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The work discusses the use of machine learning algorithms for anomaly detection in medical image analysis and how the performance of these algorithms depends on the number of annotators and the quality of labels. To address the issue of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Hieu H. Pham , Khiem H. Le , Tuan V. Tran , Ha Q. Nguyen

Accurate ground truth estimation in medical screening programs often relies on coalitions of experts and peer second opinions. Algorithms that efficiently aggregate noisy annotations can enhance screening workflows, particularly when data…

Machine Learning · Computer Science 2025-10-07 Tim Bary , Tiffanie Godelaine , Axel Abels , Benoît Macq

Deep learning-based object detectors have achieved impressive performance in microscopy imaging, yet their confidence estimates often lack calibration, limiting their reliability for biomedical applications. In this work, we introduce a new…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Francesco Campi , Lucrezia Tondo , Ekin Karabati , Johannes Betge , Marie Piraud

Many machine learning systems today are trained on large amounts of human-annotated data. Data annotation tasks that require a high level of competency make data acquisition expensive, while the resulting labels are often subjective,…

Machine Learning · Computer Science 2020-04-08 Emmanouil Antonios Platanios , Maruan Al-Shedivat , Eric Xing , Tom Mitchell

Recent years have seen increasing use of supervised learning methods for segmentation tasks. However, the predictive performance of these algorithms depends on the quality of labels. This problem is particularly pertinent in the medical…

Computer Vision and Pattern Recognition · Computer Science 2020-10-26 Le Zhang , Ryutaro Tanno , Mou-Cheng Xu , Chen Jin , Joseph Jacob , Olga Ciccarelli , Frederik Barkhof , Daniel C. Alexander

The predictive performance of supervised learning algorithms depends on the quality of labels. In a typical label collection process, multiple annotators provide subjective noisy estimates of the "truth" under the influence of their varying…

Machine Learning · Computer Science 2019-06-18 Ryutaro Tanno , Ardavan Saeedi , Swami Sankaranarayanan , Daniel C. Alexander , Nathan Silberman

The annotation of domain experts is important for some medical applications where the objective ground truth is ambiguous to define, e.g., the rehabilitation for some chronic diseases, and the prescreening of some musculoskeletal…

Machine Learning · Computer Science 2023-03-10 Chongyang Wang , Yuan Gao , Chenyou Fan , Junjie Hu , Tin Lun Lam , Nicholas D. Lane , Nadia Bianchi-Berthouze

Recent advances in deep learning algorithms have led to significant benefits for solving many medical image analysis problems. Training deep learning models commonly requires large datasets with expert-labeled annotations. However,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , Stephanie Wichuk , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

Multi-rater annotations commonly occur when medical images are independently annotated by multiple experts (raters). In this paper, we tackle two challenges arisen in multi-rater annotations for medical image segmentation (called ambiguous…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Jinhong Wang , Yi Cheng , Jintai Chen , Hongxia Xu , Danny Chen , Jian Wu

Medical image segmentation annotations suffer from inter- and intra-observer variations even among experts due to intrinsic differences in human annotators and ambiguous boundaries. Leveraging a collection of annotators' opinions for an…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Zahra Mirikharaji , Kumar Abhishek , Saeed Izadi , Ghassan Hamarneh

Supervised machine learning assumes that labeled data provide accurate measurements of the concepts models are meant to learn. Yet in practice, human labeling introduces systematic variation arising from ambiguous items, divergent…

Methodology · Statistics 2026-04-10 Robert Chew , Stephanie Eckman , Christoph Kern , Frauke Kreuter

Solving complex classification tasks using deep neural networks typically requires large amounts of annotated data. However, corresponding class labels are noisy when provided by error-prone annotators, e.g., crowdworkers. Training standard…

Machine Learning · Computer Science 2023-10-25 Marek Herde , Denis Huseljic , Bernhard Sick

Current deep learning paradigms largely benefit from the tremendous amount of annotated data. However, the quality of the annotations often varies among labelers. Multi-observer studies have been conducted to study these annotation…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Xiaosong Wang , Ziyue Xu , Dong Yang , Leo Tam , Holger Roth , Daguang Xu

Data lies at the core of modern deep learning. The impressive performance of supervised learning is built upon a base of massive accurately labeled data. However, in some real-world applications, accurate labeling might not be viable;…

Healthcare data suffers from both noise and lack of ground truth. The cost of data increases as it is cleaned and annotated in healthcare. Unlike other data sets, medical data annotation, which is critical to accurate ground truth, requires…

Signal Processing · Electrical Eng. & Systems 2020-10-13 V. Ratna Saripalli , Gopal Avinash , Dibyajyoti Pati , Michael Potter , Charles W. Anderson

Deep-learning-based pipelines have shown the potential to revolutionalize microscopy image diagnostics by providing visual augmentations to a trained pathology expert. However, to match human performance, the methods rely on the…

The reliability of supervised machine learning systems depends on the accuracy and availability of ground truth labels. However, the process of human annotation, being prone to error, introduces the potential for noisy labels, which can…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 David Tschirschwitz , Christian Benz , Morris Florek , Henrik Norderhus , Benno Stein , Volker Rodehorst

Probably yes. -- Supervised Deep Learning dominates performance scores for many computer vision tasks and defines the state-of-the-art. However, medical image analysis lags behind natural image applications. One of the many reasons is the…

Computer Vision and Pattern Recognition · Computer Science 2021-08-02 Samuel Budd , Thomas Day , John Simpson , Karen Lloyd , Jacqueline Matthew , Emily Skelton , Reza Razavi , Bernhard Kainz

High-quality data is necessary for modern machine learning. However, the acquisition of such data is difficult due to noisy and ambiguous annotations of humans. The aggregation of such annotations to determine the label of an image leads to…

Computer Vision and Pattern Recognition · Computer Science 2022-11-07 Lars Schmarje , Vasco Grossmann , Claudius Zelenka , Sabine Dippel , Rainer Kiko , Mariusz Oszust , Matti Pastell , Jenny Stracke , Anna Valros , Nina Volkmann , Reinhard Koch

Universal lesion detection has great value for clinical practice as it aims to detect various types of lesions in multiple organs on medical images. Deep learning methods have shown promising results, but demanding large volumes of…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Xiaoyu Bai , Benteng Ma , Changyang Li , Yong Xia
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