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Automatic techniques in the context of motor speech disorders (MSDs) are typically two-class techniques aiming to discriminate between dysarthria and neurotypical speech or between dysarthria and apraxia of speech (AoS). Further, although…
Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…
Alzheimer's Disease (AD) ravages the cognitive ability of more than 5 million Americans and creates an enormous strain on the health care system. This paper proposes a machine learning predictive model for AD development without medical…
Although Alzheimer's disease detection via MRIs has advanced significantly thanks to contemporary deep learning models, challenges such as class imbalance, protocol variations, and limited dataset diversity often hinder their generalization…
Active learning methods increase classification quality by means of user feedback. An important subcategory is active learning for outlier detection with one-class classifiers. While various methods in this category exist, selecting one for…
In this work we explore how language models can be employed to analyze language and discriminate between mentally impaired and healthy subjects through the perplexity metric. Perplexity was originally conceived as an information-theoretic…
Sensory input from multiple sources is crucial for robust and coherent human perception. Different sources contribute complementary explanatory factors. Similarly, research studies often collect multimodal imaging data, each of which can…
Alzheimer's disease (AD) is an irreversible devastative neurodegenerative disorder associated with progressive impairment of memory and cognitive functions. Its early diagnosis is crucial for the development of possible future treatment…
Speech is a rich biomarker that encodes substantial information about the health of a speaker, and thus it has been proposed for the detection of numerous diseases, achieving promising results. However, questions remain about what the…
Neurodegeneration as measured through magnetic resonance imaging (MRI) is recognized as a potential biomarker for diagnosing Alzheimer's disease (AD), but is generally considered less specific than amyloid or tau based biomarkers. Due to a…
Structural magnetic resonance imaging (MRI) studies have shown that Alzheimer's Disease (AD) induces both localised and widespread neural degenerative changes throughout the brain. However, the absence of segmentation that highlights brain…
Automatic detection of Alzheimer's dementia by speech processing is enhanced when features of both the acoustic waveform and the content are extracted. Audio and text transcription have been widely used in health-related tasks, as spectral…
Objectives: The objectives of this narrative review are to summarize the current state of AI applications in neuroimaging for early Alzheimer's disease (AD) prediction and to highlight the potential of AI techniques in improving early AD…
The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…
We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This…
Alzheimer's disease and Frontotemporal dementia are two major types of dementia. Their accurate diagnosis and differentiation is crucial for determining specific intervention and treatment. However, differential diagnosis of these two types…
Background: Dementia, marked by cognitive decline, is a global health challenge. Alzheimer's disease (AD), the leading type, accounts for ~70% of cases. Electroencephalography (EEG) measures show promise in identifying AD risk, but…
Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…
Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…
The automatic early diagnosis of prodromal stages of Alzheimer's disease is of great relevance for patient treatment to improve quality of life. We address this problem as a multi-modal classification task. Multi-modal data provides richer…