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Recent technological advances have made it possible to simultaneously measure multiple protein activities at the single cell level. With such data collected under different stimulatory or inhibitory conditions, it is possible to infer the…

Applications · Statistics 2011-08-04 Ruiyan Luo , Hongyu Zhao

This paper introduces a Bayesian framework that combines Markov chain Monte Carlo (MCMC) sampling, dimensionality reduction, and neural density estimation to efficiently handle inverse problems that (i) must be solved multiple times, and…

Computational Engineering, Finance, and Science · Computer Science 2026-02-24 Giacomo Bottacini , Matteo Torzoni , Andrea Manzoni

We present a method for detection of weak continuous signals from sources in binary systems via the incoherent combination of many "short" coherently-analyzed segments. The main focus of the work is on the construction of a metric on the…

General Relativity and Quantum Cosmology · Physics 2015-05-30 Chris Messenger

In this paper we consider the estimation of unknown parameters in Bayesian inverse problems. In most cases of practical interest, there are several barriers to performing such estimation, This includes a numerical approximation of a…

Methodology · Statistics 2025-02-07 Neil K. Chada , Ajay Jasra , Mohamed Maama , Raul Tempone

Inverse problems, i.e., estimating parameters of physical models from experimental data, are ubiquitous in science and engineering. The Bayesian formulation is the gold standard because it alleviates ill-posedness issues and quantifies…

Machine Learning · Statistics 2024-05-28 Sharmila Karumuri , Ilias Bilionis

We present a Bayesian approach to identify optimal transformations that map model input points to low dimensional latent variables. The "projection" mapping consists of an orthonormal matrix that is considered a priori unknown and needs to…

Machine Learning · Statistics 2021-09-22 Panagiotis Tsilifis , Piyush Pandita , Sayan Ghosh , Valeria Andreoli , Thomas Vandeputte , Liping Wang

The goal of this thesis is twofold; introduce the fundamentals of Bayesian inference and computation focusing on astronomical and cosmological applications, and present recent advances in probabilistic computational methods developed by the…

Instrumentation and Methods for Astrophysics · Physics 2023-03-31 Minas Karamanis

We describe a Bayesian sampling model for linking and constraining orbit models from angular observations of "streaks" in optical telescope images. Our algorithm is particularly suited to situations where the observation times are small…

Space Physics · Physics 2015-06-03 Michael D. Schneider

We study the application of a Bayesian method to extract relevant information from data for the case of a signal consisting of two or more decaying particles and its background. The method takes advantage of the dependence that exists in…

High Energy Physics - Phenomenology · Physics 2023-06-06 Ezequiel Alvarez

Advanced geometrical nanometrology is critical for process control in semiconductor manufacturing, supporting applications in, e.g., photonic integrated circuits, nanoelectronics, and emerging quantum and optoelectronic technologies.…

Gauss's method of orbit determination (OD) and its variants are among the most popular initial state estimation techniques for astronomers and engineers alike. However, owing to its assumptions regarding the two-body problem, Gauss's method…

Applications · Statistics 2026-03-03 Ishan Paranjape , Tarun Hejmadi , Utkarsh Ranjan Mishra , Suman Chakravorty

We have developed a new, fast method of estimating the orbital properties of a binary or triple system using as few as two epochs of astrometric data. FOBOS (Few Observation Binary Orbit Solver) uses a flat prior brute force Monte Carlo…

Solar and Stellar Astrophysics · Physics 2022-05-04 Rebecca J. Houghton , Simon P. Goodwin

Ordinary differential equations (ODEs) are used to model dynamic systems appearing in engineering, physics, biomedical sciences and many other fields. These equations contain unknown parameters, say $\bm\theta$ of physical significance…

Statistics Theory · Mathematics 2014-11-05 Prithwish Bhaumik , Subhashis Ghosal

This article addresses the problem of efficient Bayesian inference in dynamic systems using particle methods and makes a number of contributions. First, we develop a correlated pseudo-marginal (CPM) approach for Bayesian inference in state…

Methodology · Statistics 2016-12-22 P. Choppala , D. Gunawan , J. Chen , M. -N. Tran , R. Kohn

In this paper, we present a Bayesian channel estimation algorithm for multicarrier receivers based on pilot symbol observations. The inherent sparse nature of wireless multipath channels is exploited by modeling the prior distribution of…

Machine Learning · Statistics 2013-03-07 Niels Lovmand Pedersen , Carles Navarro Manchón Bernard Henri Fleury

Exoplanet research is carried out at the limits of the capabilities of current telescopes and instruments. The studied signals are weak, and often embedded in complex systematics from instrumental, telluric, and astrophysical sources.…

Instrumentation and Methods for Astrophysics · Physics 2019-02-06 Hannu Parviainen

Bayesian inference provides a principled way of estimating the parameters of a stochastic process that is observed discretely in time. The overdamped Brownian motion of a particle confined in an optical trap is generally modelled by the…

Data Analysis, Statistics and Probability · Physics 2017-02-01 Sudipta Bera , Shuvojit Paul , Rajesh Singh , Dipanjan Ghosh , Avijit Kundu , Ayan Banerjee , R. Adhikari

We describe regularized methods for image reconstruction and focus on the question of hyperparameter and instrument parameter estimation, i.e. unsupervised and myopic problems. We developed a Bayesian framework that is based on the \post…

Instrumentation and Methods for Astrophysics · Physics 2012-11-16 F. Orieux , J. -F. Giovannelli , T. Rodet , A. Abergel

In this paper, we address the fundamental problem of line spectral estimation in a Bayesian framework. We target model order and parameter estimation via variational inference in a probabilistic model in which the frequencies are…

Information Theory · Computer Science 2017-04-05 Mihai-Alin Badiu , Thomas Lundgaard Hansen , Bernard Henri Fleury

We propose a new Bayesian tracking and parameter learning algorithm for non-linear non-Gaussian multiple target tracking (MTT) models. We design a Markov chain Monte Carlo (MCMC) algorithm to sample from the posterior distribution of the…

Applications · Statistics 2015-10-28 Lan Jiang , Sumeetpal S. Singh , Sinan Yıldırım