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Related papers: SynthStrip: Skull-Stripping for Any Brain Image

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Skull-stripping is the removal of background and non-brain anatomical features from brain images. While many skull-stripping tools exist, few target pediatric populations. With the emergence of multi-institutional pediatric data acquisition…

Image and Video Processing · Electrical Eng. & Systems 2025-12-05 William Kelley , Nathan Ngo , Adrian V. Dalca , Bruce Fischl , Lilla Zöllei , Malte Hoffmann

Skull stripping magnetic resonance images (MRI) of the human brain is an important process in many image processing techniques, such as automatic segmentation of brain structures. Numerous methods have been developed to perform this task,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-16 Hjalti Thrastarson , Lotta M. Ellingsen

Skull-stripping separates the skull region of the head from the soft brain tissues. In many cases of brain image analysis, this is an essential preprocessing step in order to improve the final result. This is true for both registration and…

Computer Vision and Pattern Recognition · Computer Science 2012-04-03 Stefan Bauer , Lutz-P. Nolte , Mauricio Reyes

Retrospective analysis of brain MRI scans acquired in the clinic has the potential to enable neuroimaging studies with sample sizes much larger than those found in research datasets. However, analysing such clinical images "in the wild" is…

Image and Video Processing · Electrical Eng. & Systems 2023-01-06 Benjamin Billot , Magdamo Colin , Sean E. Arnold , Sudeshna Das , Juan. E. Iglesias

Most existing algorithms for automatic 3D morphometry of human brain MRI scans are designed for data with near-isotropic voxels at approximately 1 mm resolution, and frequently have contrast constraints as well - typically requiring T1…

Image and Video Processing · Electrical Eng. & Systems 2020-12-25 Juan Eugenio Iglesias , Benjamin Billot , Yael Balbastre , Azadeh Tabari , John Conklin , Daniel C. Alexander , Polina Golland , Brian L. Edlow , Bruce Fischl

Brain extraction (skull stripping) is a challenging problem in neuroimaging. It is due to the variability in conditions from data acquisition or abnormalities in images, making brain morphology and intensity characteristics changeable and…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Duy H. M. Nguyen , Duy M. Nguyen , Mai T. N. Truong , Thu Nguyen , Khanh T. Tran , Nguyen A. Triet , Pham T. Bao , Binh T. Nguyen

Skull-stripping methods aim to remove the non-brain tissue from acquisition of brain scans in magnetic resonance (MR) imaging. Although several methods sharing this common purpose have been presented in literature, they all suffer from the…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 Gabriele Valvano , Nicola Martini , Andrea Leo , Gianmarco Santini , Daniele Della Latta , Emiliano Ricciardi , Dante Chiappino

Despite advances in data augmentation and transfer learning, convolutional neural networks (CNNs) difficultly generalise to unseen domains. When segmenting brain scans, CNNs are highly sensitive to changes in resolution and contrast: even…

Image and Video Processing · Electrical Eng. & Systems 2023-03-01 Benjamin Billot , Douglas N. Greve , Oula Puonti , Axel Thielscher , Koen Van Leemput , Bruce Fischl , Adrian V. Dalca , Juan Eugenio Iglesias

Skullstripping is defined as the task of segmenting brain tissue from a full head magnetic resonance image~(MRI). It is a critical component in neuroimage processing pipelines. Downstream deformable registration and whole brain segmentation…

Computer Vision and Pattern Recognition · Computer Science 2019-04-30 Amod Jog , P. Ellen Grant , Joseph L. Jacobson , Andre van der Kouwe , Ernesta M. Meintjes , Bruce Fischl , Lilla Zöllei

We present a deep learning strategy that enables, for the first time, contrast-agnostic semantic segmentation of completely unpreprocessed brain MRI scans, without requiring additional training or fine-tuning for new modalities. Classical…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Benjamin Billot , Douglas Greve , Koen Van Leemput , Bruce Fischl , Juan Eugenio Iglesias , Adrian V. Dalca

Every year, millions of brain MRI scans are acquired in hospitals, which is a figure considerably larger than the size of any research dataset. Therefore, the ability to analyse such scans could transform neuroimaging research. Yet, their…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Benjamin Billot , Colin Magdamo , You Cheng , Steven E. Arnold , Sudeshna Das , Juan. E. Iglesias

Brain extraction is a fundamental step for most brain imaging studies. In this paper, we investigate the problem of skull stripping and propose complementary segmentation networks (CompNets) to accurately extract the brain from T1-weighted…

Computer Vision and Pattern Recognition · Computer Science 2018-10-11 Raunak Dey , Yi Hong

Deployment complexity and specialized hardware requirements hinder the adoption of deep learning models in neuroimaging. We present MindGrab, a lightweight, fully convolutional model for volumetric skull stripping across all imaging…

Image and Video Processing · Electrical Eng. & Systems 2026-01-30 Armina Fani , Mike Doan , Isabelle Le , Alex Fedorov , Malte Hoffmann , Chris Rorden , Sergey Plis

Whole brain extraction, also known as skull stripping, is a process in neuroimaging in which non-brain tissue such as skull, eyeballs, skin, etc. are removed from neuroimages. Skull striping is a preliminary step in presurgical planning,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-05 Sara Ranjbar , Kyle W. Singleton , Lee Curtin , Cassandra R. Rickertsen , Lisa E. Paulson , Leland S. Hu , J. Ross Mitchell , Kristin R. Swanson

We introduce a strategy for learning image registration without acquired imaging data, producing powerful networks agnostic to contrast introduced by magnetic resonance imaging (MRI). While classical registration methods accurately estimate…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Malte Hoffmann , Benjamin Billot , Douglas N. Greve , Juan Eugenio Iglesias , Bruce Fischl , Adrian V. Dalca

While many skull stripping algorithms have been developed for multi-modal and multi-species cases, there is still a lack of a fundamentally generalizable approach. We present PUMBA(PUrely synthetic Multimodal/species invariant Brain…

Image and Video Processing · Electrical Eng. & Systems 2025-05-13 Jong Sung Park , Juhyung Ha , Siddhesh Thakur , Alexandra Badea , Spyridon Bakas , Eleftherios Garyfallidis

The bottleneck of convolutional neural networks (CNN) for medical imaging is the number of annotated data required for training. Manual segmentation is considered to be the "gold-standard". However, medical imaging datasets with expert…

Image and Video Processing · Electrical Eng. & Systems 2017-10-24 Oeslle Lucena , Roberto Souza , Letícia Rittner , Richard Frayne , Roberto Lotufo

Objectives: Present a novel deep learning-based skull stripping algorithm for magnetic resonance imaging (MRI) that works directly in the information rich k-space. Materials and Methods: Using two datasets from different institutions with a…

Image and Video Processing · Electrical Eng. & Systems 2023-07-10 Moritz Rempe , Florian Mentzel , Kelsey L. Pomykala , Johannes Haubold , Felix Nensa , Kevin Kröninger , Jan Egger , Jens Kleesiek

Current deep learning-based approaches to lesion segmentation in neuroimaging often depend on high-resolution images and extensive annotated data, limiting clinical applicability. This paper introduces a novel synthetic data framework…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Liam Chalcroft , Ioannis Pappas , Cathy J. Price , John Ashburner

Whole-brain surface extraction is an essential topic in medical imaging systems as it provides neurosurgeons with a broader view of surgical planning and abnormality detection. To solve the problem confronted in current deep learning skull…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 Heng Fang , Xi Yang , Taichi Kin , Takeo Igarashi
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