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Light-field imaging is an emerging paradigm in biomedical optics, offering the unique ability to capture volumetric information in a single snapshot by encoding both the spatial and angular components of light. Unlike conventional…

Optics · Physics 2025-09-30 Ruixuan Zhao , Xuanwen Hua , Woongjae Baek , Zhaoqiang Wang , Shu Jia , Liang Gao

Phase imaging techniques extract the optical path-length information of a scene, whereas wavefront sensors provide the shape of an optical wavefront. Since these two applications have different technical requirements, they have developed…

Optics · Physics 2018-02-28 F. Soldevila , V. Durán , P. Clemente , J. Lancis , E. Tajahuerce

Photography usually requires optics in conjunction with a recording device (an image sensor). Eliminating the optics could lead to new form factors for cameras. Here, we report a simple demonstration of imaging using a bare CMOS sensor that…

Computer Vision and Pattern Recognition · Computer Science 2018-05-23 Ganghun Kim , Kyle Isaacson , Racheal Palmer , Rajesh Menon

Interfacing electrons and light enables ultrafast electron microscopy, quantum control of electrons, as well as new optical elements for high sensitivity imaging. Here we demonstrate for the first time programmable transverse electron beam…

We present a novel approach for imaging through scattering media that combines the principles of Fourier spatial filtering and single-pixel imaging. We compare the performance of our single-pixel imaging setup with that of a conventional…

Single particle cryo-electron microscopy is a vital tool for 3D characterization of protein structures. A typical workflow involves acquiring projection images of a collection of randomly oriented particles, picking and classifying…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 S. V. Venkatakrishnan , Puneet Juneja , Hugh O'Neill

In nuclear arms control and disarmament processes, it is crucial to determine whether an object is a nuclear weapon or not without revealing sensitive information about it. At the MIT: Laboratory for Nuclear Security and Policy, such a…

Numerical Analysis · Mathematics 2026-03-20 Christopher Fichtlscherer , R. Scott Kemp , Christina Brandt

Optical mixing experiments show the ability of amplifying a weak optical signal by superposing it with a stronger one. This principle has been demonstrated also for weak signals at the quantum level, down to a single photon. In the present…

Quantum Physics · Physics 2018-06-01 Shlomo Ruschin

Single-pixel imaging (SPI) has offered an unprecedented technique for capturing a targeted scenes without requiring either raster-scanned systems or muti-pixel detectors. However, in the current research, there are rare study reports about…

Single-pixel imaging (SPI) is a novel optical imaging technique by replacing the pixelated sensor array in a conventional camera with a single-pixel detector. In previous works, SPI is usually used for capturing object images or performing…

Computer Vision and Pattern Recognition · Computer Science 2022-10-13 Wei Huang , Jiaxiang Li , Shuming Jiao , Zibang Zhang

Single molecule localization microscopy (SMLM) techniques enable imaging biological samples well beyond the diffraction limit of light, but they vary significantly in their spatial and temporal resolutions. High-order statistical analysis…

Biological Physics · Physics 2016-03-15 Shachar Schidorsky , Xiyu Yi , Yair Razvag , Yonatan Golan , Shimon Weiss , Eilon Sherman

Sensitive mid-infrared (MIR) spectroscopy plays an indispensable role in various photon-starved conditions. However, the detection sensitivity of conventional MIR spectrometers is severely limited by excessive noises of the involved…

FRET-based approaches are a unique tool for sensing the immediate surroundings and interactions of (bio)molecules. FRET imaging and FLIM (Fluorescence Lifetime Imaging Microscopy) enable the visualization of the spatial distribution of…

Video reconstruction from a single motion-blurred image is a challenging problem, which can enhance the capabilities of existing cameras. Recently, several works addressed this task using conventional imaging and deep learning. Yet, such…

Image and Video Processing · Electrical Eng. & Systems 2022-12-20 Erez Yosef , Shay Elmalem , Raja Giryes

We propose a technique capable of imaging a distinct physical object with sub-Rayleigh resolution in an ordinary far-field imaging setup using single-photon sources and linear optical tools only. We exemplify our method for the case of a…

Quantum Physics · Physics 2009-11-24 C. Thiel , T. Bastin , J. von Zanthier , G. S. Agarwal

Macromolecules change their shape (conformation) in the process of carrying out their functions. The imaging by cryo-electron microscopy of rapidly-frozen, individual copies of macromolecules (single particles) is a powerful and general…

Biomolecules · Quantitative Biology 2022-11-22 Bogdan Toader , Fred J. Sigworth , Roy R. Lederman

A lensless digital holography enables wide-field microscopic imaging without the limitations imposed by optical lens performance. However, conventional holographic imaging often relies on magnifying optical systems to compensate for the low…

Optics · Physics 2025-06-24 Byung Gyu Chae

We have developed a single-shot imaging technique that can capture ultrafast events occurring on femtosecond to picosecond time scales. The technique is based on an optical pump-probe method, in which multiple time-delayed femtosecond…

Instrumentation and Detectors · Physics 2018-11-14 Sarang Yeola , Donghoon Kuk , Ki-Yong Kim

We propose a method of complex-amplitude Fourier single-pixel imaging (CFSI) with coherent structured illumination to acquire both the amplitude and phase of an object. In the proposed method, an object is illustrated by a series of…

We introduce a compressive single-pixel imaging (SPI) framework for high-resolution image capture in fractions of a second. This framework combines a dedicated sampling strategy with a tailored reconstruction method to enable high-quality…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Anna Pastuszczak , Rafał Stojek , Piotr Wróbel , Magdalena Cwojdzińska , Kacper Sobczak , Rafał Kotyński
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