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In this work we adopt a statistical mechanics approach to investigate basic, systemic features exhibited by adaptive immune systems. The lymphocyte network made by B-cells and T-cells is modeled by a bipartite spin-glass, where, following…

Cell Behavior · Quantitative Biology 2015-06-04 Elena Agliari , Adriano Barra , Silvia Bartolucci , Andrea Galluzzi , Francesco Guerra , Francesco Moauro

Understanding the role of network structure in the evolution of cooperation is a key research goal at the intersection between physics and biology. Recent studies have particularly focused on multiplex networks given that multiple social…

Physics and Society · Physics 2020-07-27 Hirofumi Takesue

Nowadays, multiscale modelling is recognized as the most suitable way to study biological processes. Indeed, almost every phenomenon in nature exhibits a multiscale behaviour, i.e., it is the outcome of interactions that occur at different…

Formal Languages and Automata Theory · Computer Science 2011-08-18 Federico Buti , Massimo Callisto De Donato , Flavio Corradini , Emanuela Merelli , Luca Tesei

Many social and biological networks periodically change over time with daily, weekly, and other cycles. Thus motivated, we formulate and analyze susceptible-infectious-susceptible (SIS) epidemic models over temporal networks with periodic…

Physics and Society · Physics 2024-11-22 Maisha Islam Sejunti , Dane Taylor , Naoki Masuda

Complex networks provide us a new view for investigation of immune systems. In this paper we collect data through STRING database and present a model with cooperation network theory. The cytokine-protein network model we consider is…

Adaptation and Self-Organizing Systems · Physics 2007-12-06 Sheng-Rong Zou , Ta Zhou , Yu-Jing Peng , Zhong-Wei Guo , Chang-gui Gu , Da-Ren He

Capturing both the structural and temporal aspects of interactions is crucial for many real world datasets like contact between individuals. Using the link stream formalism to capture the dynamic of the systems, we tackle the issue of…

Social and Information Networks · Computer Science 2018-04-13 Thibaud Arnoux , Lionel Tabourier , Matthieu Latapy

We propose a lattice dynamical system that arises in a discrete diffusive two-group epidemic model with latency in a patchy environment. The model considers the SIS form and latency of the disease in group 1, while the SIR form without…

Populations and Evolution · Quantitative Biology 2024-10-21 Chufen Wu , Yonghui Xia , Jianshe Yu

We discuss the effects of a trapping space-dependent potential on the critical dynamics of lattice gas models. Scaling arguments provide a dynamic trap-size scaling framework to describe how critical dynamics develops in the large trap-size…

Statistical Mechanics · Physics 2015-05-28 Gianluca Costagliola , Ettore Vicari

Network topology and nodal dynamics are two fundamental stones of adaptive networks. Detailed and accurate knowledge of these two ingredients is crucial for understanding the evolution and mechanism of adaptive networks. In this paper, by…

Physics and Society · Physics 2013-09-24 Jie Zhou , Gaoxi Xiao , Guanrong Chen

We study a stochastic process describing the onset of spreading dynamics of an epidemic in a population composed by individuals of three classes: susceptible (S), infected (I), and recovered (R). The stochastic process is defined by local…

Statistical Mechanics · Physics 2015-05-13 David R. de Souza , Tânia Tomé

We study the emergent dynamics of a network of synaptically coupled slow-fast oscillators. Synaptic coupling provides a network-level positive feedback mechanism that cooperates with cellular-level positive feedback to ignite in-phase…

Chaotic Dynamics · Physics 2021-10-06 Omar Juarez-Alvarez , Alessio Franci

Sepsis and septic shock are a critical medical condition affecting millions globally, with a substantial mortality rate. This paper uses state-of-the-art deep learning (DL) architectures to introduce a multi-step forecasting system to…

Machine Learning · Computer Science 2023-11-09 Anubhav Bhatti , Yuwei Liu , Chen Dan , Bingjie Shen , San Lee , Yonghwan Kim , Jang Yong Kim

We present a novel methodology for integrating high resolution longitudinal data with the dynamic prediction capabilities of survival models. The aim is two-fold: to improve the predictive power while maintaining interpretability of the…

Applications · Statistics 2024-03-07 Giacomo Lancia , Meri Varkila , Olaf Cremer , Cristian Spitoni

Dynamics on networks is considered from the perspective of Markov stochastic processes. We partially describe the state of the system through network motifs and infer any missing data using the available information. This versatile approach…

The lateral diffusion and trapping of protein receptors within the postsynaptic membrane of a neuron plays a key role in determining the strength of synaptic connections and their regulation during learning and memory. In this paper we…

Statistical Mechanics · Physics 2023-07-19 Paul C Bressloff

Networks of contacts capable of spreading infectious diseases are often observed to be highly heterogeneous, with the majority of individuals having fewer contacts than the mean, and a significant minority having relatively very many…

Physics and Society · Physics 2016-12-21 César Parra-Rojas , Thomas House , Alan J. McKane

We introduce a mathematical model of symbiosis between different species by taking into account the influence of each species on the carrying capacities of the others. The modeled entities can pertain to biological and ecological societies…

Biological Physics · Physics 2012-06-06 V. I. Yukalov , E. P. Yukalova , D. Sornette

Disease awareness in infection dynamics can be modeled with adaptive contact networks whose rewiring rules reflect the attempt by susceptibles to avoid infectious contacts. Simulations of this type of models show an active phase with…

Adaptation and Self-Organizing Systems · Physics 2012-12-06 Stefan Wieland , Tomas Aquino , Ana Nunes

When analyzing animal movement, it is important to account for interactions between individuals. However, statistical models for incorporating interaction behavior in movement models are limited. We propose an approach that models dependent…

Applications · Statistics 2015-08-04 James C. Russell , Ephraim M. Hanks , Murali Haran

Conditions such as insomnia, cardiac arrhythmia and jet-lag share a common feature: they are all related to the ability of biological systems to synchronize with the day-night cycle. When organisms lose resilience, this ability of…

Quantitative Methods · Quantitative Biology 2020-03-27 Pablo Rodríguez-Sánchez , Egbert H. van Nes , Marten Scheffer