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Objective: To enable privacy-preserving learning of high quality generative and discriminative machine learning models from distributed electronic health records. Methods and Results: We describe general and scalable strategy to build…

Cryptography and Security · Computer Science 2018-06-19 Marina Blanton , Ah Reum Kang , Subhadeep Karan , Jaroslaw Zola

We study a protocol for distributed computation called shuffled check-in, which achieves strong privacy guarantees without requiring any further trust assumptions beyond a trusted shuffler. Unlike most existing work, shuffled check-in…

Machine Learning · Computer Science 2023-07-06 Seng Pei Liew , Satoshi Hasegawa , Tsubasa Takahashi

Assessment of risk prediction models has primarily utilized measures of discrimination, the ROC curve AUC and C-statistic. These derive from the risk distributions of patients and nonpatients, which in turn are derived from a population…

Quantitative Methods · Quantitative Biology 2023-12-05 Ralph H. Stern

Distributed data analysis without revealing the individual data has recently attracted significant attention in several applications. A collaborative data analysis through sharing dimensionality reduced representations of data has been…

Machine Learning · Computer Science 2021-01-28 Akira Imakura , Anna Bogdanova , Takaya Yamazoe , Kazumasa Omote , Tetsuya Sakurai

We consider a problem where mutually untrusting curators possess portions of a vertically partitioned database containing information about a set of individuals. The goal is to enable an authorized party to obtain aggregate (statistical)…

Cryptography and Security · Computer Science 2013-04-18 Bing-Rong Lin , Ye Wang , Shantanu Rane

Distributed model predictive control (DMPC) has attracted extensive attention as it can explicitly handle system constraints and achieve optimal control in a decentralized manner. However, the deployment of DMPC strategies generally…

Systems and Control · Electrical Eng. & Systems 2025-11-21 Kaixiang Zhang , Yongqiang Wang , Ziyou Song , Zhaojian Li

Prior to clinical applications, it is critical that risk prediction models are evaluated in independent studies that did not contribute to model development. While prospective cohort studies provide a natural setting for model validation,…

Methodology · Statistics 2017-10-13 Parichoy Pal Choudhury , Anil K. Chaturvedi , Nilanjan Chatterjee

Federated learning has gained great attention recently as a privacy-enhancing tool to jointly train a machine learning model by multiple parties. As a sub-category, vertical federated learning (vFL) focuses on the scenario where features…

Machine Learning · Computer Science 2022-05-26 Jiankai Sun , Xin Yang , Yuanshun Yao , Junyuan Xie , Di Wu , Chong Wang

The discovery of clinical biomarkers requires large patient cohorts and is aided by a pooled data approach across institutions. In many countries, data protection constraints, especially in the clinical environment, forbid the exchange of…

Machine Learning · Statistics 2023-10-03 Daniela Zöller , Harald Binder

Privacy protection has become an increasingly pressing requirement in distributed optimization. However, equipping distributed optimization with differential privacy, the state-of-the-art privacy protection mechanism, will unavoidably…

Optimization and Control · Mathematics 2023-04-28 Yu Xuan , Yongqiang Wang

Combining data from varied sources has considerable potential for knowledge discovery: collaborating data parties can mine data in an expanded feature space, allowing them to explore a larger range of scientific questions. However, data…

Machine Learning · Computer Science 2019-11-11 Erik-Jan van Kesteren , Chang Sun , Daniel L. Oberski , Michel Dumontier , Lianne Ippel

This paper presents a novel approach to classical linear regression, enabling model computation from data streams or in a distributed setting while preserving data privacy in federated environments. We extend this framework to generalized…

Computation · Statistics 2026-05-29 Daniel Tinoco , Raquel Menezes , Carlos Baquero

Deep Learning has established in the latest years as a successful approach to address a great variety of tasks. Healthcare is one of the most promising field of application for Deep Learning approaches since it would allow to help…

Machine Learning · Computer Science 2021-10-05 Edoardo Giacomello , Michele Cataldo , Daniele Loiacono , Pier Luca Lanzi

Decentralized optimization is gaining increased traction due to its widespread applications in large-scale machine learning and multi-agent systems. The same mechanism that enables its success, i.e., information sharing among participating…

Optimization and Control · Mathematics 2024-02-07 Yongqiang Wang , Angelia Nedic

The best way to calculate statistics from medical data is to use the data of individual patients. In some settings, this data is difficult to obtain due to privacy restrictions. In Germany, for example, it is not possible to pool routine…

Machine Learning · Statistics 2020-03-18 Stefan Lenz , Harald Binder

Data silos, mainly caused by privacy and interoperability, significantly constrain collaborations among different organizations with similar data for the same purpose. Distributed learning based on divide-and-conquer provides a promising…

Machine Learning · Computer Science 2023-09-11 Di Wang , Xiaotong Liu , Shao-Bo Lin , Ding-Xuan Zhou

Deep learning with medical data often requires larger samples sizes than are available at single providers. While data sharing among institutions is desirable to train more accurate and sophisticated models, it can lead to severe privacy…

Machine Learning · Computer Science 2018-12-05 Brett K. Beaulieu-Jones , William Yuan , Samuel G. Finlayson , Zhiwei Steven Wu

A commonly used method to protect user privacy in data collection is to perform randomized perturbation on user's real data before collection so that aggregated statistics can still be inferred without endangering secrets held by…

Social and Information Networks · Computer Science 2019-09-04 Aria Rezaei , Jie Gao

When training a machine learning model, it is standard procedure for the researcher to have full knowledge of both the data and model. However, this engenders a lack of trust between data owners and data scientists. Data owners are…

Cryptography and Security · Computer Science 2020-09-24 Will Abramson , Adam James Hall , Pavlos Papadopoulos , Nikolaos Pitropakis , William J Buchanan

Given a collection of vectors $x^{(1)},\dots,x^{(n)} \in \{0,1\}^d$, the selection problem asks to report the index of an "approximately largest" entry in $x=\sum_{j=1}^n x^{(j)}$. Selection abstracts a host of problems--in machine learning…

Cryptography and Security · Computer Science 2023-06-09 Ivan Damgård , Hannah Keller , Boel Nelson , Claudio Orlandi , Rasmus Pagh
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