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Alzheimer's dementia (AD) is of increasing concern as populations achieve longer lifespans. Many of the recent failed AD clinical trials recruiting cognitively intact individuals had a low number of AD events and were thus underpowered.…

Methodology · Statistics 2025-03-21 Julia Gallini , Zach Baucom , Yorghos Tripodis

Counterfactual generation offers a principled framework for simulating hypothetical changes in medical imaging, with potential applications in understanding disease mechanisms and generating physiologically plausible data. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Pengwei Sun , Wei Peng , Lun Yu Li , Yixin Wang , Kilian M. Pohl

Medical imaging plays a critical role in various clinical applications. However, due to multiple considerations such as cost and risk, the acquisition of certain image modalities could be limited. To address this issue, many cross-modality…

Image and Video Processing · Electrical Eng. & Systems 2019-07-09 Dong Nie , Lei Xiang , Qian Wang , Dinggang Shen

Recent works show that Generative Adversarial Networks (GANs) can be successfully applied to chest X-ray data augmentation for lung disease recognition. However, the implausible and distorted pathology features generated from the less than…

Image and Video Processing · Electrical Eng. & Systems 2020-01-23 Yunyan Xing , Zongyuan Ge , Rui Zeng , Dwarikanath Mahapatra , Jarrel Seah , Meng Law , Tom Drummond

Whilst face recognition applications are becoming increasingly prevalent within our daily lives, leading approaches in the field still suffer from performance bias to the detriment of some racial profiles within society. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Seyma Yucer , Samet Akçay , Noura Al-Moubayed , Toby P. Breckon

The GANs promote an adversarive game to approximate complex and jointed example probability. The networks driven by noise generate fake examples to approximate realistic data distributions. Later the conditional GAN merges prior-conditions…

Computer Vision and Pattern Recognition · Computer Science 2017-07-18 Meng Wang , Huafeng Li , Fang Li

We propose a higher-level associative memory for learning adversarial networks. Generative adversarial network (GAN) framework has a discriminator and a generator network. The generator (G) maps white noise (z) to data samples while the…

Machine Learning · Computer Science 2016-11-23 Tarik Arici , Asli Celikyilmaz

Generative Adversarial Networks (GANs) can help overcome data scarcity in computer vision tasks by generating additional training samples. In this work, we explore generative data augmentation in two low-resource domains: Bangla handwritten…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Md. Sohanuzzaman Soad , Mahady Al Hady , S M Rafiuddin Rifat , Sudip Ghose

Adversarial learning methods are a promising approach to training robust deep networks, and can generate complex samples across diverse domains. They also can improve recognition despite the presence of domain shift or dataset bias: several…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Eric Tzeng , Judy Hoffman , Kate Saenko , Trevor Darrell

The automatic early diagnosis of prodromal stages of Alzheimer's disease is of great relevance for patient treatment to improve quality of life. We address this problem as a multi-modal classification task. Multi-modal data provides richer…

In medical imaging, image synthesis is the estimation process of one image (sequence, modality) from another image (sequence, modality). Since images with different modalities provide diverse biomarkers and capture various features,…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Firoozeh Shomal Zadeh , Sevda Molani , Maysam Orouskhani , Marziyeh Rezaei , Mehrzad Shafiei , Hossein Abbasi

Generative Adversarial Networks (GAN) have attracted much research attention recently, leading to impressive results for natural image generation. However, to date little success was observed in using GAN generated images for improving…

Computer Vision and Pattern Recognition · Computer Science 2017-11-15 Xinlong Wang , Zhipeng Man , Mingyu You , Chunhua Shen

Deep Neural Networks (DNNs) show a significant impact on medical imaging. One significant problem with adopting DNNs for skin cancer classification is that the class frequencies in the existing datasets are imbalanced. This problem hinders…

Image and Video Processing · Electrical Eng. & Systems 2019-10-29 Ibrahim Saad Ali , Mamdouh Farouk Mohamed , Yousef Bassyouni Mahdy

Introspection of deep supervised predictive models trained on functional and structural brain imaging may uncover novel markers of Alzheimer's disease (AD). However, supervised training is prone to learning from spurious features (shortcut…

Machine Learning · Computer Science 2022-05-24 Alex Fedorov , Lei Wu , Tristan Sylvain , Margaux Luck , Thomas P. DeRamus , Dmitry Bleklov , Sergey M. Plis , Vince D. Calhoun

Alzheimer's disease (AD) is one of the most common public health issues the world is facing today. This disease has a high prevalence primarily in the elderly accompanying memory loss and cognitive decline. AD detection is a challenging…

Image and Video Processing · Electrical Eng. & Systems 2022-04-04 Zahraa Sh. Aaraji , Hawraa H. Abbas

Class imbalance occurs in many real-world applications, including image classification, where the number of images in each class differs significantly. With imbalanced data, the generative adversarial networks (GANs) leans to majority class…

Computer Vision and Pattern Recognition · Computer Science 2022-01-14 Yuchong Yao , Xiaohui Wangr , Yuanbang Ma , Han Fang , Jiaying Wei , Liyuan Chen , Ali Anaissi , Ali Braytee

Remarkable successes were made in Medical Image Classification (MIC) recently, mainly due to wide applications of convolutional neural networks (CNNs). However, adversarial examples (AEs) exhibited imperceptible similarity with raw data,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Shuai Li , Xiaoguang Ma , Shancheng Jiang , Lu Meng

The application of causal discovery to diseases like Alzheimer's (AD) is limited by the static graph assumptions of most methods; such models cannot account for an evolving pathophysiology, modulated by a latent disease pseudotime. We…

Applications · Statistics 2025-11-07 Natalia Glazman , Jyoti Mangal , Pedro Borges , Sebastien Ourselin , M. Jorge Cardoso

Adversarial Training (AT) is known as an effective approach to enhance the robustness of deep neural networks. Recently researchers notice that robust models with AT have good generative ability and can synthesize realistic images, while…

Machine Learning · Computer Science 2022-03-28 Yifei Wang , Yisen Wang , Jiansheng Yang , Zhouchen Lin

Image augmentations applied during training are crucial for the generalization performance of image classifiers. Therefore, a large body of research has focused on finding the optimal augmentation policy for a given task. Yet, RandAugment…

Machine Learning · Computer Science 2021-12-06 Arno Blaas , Xavier Suau , Jason Ramapuram , Nicholas Apostoloff , Luca Zappella