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It's well-known that inverse problems are ill-posed and to solve them meaningfully one has to employ regularization methods. Traditionally, popular regularization methods have been the penalized Variational approaches. In recent years, the…

Machine Learning · Computer Science 2022-02-17 Abinash Nayak

Computed tomography (CT) plays an important role in lung malignancy diagnostics and therapy assessment and facilitating precision medicine delivery. However, the use of personalized imaging protocols poses a challenge in large-scale…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Md Selim , Jie Zhang , Baowei Fei , Guo-Qiang Zhang , Jin Chen

Recent developments in deep learning have revolutionized the paradigm of image restoration. However, its applications on real image denoising are still limited, due to its sensitivity to training data and the complex nature of real image…

Computer Vision and Pattern Recognition · Computer Science 2019-05-06 Jin Zeng , Jiahao Pang , Wenxiu Sun , Gene Cheung

Computed Tomography (CT) takes X-ray measurements on the subjects to reconstruct tomographic images. As X-ray is radioactive, it is desirable to control the total amount of dose of X-ray for safety concerns. Therefore, we can only select a…

Medical Physics · Physics 2021-09-15 Ziju Shen , Yufei Wang , Dufan Wu , Xu Yang , Bin Dong

We present deformable unsupervised medical image registration using a randomly-initialized deep convolutional neural network (CNN) as regularization prior. Conventional registration methods predict a transformation by minimizing…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…

Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Herman Verinaz-Jadan , Su Yan

Tomographic image reconstruction with deep learning is an emerging field, but a recent landmark study reveals that several deep reconstruction networks are unstable for computed tomography (CT) and magnetic resonance imaging (MRI).…

Image and Video Processing · Electrical Eng. & Systems 2021-09-14 Weiwen Wu , Dianlin Hu , Wenxiang Cong , Hongming Shan , Shaoyu Wang , Chuang Niu , Pingkun Yan , Hengyong Yu , Varut Vardhanabhuti , Ge Wang

While remarkable advances have been made in Computed Tomography (CT), capturing CT images with non-standardized protocols causes low reproducibility regarding radiomic features, forming a barrier on CT image analysis in a large scale.…

Image and Video Processing · Electrical Eng. & Systems 2021-07-06 Md Selim , Jie Zhang , Baowei Fei , Guo-Qiang Zhang , Jin Chen

The importance of regularization has been well established in image reconstruction -- which is the computational inversion of imaging forward model -- with applications including deconvolution for microscopy, tomographic reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Sanjay Viswanath , Manu Ghulyani , Muthuvel Arigovindan

In the practical applications of computed tomography imaging, the projection data may be acquired within a limited-angle range and corrupted by noises due to the limitation of scanning conditions. The noisy incomplete projection data…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Qifeng Gao , Rui Ding , Linyuan Wang , Bin Xue , Yuping Duan

The development of compressed sensing methods for magnetic resonance (MR) image reconstruction led to an explosion of research on models and optimization algorithms for MR imaging (MRI). Roughly 10 years after such methods first appeared in…

Image and Video Processing · Electrical Eng. & Systems 2019-06-14 Jeffrey A Fessler

Electron ptychography enables dose-efficient atomic-resolution imaging, but conventional reconstruction algorithms suffer from noise sensitivity, slow convergence, and extensive manual hyperparameter tuning for regularization, especially in…

Image and Video Processing · Electrical Eng. & Systems 2025-11-12 Arthur R. C. McCray , Stephanie M. Ribet , Georgios Varnavides , Colin Ophus

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent application of deep learning methods for image reconstruction provides a successful data-driven approach to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-22 Ling Chen , Zhishen Huang , Yong Long , Saiprasad Ravishankar

Recently, generative diffusion priors have made huge strides as inverse problem solvers, including the ability to be adapted for inference on out-of-distribution data. Concurrently, implicit neural representations (INRs) have emerged as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Maliha Hossain , Haley Duba-Sullivan , Amirkoushyar Ziabari

The generalized minimal residual (GMRES) algorithm is applied to image reconstruction using linear computed tomography (CT) models. The GMRES algorithm iteratively solves square, non-symmetric linear systems and it has practical application…

Medical Physics · Physics 2022-05-04 Emil Y. Sidky , Per Christian Hansen , Jakob S. Jørgensen , Xiaochuan Pan

Learning neural networks using only few available information is an important ongoing research topic with tremendous potential for applications. In this paper, we introduce a powerful regularizer for the variational modeling of inverse…

Machine Learning · Computer Science 2023-05-17 Fabian Altekrüger , Alexander Denker , Paul Hagemann , Johannes Hertrich , Peter Maass , Gabriele Steidl

One of the advantages of spectral computed tomography (CT) is it can achieve accurate material components using the material decomposition methods. The image-based material decomposition is a common method to obtain specific material…

Image and Video Processing · Electrical Eng. & Systems 2019-10-18 Weiwen Wu , Peijun Chen , Vince Vardhanabhuti , Weifei Wu , Hengyong Yu

X-ray imaging dose from serial cone-beam CT (CBCT) scans raises a clinical concern in most image guided radiation therapy procedures. It is the goal of this paper to develop a fast GPU-based algorithm to reconstruct high quality CBCT images…

Medical Physics · Physics 2015-05-19 Xun Jia , Bin Dong , Yifei Lou , Steve B. Jiang

Assume you encounter an inverse problem that shall be solved for a large number of data, but no ground-truth data is available. To emulate this encounter, in this study, we assume it is unknown how to solve the imaging problem of Computed…

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