gao , Jane J. Ye , Shangzhi Zeng , Julie Zhou

In robotics, methods and softwares usually require optimizations of hyperparameters in order to be efficient for specific tasks, for instance industrial bin-picking from homogeneous heaps of different objects. We present a developmental…

Robotics · Computer Science 2020-07-31 Maxime Petit , Emmanuel Dellandrea , Liming Chen

We consider the effects of parameter uncertainty on the optimal radiation schedule in the context of the linear-quadratic model. Our interest arises from the observation that if inter-patient variations in OAR and tumor sensitivities to…

Tissues and Organs · Quantitative Biology 2015-06-05 Hamidreza Badri , Yoichi Watanabe , Kevin Leder

The overarching goal of beamline design is to achieve a high brightness electron beam from the beamline. Traditional beamline design studies involved separate optimizations of radio-frequency cavities, magnets, and beam dynamics using…

Accelerator Physics · Physics 2023-11-17 Gongxiaohui Chen , Tyler H. Chang , John Power , Chungunag Jing

One of the challenges in computational acoustics is the identification of models that can simulate and predict the physical behavior of a system generating an acoustic signal. Whenever such models are used for commercial applications an…

Quality control in industrial processes is increasingly making use of prior scientific knowledge, often encoded in physical models that require numerical approximation. Statistical prediction, and subsequent optimization, is key to ensuring…

Other Statistics · Statistics 2018-10-23 Antony Overstall , David Woods , Kieran Martin

Machine learning pipelines often rely on optimization procedures to make discrete decisions (e.g., sorting, picking closest neighbors, or shortest paths). Although these discrete decisions are easily computed, they break the…

Machine Learning · Computer Science 2020-06-11 Quentin Berthet , Mathieu Blondel , Olivier Teboul , Marco Cuturi , Jean-Philippe Vert , Francis Bach

In context of highly complex energy system experiments, sensitivity analysis is gaining more and more importance to investigate the effects changing parameterization has on the outcome. Thus, it is crucial how to design an experiment to…

Computational Engineering, Finance, and Science · Computer Science 2024-10-23 Jan Sören Schwarz , Leonard Enrique Ramos Perez , Minh Cong Pham , Kai Heussen , Quoc Tuan Tran

We develop adaptive discretization algorithms for locally optimal experimental design of nonlinear prediction models. With these algorithms, we refine and improve a pertinent state-of-the-art algorithm in various respects. We establish…

Optimization and Control · Mathematics 2024-06-04 Jochen Schmid , Philipp Seufert , Michael Bortz

Bayesian optimization (BO) is one of the most effective methods for closed-loop experimental design and black-box optimization. However, a key limitation of BO is that it is an inherently sequential algorithm (one experiment is proposed per…

Machine Learning · Statistics 2023-11-21 Leonardo D. González , Victor M. Zavala