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Optical enantioseparation of nanoscale matter is fundamentally limited by the intrinsic weakness of chiroptical forces compared to the dominant achiral gradient forces and thermal fluctuations. Conventional plasmonic approaches typically…

Optics · Physics 2026-02-11 Guillermo Serrera , Pablo Albella

Detecting and controlling the chirality of materials play an essential role in exploring nature, providing new avenues for material creation, discrimination, and manipulation. In such tasks, chiral reagents are essential in defining or…

Strong light-matter coupling in chiral cavities has been proposed as an effective way to selectively interact with an enantiomer that shares the same handedness as the cavity's chiral mode. We show that surface plasmons supported by a…

We present a comprehensive study of enantioselective orientation of chiral molecules excited by a pair of delayed cross-polarized femtosecond laser pulses. We show that by optimizing the pulses' parameters, a significant (~ 10%) degree of…

Optics · Physics 2022-07-20 Long Xu , Ilia Tutunnikov , Yehiam Prior , Ilya Sh. Averbukh

Sculpting sub-cycle temporal structures of optical waveforms allows one to image and even control electronic clouds in atoms, molecules and solids. Here we show how the transverse spin component arising upon spatial confinement of such…

Optics · Physics 2020-11-17 David Ayuso , Andres Ordonez , Misha Ivanov , Olga Smirnova

Chiroptical enantioselective sensing is gaining traction across various applications. However, intrinsic molecular chiroptical responses are weak, and existing amplification approaches add synthesis, manufacturing, or operational complexity…

We present a comprehensive overview of chirality and its optical manifestation in plasmonic nanosystems and nanostructures. We discuss top-down fabricated structures that range from solid metallic nanostructures to groupings of metallic…

Chiral discrimination, a problem of vital importance, has recently become an emerging frontier in ultrafast physics, with remarkable progress achieved in multiphoton and strong-field regimes. Rydberg excitations, unavoidable in the…

Distinguishing between enantiomers is crucial in the study of chiral molecules in chemistry and pharmacology. Many optical approaches rely on enantiospecific cyclic electric-dipole transitions induced by three microwave or laser beams.…

Quantum Physics · Physics 2025-12-11 Fen Zou , Yong Li , Peng Zhang

Optical nanofibers are waveguides known for their unique property to produce intense evanescent fields which have subwavelength transverse confinement easily extendable over thousands of wavelengths along the fiber axis. Moreover,…

The topological response of matter to electromagnetic fields is a property in high demand in materials design and metrology due to its robustness against noise and decoherence, stimulating recent advances in ultrafast photonics. Embedding…

A new scheme for enantiomer differentiation of chiral molecules using a pair of linearly polarized intense ultrashort laser pulses with skewed mutual polarization is presented. The technique relies on the fact that the off-diagonal…

Chemical Physics · Physics 2017-05-04 Andrey Yachmenev , Sergei N. Yurchenko

Chiral discrimination of enantiomeric biomolecules is vital in chemistry, biology, and medicine. Conventional methods, relying on circularly polarized light, face weak chiroptical signals and potential photodamage. Despite extensive efforts…

Quantum Physics · Physics 2026-01-21 Yiquan Yang , Xiaolong Hu , Wei Du , Shuhe Wu , Peiyu Yang , Guzhi Bao , Weiping Zhang

We explore a pure optical method for enantioselective orientation of chiral molecules by means of laser fields with twisted polarization. Several field implementations are considered, including a pair of delayed cross-polarized laser…

Chemical Physics · Physics 2018-03-23 I. Tutunnikov , E. Gershnabel , S. Gold , I. Sh. Averbukh

We calculate optical forces and torques exerted on a chiral dipole by chiral light fields and reveal genuinely chiral forces in combining the chiral contents of both light field and dipolar matter. Here, the optical chirality is…

Transverse spin angular momentum (SAM) of light and associated transverse chiral optical forces have received tremendous attention recently as the latter may lead to an optical separation of chiral biomolecules. In this context, the…

Optics · Physics 2016-11-03 M. H. Alizadeh , B. M. Reinhard

Structural chirality can induce counter-intuitive optical forces due to inherent symmetry properties. While optical forces on a single chiral particle in the Rayleigh regime have been well studied, optical forces in coupled chiral particles…

Optics · Physics 2020-11-04 Kah Jen Wo , Jie Peng , Madhava Krishna Prasad , Yuzhi Shi , Jensen Li , Shubo Wang

Molecular chirality detection and enantiomer discrimination are very important issues for many areas of science and technology, prompting intensive investigations via optical methods. However, these methods are hindered by the intrinsically…

We discuss how tensorial observables, available in photoelectron angular distributions resulting from interaction between isotropic chiral samples and cross polarized $\omega$-$2\omega$ bichromatic fields, allow for chiral discrimination…

Atomic Physics · Physics 2022-06-28 Andres F. Ordonez , Olga Smirnova

The manipulation and sorting of chiral nanoparticles are of fundamental importance in multidisciplinary fields ranging from biochemistry to nanophotonics. In this study, we propose a novel and controllable chirality sorting mechanism for…

Optics · Physics 2026-04-10 Hao Zhang , Xi Xie , Yijie Shen