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Surface-enhanced Raman spectroscopy (SERS) is a sensitive label-free optical method that can provide fingerprint Raman spectra of biomolecules such as DNA, amino acids and proteins. While SERS of single DNA molecule has been recently…

Ag nanorod arrays/dielectrics/mirror-structured multilayer thin-film are well known, highly sensitive surface-enhanced Raman scattering (SERS) substrates that enhance the Raman scattering cross-section by the interference of light. However,…

Applied Physics · Physics 2020-10-08 Samir Kumar , Misa Kanagawa , Kyoko Namura , Takao Fukuoka , Motofumi Suzuki

The Raman scattering of light by molecular vibrations offers a powerful technique to 'fingerprint' molecules via their internal bonds and symmetries. Since Raman scattering is weak, methods to enhance, direct and harness it are highly…

Nanofibers functionalized by metal nanostructures and particles are exploited as effective flexible substrates for SERS analysis. Their complex three-dimensional structure may provide Raman signals enhanced by orders of magnitude compared…

Materials Science · Physics 2016-03-16 A. Camposeo , D. Spadaro , D. Magrì , M. Moffa , P. G. Gucciardi , L. Persano , O. M. Maragò , D. Pisignano

Dynamic surface-enhanced Raman spectroscopy (SERS) is nowadays one of the most interesting applications of SERS, in particular for single molecule studies. In fact, it enables the study of real-time processes at the molecular level. This…

Surface-enhanced Raman spectroscopy (SERS) demands reliable, high enhancement substrates in order to be used in different fields of application. Here, we introduce freestanding porous gold membranes (PAuM) as easy to produce, scalable,…

Waveguide-enhanced Raman spectroscopy (WERS) is a promising technique for sensitive and selective detection of chemicals in a compact chip-scale platform. Coupling light on and off the sensor chip with fibers however presents challenges…

Applied Physics · Physics 2020-05-05 Derek M. Kita , Jérôme Michon , Juejun Hu

Wearable sensors have become ubiquitous thanks to a variety of health tracking features. The resulting continuous and longitudinal measurements from everyday life generate large volumes of data; however, making sense of these observations…

Volatile organic compounds (VOCs) are valuable health indicators, with synthetic breath biomarkers offering rapid and disease specific diagnostics. However, their <100 ppb level exhalation requires mass spectrometry, limiting clinical…

Even after more than four decades of rapid-pace advances, the adoption of Surface-Enhanced Raman Scattering (SERS) remains limited, due to the difficulties in fabrication of effective and affordable nanostructured surfaces or templates.…

The long-range action of surface-enhanced Raman scattering (SERS) is probed via distance-dependent measurements of molecular Raman spectra. To this end, identical SERS substrates composed of irregular silver nanoisland arrays were covered…

Materials Science · Physics 2015-06-12 V. I. Kukushkin , A. B. Van'kov , I. V. Kukushkin

Continuous glucose monitoring (CGM) is vital for diabetes care, but current systems rely on invasive implants or electrochemical sensors that often cause discomfort and skin irritation. Non-invasive alternatives remain limited by low…

Single-molecule detection with chemical specificity is a powerful and much desired tool for biology, chemistry, physics, and sensing technologies. Surface-enhanced spectroscopies enable single molecule studies, yet reliable substrates of…

Mesoscale and Nanoscale Physics · Physics 2008-02-22 D. R. Ward , N. K. Grady , C. S. Levin , N. J. Halas , Y. Wu , P. Nordlander , D. Natelson

The concern on human health is often overseen while wearable technologies attract exploding interests. Mainly due to the extreme proximity or a direct physical contact to the human skin, wearable communications devices are acknowledged to…

Signal Processing · Electrical Eng. & Systems 2019-12-12 Seungmo Kim , Yakub Sharif , Imtiaz Nasim

Surface-enhanced Raman spectroscopy (SERS) is a sensitive vibrational spectroscopy technique that can enable fast and non-destructive detection of trace molecules. SERS substrates are critical for the advancement of the SERS application. By…

Materials Science · Physics 2020-11-30 Samir Kumar , Takao Fukuoka , Kyoko Namura , Motofumi Suzuki

We demonstrated a highly sensitive, waferscale, highly uniform plasmonic nanomushroom substrate based on plastic for nakedeye plasmonic colorimetry and surface enhanced Raman spectroscopy (SERS). We gave it the name FlexBrite. The dualmode…

Electronic skin, a class of wearable electronic sensors that mimic the functionalities of human skin, has made remarkable success in applications including health monitoring, human-machine interaction and electronic-biological interfaces.…

A plasmonic nanostructure-based substrate, serving as a surface-enhanced Raman scattering (SERS) substrate, enhances the Raman scattering of molecules. By employing an electron beam lithography followed by our recently developed…

We present a hybrid surface-enhanced Raman spectroscopy (SERS) platform based on dielectric silicon metasurfaces integrated with functionalized graphene for the selective detection of biomolecules such as prolactin and SARS-CoV-2…

Flexible and epidermal sensing devices are becoming vital to enable precision medicine and telemonitoring systems. The NFC (Near Field Communication) protocol is also becoming increasingly important for this application since it is embedded…