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In the field of evolutionary multi-objective optimization, the approximation of the Pareto front (PF) is achieved by utilizing a collection of representative candidate solutions that exhibit desirable convergence and diversity. Although…
Currently in HDR brachytherapy planning, a manual fine-tuning of an objective function is necessary to obtain case-specific valid plans. This study intends to facilitate this process by proposing a patient-specific inverse planning…
Numerous multi-objective optimization problems encounter with a number of fitness functions to be simultaneously optimized of which their mutual preferences are not inherently known. Suffering from the lack of underlying generative models,…
The prospect of assistive robots aiding in object organization has always been compelling. In an image-goal setting, the robot rearranges the current scene to match the single image captured from the goal scene. The key to an image-goal…
Recent decades have witnessed great advancements in multiobjective evolutionary algorithms (MOEAs) for multiobjective optimization problems (MOPs). However, these progressively improved MOEAs have not necessarily been equipped with scalable…
Multi-objective Bayesian optimization has been widely adopted in scientific experiment design, including drug discovery and hyperparameter optimization. In practice, regulatory or safety concerns often impose additional thresholds on…
Multi-objective optimisation using BRIGHT has proven insightful and effective in prostate cancer brachytherapy treatment planning. BRachytherapy via artificially Intelligent GOMEA-Heuristic based Treatment planning (BRIGHT) generates…
Large language models (LLMs) are increasingly deployed in real-world applications that require careful balancing of multiple, often conflicting, objectives, such as informativeness versus conciseness, or helpfulness versus creativity.…
Multi-objective optimization (MOO) has received growing attention in applications that require learning under multiple criteria. However, the existing MOO formulations do not explicitly account for distributional shifts in the data. We…
For predicting cancer survival outcomes, standard approaches in clinical research are often based on two main modalities: pathology images for observing cell morphology features, and genomic (e.g., bulk RNA-seq) for quantifying gene…
Many real-world optimization problems such as engineering design can be eventually modeled as the corresponding multiobjective optimization problems (MOPs) which must be solved to obtain approximate Pareto optimal fronts. Multiobjective…
In solving multi-modal, multi-objective optimization problems (MMOPs), the objective is not only to find a good representation of the Pareto-optimal front (PF) in the objective space but also to find all equivalent Pareto-optimal subsets…
In multi-objective black-box optimization, the goal is typically to find solutions that optimize a set of $T$ black-box objective functions, $f_1, \ldots f_T$, simultaneously. Traditional approaches often seek a single Pareto-optimal set…
Evolutionary optimization algorithms often face defects and limitations that complicate the evolution processes or even prevent them from reaching the global optimum. A notable constraint pertains to the considerable quantity of function…
The Gene-pool Optimal Mixing EA (GOMEA) family of EAs offers a specific means to exploit problem-specific knowledge through linkage learning, i.e., inter-variable dependency detection, expressed using subsets of variables, that should…
Genetic studies have identified associations between gene mutations and clear cell renal cell carcinoma (ccRCC). Because the complete gene mutational landscape cannot be characterized through biopsy and sequencing assays for each patient,…
Working with complex, high-level MOEA meta-models such as Multiobjec-tive Optimization Hierarchic Genetic Strategy (MO-mHGS) with multi-deme support usually requires dedicated implementation and configuration for each internal (single-deme)…
Choices in scientific research and management require balancing multiple, often competing objectives.Multiple-objective optimization (MOO) provides a unifying framework for solving multiple objective problems. Model selection is a critical…
Automatically tuning software configuration for optimizing a single performance attribute (e.g., minimizing latency) is not trivial, due to the nature of the configuration systems (e.g., complex landscape and expensive measurement). To deal…
When tuning software configuration for better performance (e.g., latency or throughput), an important issue that many optimizers face is the presence of local optimum traps, compounded by a highly rugged configuration landscape and…