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Single-cell RNA sequencing (scRNA-seq) enables researchers to analyze gene expression at single-cell level. One important task in scRNA-seq data analysis is unsupervised clustering, which helps identify distinct cell types, laying down the…

Genomics · Quantitative Biology 2023-12-29 Weikang Jiang , Jinxian Wang , Jihong Guan , Shuigeng Zhou

In this thesis, we propose several modelling strategies to tackle evolving data in different contexts. In the framework of static clustering, we start by introducing a soft kernel spectral clustering (SKSC) algorithm, which can better deal…

Social and Information Networks · Computer Science 2014-11-24 Rocco Langone

Data collection from manual labeling provides domain-specific and task-aligned supervision for data-driven approaches, and a critical mass of well-annotated resources is required to achieve reasonable performance in natural language…

Computation and Language · Computer Science 2023-11-09 Zhengyuan Liu , Hai Leong Chieu , Nancy F. Chen

We present a machine learning framework and a new test bed for data mining from the Slurm Workload Manager for high-performance computing (HPC) clusters. The focus was to find a method for selecting features to support decisions: helping…

Machine Learning · Computer Science 2020-12-16 Adedolapo Okanlawon , Huichen Yang , Avishek Bose , William Hsu , Dan Andresen , Mohammed Tanash

A biological experiment is the most reliable way of assigning function to a protein. However, in the era of high-throughput sequencing, scientists are unable to carry out experiments to determine the function of every single gene product.…

Quantitative Methods · Quantitative Biology 2016-01-07 Iddo Friedberg , Predrag Radivojac

Image annotation aims to annotate a given image with a variable number of class labels corresponding to diverse visual concepts. In this paper, we address two main issues in large-scale image annotation: 1) how to learn a rich feature…

Computer Vision and Pattern Recognition · Computer Science 2018-10-22 Yulei Niu , Zhiwu Lu , Ji-Rong Wen , Tao Xiang , Shih-Fu Chang

Multi-instance learning is common for computer vision tasks, especially in biomedical image processing. Traditional methods for multi-instance learning focus on designing feature aggregation methods and multi-instance classifiers, where the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-18 Yanlun Tu , Houchao Lei , Wei Long , Yang Yang

In this work, we developed an efficient approach to compute ensemble averages in systems with pairwise-additive energetic interactions between the entities. Methods involving full enumeration of the configuration space result in exponential…

Biomolecules · Quantitative Biology 2020-10-13 Arun V. Sathanur , Nathan A. Baker

Clustering analysis plays an important role in scientific research and commercial application. K-means algorithm is a widely used partition method in clustering. However, it is known that the K-means algorithm may get stuck at suboptimal…

Neural and Evolutionary Computing · Computer Science 2014-05-26 M. H. Marghny , Rasha M. Abd El-Aziz , Ahmed I. Taloba

This paper studies a factor modeling-based approach for clustering high-dimensional data generated from a mixture of strongly correlated variables. Statistical modeling with correlated structures pervades modern applications in economics,…

Statistics Theory · Mathematics 2024-08-23 Shange Tang , Soham Jana , Jianqing Fan

The community detection problem on multilayer networks have drawn much interest. When the nodal covariates ar also present, few work has been done to integrate information from both sources. To leverage the multilayer networks and the…

Methodology · Statistics 2025-03-13 Da Zhao , Wanjie Wang , Jialiang Li

Fine-grained IP geolocation plays a critical role in applications such as location-based services and cybersecurity. Most existing fine-grained IP geolocation methods are regression-based; however, due to noise in the input data, these…

Machine Learning · Computer Science 2025-01-29 Tianzi Zhao , Xinran Liu , Zhaoxin Zhang , Dong Zhao , Ning Li , Zhichao Zhang , Xinye Wang

A widely used approach for extracting information from gene expression data employ the construction of a gene co-expression network and the subsequent application of algorithms that discover network structure. In particular, a common goal…

Genomics · Quantitative Biology 2024-08-20 Niloofar Aghaieabiane , Ioannis Koutis

Kernel spectral clustering corresponds to a weighted kernel principal component analysis problem in a constrained optimization framework. The primal formulation leads to an eigen-decomposition of a centered Laplacian matrix at the dual…

Social and Information Networks · Computer Science 2014-12-03 Raghvendra Mall , Rocco Langone , Johan A. K. Suykens

As far as Scene Graph Generation (SGG), coarse and fine predicates mix in the dataset due to the crowd-sourced labeling, and the long-tail problem is also pronounced. Given this tricky situation, many existing SGG methods treat the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Youming Deng , Yansheng Li , Yongjun Zhang , Xiang Xiang , Jian Wang , Jingdong Chen , Jiayi Ma

Annotation quality and quantity positively affect the learning performance of sequence labeling, a vital task in Natural Language Processing. Hiring domain experts to annotate a corpus is very costly in terms of money and time.…

Human-Computer Interaction · Computer Science 2023-07-04 Nasim Sabetpour , Adithya Kulkarni , Sihong Xie , Qi Li

Traditional clustering methods are limited when dealing with huge and heterogeneous groups of gene expression data, which motivates the development of bi-clustering methods. Bi-clustering methods are used to mine bi-clusters whose subsets…

Computer Vision and Pattern Recognition · Computer Science 2020-05-13 Kaijie Xu , Witold Pedrycz , Zhiwu Li , Yinghui Quan , Weike Nie

Spectral clustering is one of the most effective clustering approaches that capture hidden cluster structures in the data. However, it does not scale well to large-scale problems due to its quadratic complexity in constructing similarity…

Machine Learning · Computer Science 2019-11-26 Lingfei Wu , Pin-Yu Chen , Ian En-Hsu Yen , Fangli Xu , Yinglong Xia , Charu Aggarwal

We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic descriptors, sequence based attributes, and predicted…

Genomics · Quantitative Biology 2007-05-23 Babak Shahbaba , Radford M. Neal

Graph-structured data commonly have node annotations. A popular approach for inference and learning involving annotated graphs is to incorporate annotations into a statistical model or algorithm. By contrast, we consider a more direct…

Social and Information Networks · Computer Science 2020-10-07 Tatsuro Kawamoto
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