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The use of oncolytic viruses as cancer treatment has received considerable attention in recent years, however the spatial dynamics of this viral infection is still poorly understood. We present here a stochastic agent-based model describing…

Populations and Evolution · Quantitative Biology 2023-09-06 David Morselli , Marcello Edoardo Delitala , Federico Frascoli

In this paper, we study into the impact of the preference of an individual for public transport on the spread of infectious disease, through a quantity known as the public mobility. Our theoretical and numerical results based on a…

Physics and Society · Physics 2012-08-29 Jie Zhou , Ning Ning Chung , Lock Yue Chew , Choy Heng Lai

Understanding dynamics of an outbreak like that of COVID-19 is important in designing effective control measures. This study aims to develop an agent based model that compares changes in infection progression by manipulating different…

Populations and Evolution · Quantitative Biology 2021-06-24 Anik Burman , Sayak Chatterjee , Pramit Ghosh , Indranil Mukhokadhyay

This study presents an integrated approach to understanding epidemic dynamics through a stochastic spatio-temporal simulation model on a multiplex network, blending physical and informational layers. The physical layer maps the geographic…

Physics and Society · Physics 2025-09-26 H. M. Shadman Tabib , Jaber Ahmed Deedar , K. M. Ariful Kabir

Human mobility and activity patterns mediate contagion on many levels, including the spatial spread of infectious diseases, diffusion of rumors, and emergence of consensus. These patterns however are often dominated by specific locations…

Physics and Society · Physics 2011-07-05 Duygu Balcan , Alessandro Vespignani

Mathematical models of motility are often based on random-walk descriptions of discrete individuals that can move according to certain rules. It is usually the case that large masses concentrated in small regions of space have a great…

Physics and Society · Physics 2022-11-23 Carles Falcó

Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load…

Physics and Society · Physics 2022-05-10 Rossella Della Marca , Nadia Loy , Andrea Tosin

We analyze the dynamics of a population of independent random walkers on a graph and develop a simple model of epidemic spreading. We assume that each walker visits independently the nodes of a finite ergodic graph in a discrete-time…

Physics and Society · Physics 2021-01-19 Michael Bestehorn , Alejandro P. Riascos , Thomas M. Michelitsch , Bernard A. Collet

The relationship between division of labor and individuals' spatial behavior in social insect colonies provides a useful context to study how social interactions influence the spreading of agent (which could be information or virus) across…

Populations and Evolution · Quantitative Biology 2020-03-31 Xisohui Guo , Jun Chen , Asma Azizi , Jennifer Fewell , Yun Kang

In this survey we report some recent results in the mathematical modeling of epidemic phenomena through the use of kinetic equations. We initially consider models of interaction between agents in which social characteristics play a key role…

Populations and Evolution · Quantitative Biology 2023-09-11 Giacomo Albi , Giulia Bertaglia , Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi , Giuseppe Toscani , Mattia Zanella

Viruses constantly undergo mutations with genomic changes. The propagation of variants of viruses is an interesting problem. We perform numerical simulations of the microscopic epidemic model based on network theory for the spread of…

Populations and Evolution · Quantitative Biology 2025-01-14 Yutaka Okabe , Akira Shudo

Drug resistance and strong contacts actually play crucial roles in epidemic spread in complex systems. Nevertheless, neither theoretical model or methodology is proposed to address this. We thus consider an edge-based epidemic spread model…

Physics and Society · Physics 2017-09-13 Peng-Bi Cui , Lei Gao , Wei Wang

We study the diffusion of epidemics on networks that are partitioned into local communities. The gross structure of hierarchical networks of this kind can be described by a quotient graph. The rationale of this approach is that individuals…

Social and Information Networks · Computer Science 2016-01-19 Stefano Bonaccorsi , Stefania Ottaviano , Delio Mugnolo , Francesco De Pellegrini

The spread of disease through a physical-contact network and the spread of information about the disease on a communication network are two intimately related dynamical processes. We investigate the asymmetrical interplay between the two…

Physics and Society · Physics 2014-05-09 Wei Wang , Ming Tang , Hui Yang , Younghae Do , Ying-Cheng Lai , GyuWon Lee

In the present paper, our goal is to establish a framework for the mathematical modelling and the analysis of the spread of an epidemic in a large population commuting regularly, typically along a time-periodic pattern, as is roughly…

Populations and Evolution · Quantitative Biology 2024-08-29 Pierre-Alexandre Bliman , Boureima Sangaré , Assane Savadogo

In recent years the research community has accumulated overwhelming evidence for the emergence of complex and heterogeneous connectivity patterns in a wide range of biological and sociotechnical systems. The complex properties of real-world…

Physics and Society · Physics 2015-09-21 Romualdo Pastor-Satorras , Claudio Castellano , Piet Van Mieghem , Alessandro Vespignani

Self-activation coupled to a transport mechanism results in traveling waves that describe polymerization reactions, forest fires, tumor growth, and even the spread of epidemics. Diffusion is a simple and commonly used model of particle…

Statistical Mechanics · Physics 2020-07-06 Keisuke Ishihara , Ashish B. George , Ryan Cornelius , Kirill S. Korolev

Rapidly mutating pathogens may be able to persist in the population and reach an endemic equilibrium by escaping hosts' acquired immunity. For such diseases, multiple biological, environmental and population-level mechanisms determine the…

Physics and Society · Physics 2019-02-07 Alberto Aleta , Andreia N. S. Hisi , Sandro Meloni , Chiara Poletto , Vittoria Colizza , Yamir Moreno

The spread of viruses in biological networks, computer networks, and human contact networks can have devastating effects; developing and analyzing mathematical models of these systems can be insightful and lead to societal benefits. Prior…

Optimization and Control · Mathematics 2016-09-19 Philip E. Paré , Angelia Nedić , Carolyn L. Beck

We study the non-equilibrium phase transition in a model for epidemic spreading on scale-free networks. The model consists of two particle species $A$ and $B$, and the coupling between them is taken to be asymmetric; $A$ induces $B$ while…

Statistical Mechanics · Physics 2009-11-11 Yong-Yeol Ahn , Naoki Masuda , Hawoong Jeong , Jae Dong Noh