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This study creates a physiologically realistic virtual patient database (VPD), representing the human arterial system, for the primary purpose of studying the affects of arterial disease on haemodynamics. A low dimensional representation of…

Medical Physics · Physics 2021-08-05 Gareth Jones , Jim Parr , Perumal Nithiarasu , Sanjay Pant

Monte Carlo (MC) algorithms are commonly employed to explore high-dimensional parameter spaces constrained by data. All the statistical information obtained in the output of these analyses is contained in the Markov chains, which one needs…

Cosmology and Nongalactic Astrophysics · Physics 2022-09-21 Adrià Gómez-Valent

Myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT) is a widely used and cost-effective diagnostic tool for coronary artery disease. However, the lengthy scanning time in this imaging procedure can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Zezhang Yang , Zitong Yu , Nuri Choi , Abhinav K. Jha

A method for the multifidelity Monte Carlo (MFMC) estimation of statistical quantities is proposed which is applicable to computational budgets of any size. Based on a sequence of optimization problems each with a globally minimizing…

Numerical Analysis · Mathematics 2022-11-15 Anthony Gruber , Max Gunzburger , Lili Ju , Zhu Wang

Ultracold neutrons (UCN) with kinetic energies up to 300 neV can be stored in material or magnetic confinements for hundreds of seconds. This makes them a very useful tool for probing fundamental symmetries of nature, by searching for…

Instrumentation and Detectors · Physics 2018-12-26 N. J. Ayres , E. Chanel , B. Clement , P. G. Harris , R. Picker , G. Pignol , W. Schreyer , G. Zsigmond

Artificial Neural Networks were recently shown to be an efficient representation of highly-entangled many-body quantum states. In practical applications, neural-network states inherit numerical schemes used in Variational Monte Carlo, most…

Disordered Systems and Neural Networks · Physics 2020-01-22 Or Sharir , Yoav Levine , Noam Wies , Giuseppe Carleo , Amnon Shashua

Inverse optimization (IO) is used to estimate unknown parameters of an optimization model from observed decisions. In the data-driven context, the estimated parameters are inherently uncertain, yet quantifying this uncertainty has received…

Optimization and Control · Mathematics 2026-05-26 Timothy C. Y. Chan , Nathan Sandholtz , Nasrin Yousefi

Optimal decision-making under partial observability requires agents to balance reducing uncertainty (exploration) against pursuing immediate objectives (exploitation). In this paper, we introduce a novel policy optimization framework for…

Machine Learning · Computer Science 2025-12-05 Hany Abdulsamad , Sahel Iqbal , Simo Särkkä

This paper considers a new approach to using Markov chain Monte Carlo (MCMC) in contexts where one may adopt multilevel (ML) Monte Carlo. The underlying problem is to approximate expectations w.r.t. an underlying probability measure that is…

Numerical Analysis · Mathematics 2018-06-27 Ajay Jasra , Kody Law , Yaxian Xu

Assessing the practical identifiability of epidemic models is essential for determining whether parameters can be meaningfully estimated from observed data. Monte Carlo (MC) methods provide an accessible and intuitive framework; however,…

Methodology · Statistics 2025-10-01 Chiara Mattamira , Olivia Prosper Feldman

Decision making for dynamic systems is challenging due to the scale and dynamicity of such systems, and it is comprised of decisions at strategic, tactical, and operational levels. One of the most important aspects of decision making is…

Applications · Statistics 2019-11-12 Sara Masoud , Bijoy Chowdhury , Young-Jun Son , Russell Tronstad

Due to the escalating growth of big data sets in recent years, new Bayesian Markov chain Monte Carlo (MCMC) parallel computing methods have been developed. These methods partition large data sets by observations into subsets. However, for…

Methodology · Statistics 2019-01-21 Zheng Wei , Erin M. Conlon

Objective: To develop and validate an independent Monet Carlo dose calculation engine to support for software verification of treatment planning systems and quality assurance workflow. Method: GATE Monte Carlo toolkit was employed to…

Medical Physics · Physics 2021-07-27 A. Asadi , A. Akhavanallaf , S. A. Hosseini , N. vosoughi , H. Zaidi

We introduce a new Markov Chain Monte Carlo (MCMC) algorithm with parallel tempering for fitting theoretical models of horizon-scale images of black holes to the interferometric data from the Event Horizon Telescope (EHT). The algorithm…

Instrumentation and Methods for Astrophysics · Physics 2020-05-20 Dimitrios Psaltis , Feryal Ozel , Lia Medeiros , Pierre Christian , Junhan Kim , Chi-kwan Chan , Landen J. Conway , Carolyn A. Raithel , Dan Marrone , Tod R. Lauer

The Internet of Medical Things (IoMT) has dramatically benefited medical professionals that patients and physicians can access from all regions. Although the automatic detection and prediction of diseases such as melanoma and leukemia is…

Computer Vision and Pattern Recognition · Computer Science 2023-12-13 Alhassan Mabrouk , Abdelghani Dahou , Mohamed Abd Elaziz , Rebeca P. Díaz Redondo , Mohammed Kayed

Conventional breast cancer imaging techniques are nowadays based on the use of ionising radiations or ultrasound waves for the inspection of breast areas. Nevertheless, these conventional techniques present some drawbacks related to patient…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Michele Ambrosanio , Stefano Franceschini , Vito Pascazio , Fabio Baselice

Within the framework of a virtual clinical trial for breast imaging, we aim to develop numerical observers that follow the same detection performance trends as those of a typical human observer. In our prior work, we showed that by…

Computer Vision and Pattern Recognition · Computer Science 2014-08-07 Ali R. N. Avanaki , Kathryn S. Espig , Albert Xthona , Tom R. L. Kimpe , Predrag R. Bakic , Andrew D. A. Maidment

Markov Chain Monte Carlo (MCMC) methods for sampling probability density functions (combined with abundant computational resources) have transformed the sciences, especially in performing probabilistic inferences, or fitting models to data.…

Instrumentation and Methods for Astrophysics · Physics 2018-05-23 David W. Hogg , Daniel Foreman-Mackey

We consider the computation of the permanent of a binary n by n matrix. It is well- known that the exact computation is a #P complete problem. A variety of Markov chain Monte Carlo (MCMC) computational algorithms have been introduced in the…

Computation · Statistics 2013-05-30 Ajay Jasra , Junshan Wang

Since the middle of the 1940's scientists have used Monte Carlo (MC) simulations to obtain information about physical processes. This has proved a accurate and and reliable method to obtain this information. Through out resent years…

Astrophysics of Galaxies · Physics 2012-07-02 Thomas Amby Ottosen
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