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This paper introduces a new framework for recovering causal graphs from observational data, leveraging the observation that the distribution of an effect, conditioned on its causes, remains invariant to changes in the prior distribution of…

Machine Learning · Computer Science 2026-02-04 Nang Hung Nguyen , Phi Le Nguyen , Thao Nguyen Truong , Trong Nghia Hoang , Masashi Sugiyama

Predicting the effect of interventions with many possible variations, e.g., therapeutic content that affects mental health outcomes or an earnings call transcript that drives movement in share price, is useful across several domains.…

Machine Learning · Computer Science 2026-05-27 Nikita Dhawan , Arnav Paruthi , Andrew Kim , Lovedeep Gondara , Jekaterina Novikova , Chris J. Maddison

Response-adaptive allocation designs refer to a class of designs where the probability an observation is assigned to a treatment is changed throughout an experiment based on the accrued responses. Such procedures result in random treatment…

Methodology · Statistics 2022-08-04 Adam Lane

Data can be collected in scientific studies via a controlled experiment or passive observation. Big data is often collected in a passive way, e.g. from social media. In studies of causation great efforts are made to guard against bias and…

Methodology · Statistics 2018-11-21 Elena Pesce , Eva Riccomagno , Henry P. Wynn

This article focuses on the estimation and design aspects of a bivariate collocated cokriging experiment. For a large class of covariance matrices, a linear dependency criterion is identified, which allows the best linear unbiased estimator…

Methodology · Statistics 2022-03-15 Subhadra Dasgupta , Siuli Mukhopadhyay , Jonathan Keith

We consider nonregular fractions of factorial experiments for a class of linear models. These models have a common general mean and main effects, however they may have different 2-factor interactions. Here we assume for simplicity that…

Computation · Statistics 2019-11-11 Shrabanti Chowdhury , Joshua Lukemire , Abhyuday Mandal

Many high dimensional and high-throughput biological datasets have complex sample correlation structures, which include longitudinal and multiple tissue data, as well as data with multiple treatment conditions or related individuals. These…

Methodology · Statistics 2018-08-20 Chris McKennan , Dan Nicolae

Design-based frameworks of uncertainty are frequently used in settings where the treatment is (conditionally) randomly assigned. This paper develops a design-based framework suitable for analyzing quasi-experimental settings in the social…

Econometrics · Economics 2025-06-17 Ashesh Rambachan , Jonathan Roth

Causal discovery serves a pivotal role in mitigating model uncertainty through recovering the underlying causal mechanisms among variables. In many practical domains, such as healthcare, access to the data gathered by individual entities is…

Machine Learning · Computer Science 2024-02-13 Amin Abyaneh , Nino Scherrer , Patrick Schwab , Stefan Bauer , Bernhard Schölkopf , Arash Mehrjou

Identifying causal treatment (or exposure) effects in observational studies requires the data to satisfy the unconfoundedness assumption which is not testable using the observed data. With sensitivity analysis, one can determine how the…

Methodology · Statistics 2023-01-31 Yang Ou , Lu Tang , Chung-Chou H. Chang

Small sample sizes are common in many disciplines, which necessitates pooling roughly similar datasets across multiple institutions to study weak but relevant associations between images and disease outcomes. Such data often manifest…

Machine Learning · Computer Science 2024-11-19 Sotirios Panagiotis Chytas , Vishnu Suresh Lokhande , Peiran Li , Vikas Singh

Causal inference is a critical research topic across many domains, such as statistics, computer science, education, public policy and economics, for decades. Nowadays, estimating causal effect from observational data has become an appealing…

Methodology · Statistics 2020-02-10 Liuyi Yao , Zhixuan Chu , Sheng Li , Yaliang Li , Jing Gao , Aidong Zhang

Data generated from a system of interest typically consists of measurements from an ensemble of subjects across multiple response and covariate features, and is naturally represented by one response-matrix against one covariate-matrix.…

Methodology · Statistics 2018-07-04 Hsieh Fushing , Shan-Yu Liu , Yin-Chen Hsieh , Brenda McCowan

Method validation and study design in causal inference rely on synthetic data with known counterfactuals. Existing simulators trade off distributional realism, the ability to capture mixed-type and multimodal tabular data, against causal…

Methodology · Statistics 2026-03-05 Qi Zhang , Harsh Parikh , Ashley Naimi , Razieh Nabi , Christopher Kim , Timothy Lash

Motivated by the challenges in analyzing gut microbiome and metagenomic data, this work aims to tackle the issue of measurement errors in high-dimensional regression models that involve compositional covariates. This paper marks a…

Methodology · Statistics 2024-09-13 Huali Zhao , Tianying Wang

Inferring causal effects of a treatment, intervention or policy from observational data is central to many applications. However, state-of-the-art methods for causal inference seldom consider the possibility that covariates have missing…

Methodology · Statistics 2020-02-26 Imke Mayer , Julie Josse , Félix Raimundo , Jean-Philippe Vert

Modern network data analysis often involves analyzing network structures alongside covariate features to gain deeper insights into underlying patterns. However, traditional covariate-assisted statistical network models may not adequately…

Methodology · Statistics 2025-05-07 Peng Zhao , Yabo Niu

In recent years, many methods have been developed for detecting causal relationships in observational data. Some of them have the potential to tackle large data sets. However, these methods fail to discover a combined cause, i.e. a…

Artificial Intelligence · Computer Science 2015-10-16 Saisai Ma , Jiuyong Li , Lin Liu , Thuc Duy Le

This paper considers the problem of design-based inference for the average treatment effect in finely stratified experiments. Here, by "design-based'' we mean that the only source of uncertainty stems from the randomness in treatment…

Econometrics · Economics 2025-05-08 Yuehao Bai , Xun Huang , Joseph P. Romano , Azeem M. Shaikh , Max Tabord-Meehan

The inaccessibility of controlled randomized trials due to inherent constraints in many fields of science has been a fundamental issue in causal inference. In this paper, we focus on distinguishing the cause from effect in the bivariate…

Machine Learning · Statistics 2021-02-23 Jean-Francois Ton , Dino Sejdinovic , Kenji Fukumizu
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