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Feature importance methods using unrestricted permutations are flawed due to extrapolation errors; such errors appear in all non-trivial variable importance approaches. We propose three new approaches: conditional model reliance and…

Machine Learning · Statistics 2026-04-14 Emanuele Borgonovo , Francesco Cappelli , Xuefei Lu , Elmar Plischke , Cynthia Rudin

Machine learning (ML) models are powerful tools for detecting complex patterns within data, yet their "black box" nature limits their interpretability, hindering their use in critical domains like healthcare and finance. To address this…

Machine Learning · Computer Science 2025-02-17 Winston Chen , Yifan Jiang , William Stafford Noble , Yang Young Lu

A classification technique incorporating a novel feature derivation method is proposed for predicting failure of a system or device with multivariate time series sensor data. We treat the multivariate time series sensor data as images for…

Machine Learning · Computer Science 2021-09-22 Lanfa Frank Wang , Danjue Li

In large scale multiple testing problems, a two-class empirical Bayes approach can be used to control the false discovery rate (Fdr) for the entire array of hypotheses under study. A sample splitting step is incorporated to modify that…

Computation · Statistics 2019-12-13 Paramita Chakraborty , Chong Ma , John Grego , James Lynch

Consider the problem of testing $s$ hypotheses simultaneously. The usual approach restricts attention to procedures that control the probability of even one false rejection, the familywise error rate (FWER). If $s$ is large, one might be…

Statistics Theory · Mathematics 2007-11-06 Joseph P. Romano , Michael Wolf

We propose the Terminating-Random Experiments (T-Rex) selector, a fast variable selection method for high-dimensional data. The T-Rex selector controls a user-defined target false discovery rate (FDR) while maximizing the number of selected…

Methodology · Statistics 2024-03-14 Jasin Machkour , Michael Muma , Daniel P. Palomar

Efforts to develop more efficient multiple hypothesis testing procedures for false discovery rate (FDR) control have focused on incorporating an estimate of the proportion of true null hypotheses (such procedures are called adaptive) or…

Methodology · Statistics 2017-02-13 Joshua D. Habiger

While traditional multiple testing procedures prohibit adaptive analysis choices made by users, Goeman and Solari (2011) proposed a simultaneous inference framework that allows users such flexibility while preserving high-probability bounds…

Statistics Theory · Mathematics 2021-01-05 Eugene Katsevich , Aaditya Ramdas

Due to the vast testing space, the increasing demand for effective and efficient testing of deep neural networks (DNNs) has led to the development of various DNN test case prioritization techniques. However, the fact that DNNs can deliver…

Software Engineering · Computer Science 2024-09-17 Jialuo Chen , Jingyi Wang , Xiyue Zhang , Youcheng Sun , Marta Kwiatkowska , Jiming Chen , Peng Cheng

We propose the conditional predictive impact (CPI), a consistent and unbiased estimator of the association between one or several features and a given outcome, conditional on a reduced feature set. Building on the knockoff framework of…

Methodology · Statistics 2021-05-14 David S. Watson , Marvin N. Wright

Quantifying how genomic features influence different parts of an outcome distribution requires statistical tools that go beyond mean regression, especially in ultrahigh-dimensional settings. Motivated by the study of LINE-1 activity in…

Methodology · Statistics 2025-11-27 Sang Kyu Lee , Tongwu Zhang , Hyokyoung G. Hong , Haolei Weng

This paper studies model selection consistency for high dimensional sparse regression when data exhibits both cross-sectional and serial dependency. Most commonly-used model selection methods fail to consistently recover the true model when…

Methodology · Statistics 2018-09-12 Jianqing Fan , Yuan Ke , Kaizheng Wang

We propose a feature screening method that integrates both feature-feature and feature-target relationships. Inactive features are identified via a penalized minimum Redundancy Maximum Relevance (mRMR) procedure, which is the continuous…

Machine Learning · Statistics 2025-08-27 Peter Naylor , Benjamin Poignard , Héctor Climente-González , Makoto Yamada

For a high-dimensional linear model with a finite number of covariates measured with error, we study statistical inference on the parameters associated with the error-prone covariates, and propose a new corrected decorrelated score test and…

Methodology · Statistics 2020-01-29 Mengyan Li , Runze Li , Yanyuan Ma

Distribution-free predictive inference beyond the construction of prediction sets has gained a lot of interest in recent applications. One such application is the selection task, where the objective is to design a reliable selection rule to…

Methodology · Statistics 2025-01-07 Yonghoon Lee , Zhimei Ren

In machine learning and pattern recognition, feature selection has been a hot topic in the literature. Unsupervised feature selection is challenging due to the loss of labels which would supply the related information.How to define an…

Machine Learning · Computer Science 2015-01-14 Chang Liu , Yi Xu

This paper provides two general classes of multiple decision functions where each member of the first class strongly controls the family-wise error rate (FWER), while each member of the second class strongly controls the false discovery…

Statistics Theory · Mathematics 2019-11-19 Edsel A. Pena , Joshua D. Habiger , Wensong Wu

We consider the problem of identifying whether findings replicate from one study of high dimension to another, when the primary study guides the selection of hypotheses to be examined in the follow-up study as well as when there is no…

Methodology · Statistics 2014-01-28 Marina Bogomolov , Ruth Heller

Some effort has been undertaken over the last decade to provide conditions for the control of the false discovery rate by the linear step-up procedure (LSU) for testing $n$ hypotheses when test statistics are dependent. In this paper we…

Statistics Theory · Mathematics 2007-10-18 Helmut Finner , Thorsten Dickhaus , Markus Roters

In many applications, the process of identifying a specific feature of interest often involves testing multiple hypotheses for their joint statistical significance. Examples include mediation analysis which simultaneously examines the…

Methodology · Statistics 2023-05-30 Linsui Deng , Kejun He , Xianyang Zhang
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