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Multi-modal magnetic resonance (MR) imaging provides great potential for diagnosing and analyzing brain gliomas. In clinical scenarios, common MR sequences such as T1, T2 and FLAIR can be obtained simultaneously in a single scanning…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Ziqi Huang , Li Lin , Pujin Cheng , Linkai Peng , Xiaoying Tang

Introduction: Quantification of dynamic contrast-enhanced (DCE)-MRI has the potential to provide valuable clinical information, but robust pharmacokinetic modeling remains a challenge for clinical adoption. Methods: A 7-layer neural network…

Medical Physics · Physics 2024-05-22 Ouri Cohen , Soudabeh Kargar , Sungmin Woo , Alberto Vargas , Ricardo Otazo

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer diagnosis due to its ability to characterize tissue through contrast agent kinetics. However, traditional DCE-MRI protocols require multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Ruben D. Fonnegra , Maria Liliana Hernández , Juan C. Caicedo , Gloria M. Díaz

Objective: Gadolinium-based contrast agents (GBCAs) are commonly used in MRI scans of patients with gliomas to enhance brain tumor characterization using T1-weighted (T1W) MRI. However, there is growing concern about GBCA toxicity. This…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Zach Eidex , Mojtaba Safari , Richard L. J. Qiu , David S. Yu , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang

Accurate synthesis of a full 3D MR image containing tumours from available MRI (e.g. to replace an image that is currently unavailable or corrupted) would provide a clinician as well as downstream inference methods with important…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Raghav Mehta , Tal Arbel

\textit{Objective:} Gadolinium-based contrast agents (GBCAs) have been widely used to better visualize disease in brain magnetic resonance imaging (MRI). However, gadolinium deposition within the brain and body has raised safety concerns…

Image and Video Processing · Electrical Eng. & Systems 2022-07-19 Chao Chen , Catalina Raymond , Bill Speier , Xinyu Jin , Timothy F. Cloughesy , Dieter Enzmann , Benjamin M. Ellingson , Corey W. Arnold

Contrast-enhanced (CE) T1-weighted MRI is central to neuro-oncologic diagnosis but requires gadolinium-based agents, which add cost and scan time, raise environmental concerns, and may pose risks to patients. In this work, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Bastian Brandstötter , Erich Kobler

Despite its benefits for tumour detection and treatment, the administration of contrast agents in dynamic contrast-enhanced MRI (DCE-MRI) is associated with a range of issues, including their invasiveness, bioaccumulation, and a risk of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-03 Richard Osuala , Smriti Joshi , Apostolia Tsirikoglou , Lidia Garrucho , Walter H. L. Pinaya , Oliver Diaz , Karim Lekadir

Complete and high-quality multi-modal Magnetic Resonance Imaging (MRI) is essential for accurate neuro-oncological assessment, as each contrast provides complementary anatomical and pathological information. However, acquiring all…

Image and Video Processing · Electrical Eng. & Systems 2026-05-04 Zaid A. Abod , Furqan Aziz

F3-Net is a foundation model designed to overcome persistent challenges in clinical medical image segmentation, including reliance on complete multimodal inputs, limited generalizability, and narrow task specificity. Through flexible…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Seyedeh Sahar Taheri Otaghsara , Reza Rahmanzadeh

Every year thousands of patients are diagnosed with a glioma, a type of malignant brain tumor. Physicians use MR images as a key tool in the diagnosis and treatment of these patients. Neural networks show great potential to aid physicians…

Image and Video Processing · Electrical Eng. & Systems 2019-10-03 Eric Carver , Zhenzhen Dai , Evan Liang , James Snyder , Ning Wen

Accurate segmentation of brain tumors in MRI scans is critical for clinical diagnosis and treatment planning. We propose a semi-supervised, two-stage framework that extends the ReCoSeg approach to the larger and more heterogeneous BraTS…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Sara Yavari , Rahul Nitin Pandya , Jacob Furst

Dynamic contrast-enhanced (DCE) MRI is essential for breast cancer diagnosis and treatment. However, its reliance on contrast agents introduces safety concerns, contraindications, increased cost, and workflow complexity. To this end, we…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Sebastian Ibarra , Javier del Riego , Alessandro Catanese , Julian Cuba , Julian Cardona , Nataly Leon , Jonathan Infante , Karim Lekadir , Oliver Diaz , Richard Osuala

Glioma, the prevalent primary brain tumor, exhibits diverse aggressiveness levels and prognoses. Precise classification of glioma is paramount for treatment planning and predicting prognosis. This study aims to develop an algorithm to fuse…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Kiranmayee Janardhan , Christy Bobby Thomas

The magnetic resonance (MR) analysis of brain tumors is widely used for diagnosis and examination of tumor subregions. The overlapping area among the intensity distribution of healthy, enhancing, non-enhancing, and edema regions makes the…

Image and Video Processing · Electrical Eng. & Systems 2020-06-01 Mohammad Hamghalam , Baiying Lei , Tianfu Wang

Purpose: Ultra-high-field 7T MRI offers improved resolution and contrast over standard clinical field strengths (1.5T, 3T). However, 7T scanners are costly, scarce, and introduce additional challenges such as susceptibility artifacts. We…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Zach Eidex , Mojtaba Safari , Tonghe Wang , Vanessa Wildman , David S. Yu , Hui Mao , Erik Middlebrooks , Aparna Kesarwala , Xiaofeng Yang

Breast cancer is the most diagnosed cancer in women, with HER2 status critically guiding treatment decisions. Noninvasive prediction of HER2 status from dynamic contrast-enhanced MRI (DCE-MRI) could streamline diagnostics and reduce…

Quantitative Methods · Quantitative Biology 2025-10-17 Naomi Fridman , Anat Goldstein

Adversarially trained deep neural networks have significantly improved performance of single image super resolution, by hallucinating photorealistic local textures, thereby greatly reducing the perception difference between a real high…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Francis Tom , Himanshu Sharma , Dheeraj Mundhra , Tathagato Rai Dastidar , Debdoot Sheet

Digital Breast Tomosynthesis (DBT) is a widely used medical imaging modality for breast cancer screening and diagnosis, offering higher spatial resolution and greater detail through its 3D-like breast volume imaging capability. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-21 Yuexi Du , Regina J. Hooley , John Lewin , Nicha C. Dvornek

Dynamic Contrast Enhanced-Magnetic Resonance Imaging (DCE-MRI) is widely used to complement ultrasound examinations and x-ray mammography during the early detection and diagnosis of breast cancer. However, images generated by various MRI…

Image and Video Processing · Electrical Eng. & Systems 2021-06-18 Gourav Modanwal , Adithya Vellal , Maciej A. Mazurowski
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