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Multi-objective evolutionary algorithms (MOEAs) are widely used to solve multi-objective optimization problems. The algorithms rely on setting appropriate parameters to find good solutions. However, this parameter tuning could be very…

Neural and Evolutionary Computing · Computer Science 2022-11-18 Remco Coppens , Robbert Reijnen , Yingqian Zhang , Laurens Bliek , Berend Steenhuisen

This paper introduces the inverse modeling constrained multi-objective evolutionary algorithm based on decomposition (IM-C-MOEA/D) for addressing constrained real-world optimization problems. Our research builds upon the advancements made…

Neural and Evolutionary Computing · Computer Science 2024-10-28 Lucas R. C. Farias , Aluizio F. R. Araújo

Domination-based multi-objective (MO) evolutionary algorithms (EAs) are today arguably the most frequently used type of MOEA. These methods however stagnate when the majority of the population becomes non-dominated, preventing convergence…

Neural and Evolutionary Computing · Computer Science 2020-04-13 S. C. Maree , T. Alderliesten , P. A. N. Bosman

Multi-objective optimization problems whose objectives have different evaluation costs are commonly seen in the real world. Such problems are now known as multi-objective optimization problems with heterogeneous objectives (HE-MOPs). So…

Neural and Evolutionary Computing · Computer Science 2022-08-26 Xilu Wang , Yaochu Jin , Sebastian Schmitt , Markus Olhofer

This study modifies the Covariance Matrix Adaptation Evolution Strategy (CMA-ES) algorithm for multi-modal optimization problems. The enhancements focus on addressing the challenges of multiple global minima, improving the algorithm's…

Neural and Evolutionary Computing · Computer Science 2024-07-02 Wathsala Karunarathne , Indu Bala , Dikshit Chauhan , Matthew Roughan , Lewis Mitchell

Multi-Objective Evolutionary Algorithms (MOEAs) have been proved efficient to deal with Multi-objective Optimization Problems (MOPs). Until now tens of MOEAs have been proposed. The unified mode would provide a more systematic approach to…

Neural and Evolutionary Computing · Computer Science 2011-02-01 Bojin Zheng , Yuanxiang Li

High-dose-rate (HDR) brachytherapy plays a critical role in the treatment of locally advanced cervical cancer but remains highly dependent on manual treatment planning expertise. The objective of this study is to develop a fully automated…

Clinical decision-making reflects diverse strategies shaped by regional patient populations and institutional protocols. However, most existing medical artificial intelligence (AI) models are trained on highly prevalent data patterns, which…

Radiotherapy planning is a critical aspect of cancer treatment, where the optimal selection of beam directions and dose distributions significantly impacts treatment efficacy and patient outcomes. Traditionally, this process involves…

Medical Physics · Physics 2023-12-05 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

Parameter control has succeeded in accelerating the convergence process of evolutionary algorithms. While empirical and theoretical studies have shed light on the behavior of algorithms for single-objective optimization, little is known…

Neural and Evolutionary Computing · Computer Science 2023-05-09 Furong Ye , Frank Neumann , Jacob de Nobel , Aneta Neumann , Thomas Bäck

In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…

Medical Physics · Physics 2016-01-06 Yu Yang , Bin Dong , Zaiwen Wen

Designing a transcranial electrical stimulation (TES) strategy requires considering multiple objectives, such as intensity in the target area, focality, stimulation depth, and avoidance zone, which are often mutually exclusive. A…

Quantitative Methods · Quantitative Biology 2023-09-13 Mo Wang , Kexin Lou , Zeming Liu , Pengfei Wei , Quanying Liu

Beam orientation optimization (BOO) is a key component in the process of IMRT treatment planning. It determines to what degree one can achieve a good treatment plan quality in the subsequent plan optimization process. In this paper, we have…

Medical Physics · Physics 2015-05-27 Xun Jia , Chunhua Men , Yifei Lou , Steve B. Jiang

Software configuration tuning is essential for optimizing a given performance objective (e.g., minimizing latency). Yet, due to the software's intrinsically complex configuration landscape and expensive measurement, there has been a rather…

Software Engineering · Computer Science 2024-03-18 Pengzhou Chen , Tao Chen , Miqing Li

Even if a Multi-modal Multi-Objective Evolutionary Algorithm (MMOEA) is designed to find solutions well spread over all locally optimal approximation sets of a Multi-modal Multi-objective Optimization Problem (MMOP), there is a risk that…

Neural and Evolutionary Computing · Computer Science 2022-07-05 Renzo J. Scholman , Anton Bouter , Leah R. M. Dickhoff , Tanja Alderliesten , Peter A. N. Bosman

Optimal Mixing (OM) is a variation operator that integrates local search with genetic recombination. EAs with OM are capable of state-of-the-art optimization in discrete spaces, offering significant advantages over classic…

Neural and Evolutionary Computing · Computer Science 2025-06-19 Anton Bouter , Dirk Thierens , Peter A. N. Bosman

In a treatment plan optimization problem for radiotherapy, a clinically acceptable plan is usually generated by an optimization process with weighting factors or reference doses adjusted for organs. Recent discoveries indicate that…

Medical Physics · Physics 2012-10-29 Masoud Zarepisheh , Andres F. Uribe-Sanchez , Nan Li , Xun Jia , Steve B. Jiang

Bayesian Optimization (BO) is a powerful tool for optimizing expensive black-box objective functions. While extensive research has been conducted on the single-objective optimization problem, the multi-objective optimization problem remains…

Machine Learning · Computer Science 2025-10-27 Lam Ngo , Huong Ha , Jeffrey Chan , Hongyu Zhang

We propose a surrogate-assisted reference vector adaptation (SRVA) method to solve expensive multi- and many-objective optimization problems with various Pareto front shapes. SRVA is coupled with a multi-objective Bayesian optimization…

Machine Learning · Computer Science 2021-10-12 Nobuo Namura

Migration has been a universal phenomenon, which brings opportunities as well as challenges for global development. As the number of migrants (e.g., refugees) increases rapidly in recent years, a key challenge faced by each country is the…

Neural and Evolutionary Computing · Computer Science 2024-09-10 Dan-Xuan Liu , Yu-Ran Gu , Chao Qian , Xin Mu , Ke Tang