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Several important aspects related to SARS-CoV-2 transmission are not well known due to a lack of appropriate data. However, mathematical and computational tools can be used to extract part of this information from the available data, like…

Populations and Evolution · Quantitative Biology 2022-04-01 Nicolas Franco , Pietro Coletti , Lander Willem , Leonardo Angeli , Adrien Lajot , Steven Abrams , Philippe Beutels , Christel Faes , Niel Hens

Understanding the viral dynamics and immunizing antibodies of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial for devising better therapeutic and prevention strategies for COVID-19. Here, we present a Bayesian…

Applications · Statistics 2023-07-27 Tracy Q. Dong , Elizabeth R. Brown

In times of outbreaks, an essential requirement for better monitoring is the evaluation of the number of undiagnosed infected individuals. An accurate estimate of this fraction is crucial for the assessment of the situation and the…

Populations and Evolution · Quantitative Biology 2021-03-17 Akiva B. Melka , Yoram Louzoun

Although previous infection and vaccination provide protection against SARS-CoV-2 infection, both reinfection and breakthrough infection are possible events whose occurrence would increase with time after first exposure to the antigen and…

Populations and Evolution · Quantitative Biology 2022-06-07 Ariel Félix Gualtieri , Carolina de la Cal , Augusto Francisco Toma , Pedro Hecht

In general, the rates of infection and removal (whether through recovery or death) are nonlinear functions of the number of infected and susceptible individuals. One of the simplest models for the spread of infectious diseases is the SIR…

Populations and Evolution · Quantitative Biology 2026-05-11 Seong Jun Park , M. Y. Choi

Superspreading complicates the study of SARS-CoV-2 transmission. I propose a model for aggregated case data that accounts for superspreading and improves statistical inference. In a Bayesian framework, the model is estimated on German data…

Applications · Statistics 2020-11-10 Patrick W. Schmidt

Although traditional models of epidemic spreading focus on the number of infected, susceptible and recovered individuals, a lot of attention has been devoted to integrate epidemic models with population genetics. Here we develop an…

Populations and Evolution · Quantitative Biology 2021-11-24 Vitor M. Marquioni , Marcus A. M. de Aguiar

Monitoring wastewater concentrations of SARS-CoV-2 yields a low-cost, noninvasive method for tracking disease prevalence and provides early warning signs of upcoming outbreaks in the serviced communities. There is tremendous clinical and…

A numerical framework for the 'real-time' estimation of the infection risk from airborne diseases (e.g., SARS-CoV-2) in indoor spaces such as hospitals, restaurants, cinemas or teaching rooms is proposed. The developed model is based on the…

Based on the SIRD-model a new model including time-delay is proposed for a description of the outbreak of the novel coronavirus Sars-CoV-2 pandemic. All data were analysed by representing all quantities as a function of the susceptible…

Populations and Evolution · Quantitative Biology 2024-08-16 Olivier Merlo

The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insights into the speed of disease spread and…

Methodology · Statistics 2020-07-06 Tianjian Zhou , Yuan Ji

The COVID-19 pandemic provides new motivation for a classic problem in epidemiology: estimating the empirical rate of transmission during an outbreak (formally, the time-varying reproduction number) from case counts. While standard methods…

Methodology · Statistics 2020-12-08 Bryan Wilder , Michael J. Mina , Milind Tambe

The question of how SARS-CoV-2 is transmitted remains surprisingly controversial today, especially with reference to airborne transmission. In fact, despite a large body of scientific evidence, health and regulatory authorities still…

Medical Physics · Physics 2021-10-07 G. Buonanno , A. Robotto , E. Brizio , L. Morawska , A. Civra , F. Corino , D. Lembo , G. Ficco , L. Stabile

Using recent data from voluntary mass testing, I provide credible bounds on prevalence of SARS-CoV-2 for Austrian counties in early December 2020. When estimating prevalence, a natural missing data problem arises: no test results are…

General Economics · Economics 2020-12-23 Gabriel Ziegler

The spread of COVID-19 has been greatly impacted by regulatory policies and behavior patterns that vary across counties, states, and countries. Population-level dynamics of COVID-19 can generally be described using a set of ordinary…

Applications · Statistics 2022-04-11 Joshua P. Keller , Tianjian Zhou , Andee Kaplan , G. Brooke Anderson , Wen Zhou

Branching process inspired models are widely used to estimate the effective reproduction number -- a useful summary statistic describing an infectious disease outbreak -- using counts of new cases. Case data is a real-time indicator of…

Methodology · Statistics 2023-10-03 Isaac H. Goldstein , Jon Wakefield , Volodymyr M. Minin

This technical report describes a dynamic causal model of the spread of coronavirus through a population. The model is based upon ensemble or population dynamics that generate outcomes, like new cases and deaths over time. The purpose of…

Following the emergence of a novel coronavirus (SARS-CoV-2) and its spread outside of China, Europe has experienced large epidemics. In response, many European countries have implemented unprecedented non-pharmaceutical interventions…

This work aims to assess the risks of Covid-19 disease spread in diverse daily-life situations (referred to as scenarios) involving crowds of maskless pedestrians, mostly outdoors. More concretely, we develop a method to infer the global…

Physics and Society · Physics 2021-11-04 Willy Garcia , Simon Mendez , Baptiste Fray , Alexandre Nicolas

We consider the SEIRS epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. The control of the pandemic dynamics is…

Populations and Evolution · Quantitative Biology 2026-03-31 J. Ilnytskyi , T. Patsahan