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In ophthalmology, the study of the retinal microcirculation is a key issue in the analysis of many ocular and systemic diseases, like hypertension or diabetes. This motivates the research on improving the retinal vasculature segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 José Morano , Álvaro S. Hervella , Noelia Barreira , Jorge Novo , José Rouco

Microvascular anatomy is known to be involved in various neurological disorders. However, understanding these disorders is hindered by the lack of imaging modalities capable of capturing the comprehensive three-dimensional vascular network…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Etienne Chollet , Yaël Balbastre , Chiara Mauri , Caroline Magnain , Bruce Fischl , Hui Wang

The accurate segmentation of retinal vessels in fundus images is a great challenge in medical image segmentation tasks due to their highly complex structure from other organs.Currently, deep-learning based methods for retinal cessel…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Yiwang Dong , Xiangyu Deng

Retinal vessel segmentation is critical for the early diagnosis of vision-threatening and systemic diseases, especially in real-world clinical settings with limited computational resources. Although significant improvements have been made…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Mehwish Mehmood , Shahzaib Iqbal , Tariq Mahmood Khan , Ivor Spence , Muhammad Fahim

Precise segmentation of retinal arteries and veins carries the diagnosis of systemic cardiovascular conditions. However, standard convolutional architectures often yield topologically disjointed segmentations, characterized by gaps and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Iftekhar Ahmed , Shakib Absar , Aftar Ahmad Sami , Shadman Sakib , Debojyoti Biswas , Seraj Al Mahmud Mostafa

Due to the lack of automated methods, to diagnose cerebrovascular disease, time-of-flight magnetic resonance angiography (TOF-MRA) is assessed visually, making it time-consuming. The commonly used encoder-decoder architectures for…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Syed Farhan Abbas , Nguyen Thanh Duc , Yoonguu Song , Kyungwon Kim , Ekta Srivastava , Boreom Lee

The measurement of retinal blood flow (RBF) in capillaries can provide a powerful biomarker for the early diagnosis and treatment of ocular diseases. However, no single modality can determine capillary flowrates with high precision.…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Chiao-Yi Wang , Faranguisse Kakhi Sadrieh , Yi-Ting Shen , Shih-En Chen , Sarah Kim , Victoria Chen , Achyut Raghavendra , Dongyi Wang , Osamah Saeedi , Yang Tao

We propose a generalized focal loss function based on the Tversky index to address the issue of data imbalance in medical image segmentation. Compared to the commonly used Dice loss, our loss function achieves a better trade off between…

Computer Vision and Pattern Recognition · Computer Science 2018-10-19 Nabila Abraham , Naimul Mefraz Khan

The detection of retinal vessel is of great importance in the diagnosis and treatment of many ocular diseases. Many methods have been proposed for vessel detection. However, most of the algorithms neglect the connectivity of the vessels,…

Image and Video Processing · Electrical Eng. & Systems 2019-10-29 Lei Mou , Li Chen , Jun Cheng , Zaiwang Gu , Yitian Zhao , Jiang Liu

Abnormalities in retinal fundus images may indicate certain pathologies such as diabetic retinopathy, hypertension, stroke, glaucoma, retinal macular edema, venous occlusion, and atherosclerosis, making the study and analysis of retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Yuzhuo Chen , Zetong Chen , Yuanyuan Liu

Automated medical image segmentation is an essential task to aid/speed up diagnosis and treatment procedures in clinical practices. Deep convolutional neural networks have exhibited promising performance in accurate and automatic seminal…

Medical Physics · Physics 2022-03-08 Reza Karimzadeh , Emad Fatemizadeh , Hossein Arabi

Vessel segmentation is widely used to help with vascular disease diagnosis. Vessels reconstructed using existing methods are often not sufficiently accurate to meet clinical use standards. This is because 3D vessel structures are highly…

Image and Video Processing · Electrical Eng. & Systems 2023-01-09 Gangming Zhao , Kongming Liang , Chengwei Pan , Fandong Zhang , Xianpeng Wu , Xinyang Hu , Yizhou Yu

Automated vascular segmentation on optical coherence tomography angiography (OCTA) is important for the quantitative analyses of retinal microvasculature in neuroretinal and systemic diseases. Despite recent improvements, artifacts continue…

Image and Video Processing · Electrical Eng. & Systems 2021-04-22 Yih-Cherng Lee , Ling Yeung

Retinal imaging has emerged as a promising method of addressing this challenge, taking advantage of the unique structure of the retina. The retina is an embryonic extension of the central nervous system, providing a direct in vivo window…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Syed Javed , Tariq M. Khan , Abdul Qayyum , Arcot Sowmya , Imran Razzak

Cerebrovascular pathology significantly contributes to cognitive decline and neurological disorders, underscoring the need for advanced tools to assess vascular integrity. Three-dimensional Time-of-Flight Magnetic Resonance Angiography (3D…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Abrar Faiyaz , Nhat Hoang , Giovanni Schifitto , Md Nasir Uddin

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging modality for the visualisation of microvasculature in vivo that has encountered broad adoption in retinal research. OCTA potential in the assessment of…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Ylenia Giarratano , Eleonora Bianchi , Calum Gray , Andrew Morris , Tom MacGillivray , Baljean Dhillon , Miguel O. Bernabeu

Background and Objective: Infra-red scanning laser ophthalmoscope (IRSLO) images are akin to colour fundus photographs in displaying the posterior pole and retinal vasculature fine detail. While there are many trained networks readily…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Adam Threlfall , Samuel Gibbon , James Cameron , Tom MacGillivray

Retinal vessel segmentation serves as a critical prerequisite for automated diagnosis of retinal pathologies. While recent advances in Convolutional Neural Networks (CNNs) have demonstrated promising performance in this task, significant…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Zhanqiang Guo , Jianjiang Feng , Jie Zhou

Color fundus photography (CFP) is central to diagnosing and monitoring retinal disease, yet its acquisition variability (e.g., illumination changes) often degrades image quality, which motivates robust enhancement methods. Unpaired…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Xuanzhao Dong , Wenhui Zhu , Yujian Xiong , Xiwen Chen , Hao Wang , Xin Li , Jiajun Cheng , Zhipeng Wang , Shao Tang , Oana Dumitrascu , Yalin Wang

The morphology of blood vessels in retinal fundus images is an important indicator of diseases like glaucoma, hypertension and diabetic retinopathy. The accuracy of retinal blood vessels segmentation affects the quality of retinal image…

Computer Vision and Pattern Recognition · Computer Science 2018-03-02 A. M. R. R. Bandara , P. W. G. R. M. P. B. Giragama