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The application of ionizing radiation for diagnostic imaging is common around the globe. However, the process of imaging, itself, remains to be a relatively hazardous operation. Therefore, it is preferable to use as low a dose of ionizing…

Image and Video Processing · Electrical Eng. & Systems 2023-11-01 A. Demir , M. M. A. Shames , O. N. Gerek , S. Ergin , M. Fidan , M. Koc , M. B. Gulmezoglu , A. Barkana , C. Calisir

A major challenge in X-ray computed tomography (CT) is reducing radiation dose while maintaining high quality of reconstructed images. To reduce the radiation dose, one can reduce the number of projection views (sparse-view CT); however, it…

Machine Learning · Statistics 2019-09-17 Xuehang Zheng , Il Yong Chun , Zhipeng Li , Yong Long , Jeffrey A. Fessler

Fluorescence microscopy is a key driver to promote discoveries of biomedical research. However, with the limitation of microscope hardware and characteristics of the observed samples, the fluorescence microscopy images are susceptible to…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Xuanyu Tian , Qing Wu , Hongjiang Wei , Yuyao Zhang

Low-dose CT (LDCT) images are often accompanied by significant noise, which negatively impacts image quality and subsequent diagnostic accuracy. To address the challenges of multi-scale feature fusion and diverse noise distribution patterns…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Zhiting Zheng , Shuqi Wu , Wen Ding

Purpose: This work proposes a novel self-supervised noise-adaptive image denoising framework, called Repetition to Repetition (Rep2Rep) learning, for low-field (<1T) MRI applications. Methods: Rep2Rep learning extends the Noise2Noise…

Image and Video Processing · Electrical Eng. & Systems 2025-12-03 Nikola Janjušević , Jingjia Chen , Luke Ginocchio , Mary Bruno , Yuhui Huang , Yao Wang , Hersh Chandarana , Li Feng

Low Dose Computed Tomography (LDCT) is widely used as an imaging solution to aid diagnosis and other clinical tasks. However, this comes at the price of a deterioration in image quality due to the low dose of radiation used to reduce the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Taifour Yousra Nabila , Azeddine Beghdadi , Marie Luong , Zuheng Ming , Habib Zaidi , Faouzi Alaya Cheikh

Purpose: This study aims to improve 0.55T T2-weighted PROPELLER lung MRI through a self-supervised joint reconstruction and denoising model. Methods: T2-weighted 0.55T lung MRI dataset including 44 patients with previous covid infection…

Image and Video Processing · Electrical Eng. & Systems 2025-12-03 Jingjia Chen , Haoyang Pei , Christoph Maier , Mary Bruno , Qiuting Wen , Seon-Hi Shin , William Moore , Hersh Chandarana , Li Feng

This paper presents a dictionary learning-based method with region-specific image patches to maximize the utility of the powerful sparse data processing technique for CT image reconstruction. Considering heterogeneous distributions of image…

Medical Physics · Physics 2020-10-26 Qiong Xu , Jeff Wang , Hiroki Shirato , Lei Xing

Low-dose CT denoising is a challenging task that has been studied by many researchers. Some studies have used deep neural networks to improve the quality of low-dose CT images and achieved fruitful results. In this paper, we propose a deep…

Image and Video Processing · Electrical Eng. & Systems 2019-02-28 Maryam Gholizadeh-Ansari , Javad Alirezaie , Paul Babyn

Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Wenjun Xia , Yongyi Shi , Chuang Niu , Wenxiang Cong , Ge Wang

The use of deep learning has successfully solved several problems in the field of medical imaging. Deep learning has been applied to the CT denoising problem successfully. However, the use of deep learning requires large amounts of data to…

Image and Video Processing · Electrical Eng. & Systems 2022-04-04 Mayank Patwari , Ralf Gutjahr , Rainer Raupach , Andreas Maier

Low-dose computed tomography (CT) plays a significant role in reducing the radiation risk in clinical applications. However, lowering the radiation dose will significantly degrade the image quality. With the rapid development and wide…

Image and Video Processing · Electrical Eng. & Systems 2022-12-08 Bin Huang , Liu Zhang , Shiyu Lu , Boyu Lin , Weiwen Wu , Qiegen Liu

Assume you encounter an inverse problem that shall be solved for a large number of data, but no ground-truth data is available. To emulate this encounter, in this study, we assume it is unknown how to solve the imaging problem of Computed…

The recently proposed sparsifying transform models incur low computational cost and have been applied to medical imaging. Meanwhile, deep models with nested network structure reveal great potential for learning features in different layers.…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Xikai Yang , Zhishen Huang , Yong Long , Saiprasad Ravishankar

Low-dose computed tomography (LDCT) denoising is an important problem in CT research. Compared to the normal dose CT (NDCT), LDCT images are subjected to severe noise and artifacts. Recently in many studies, vision transformers have shown…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Dayang Wang , Fenglei Fan , Zhan Wu , Rui Liu , Fei Wang , Hengyong Yu

Low-dose CT has been a key diagnostic imaging modality to reduce the potential risk of radiation overdose to patient health. Despite recent advances, CNN-based approaches typically apply filters in a spatially invariant way and adopt…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Lu Xu , Yuwei Zhang , Ying Liu , Daoye Wang , Mu Zhou , Jimmy Ren , Jingwei Wei , Zhaoxiang Ye

Real-world low-light images captured by imaging devices suffer from poor visibility and require a domain-specific enhancement to produce artifact-free outputs that reveal details. In this paper, we propose an unpaired low-light image…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Aupendu Kar , Sobhan K. Dhara , Debashis Sen , Prabir K. Biswas

Deep learning has demonstrated strong potential for MRI reconstruction. However, conventional supervised learning requires high-quality, high-SNR references for network training, which are often difficult or impossible to obtain in…

Image and Video Processing · Electrical Eng. & Systems 2026-01-01 Haoyang Pei , Nikola Janjuvsevic , Renqing Luo , Ding Xia , Xiang Xu , William Moore , Yao Wang , Hersh Chandarana , Li Feng

Low-dose computed tomography (CT) has attracted a major attention in the medical imaging field, since CT-associated x-ray radiation carries health risks for patients. The reduction of CT radiation dose, however, compromises the…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Hongming Shan , Yi Zhang , Qingsong Yang , Uwe Kruger , Mannudeep K. Kalra , Ling Sun , Wenxiang Cong , Ge Wang

Helical CT has been widely used in clinical diagnosis. Sparsely spaced multidetector in z direction can increase the coverage of the detector provided limited detector rows. It can speed up volumetric CT scan, lower the radiation dose and…

Medical Physics · Physics 2019-10-24 Ao Zheng , Hewei Gao , Li Zhang , Yuxiang Xing