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Background and Purpose: We aimed to develop and evaluate an automatic acute ischemic stroke-related (AIS) detection system involving a two-stage deep learning model. Methods: We included 238 cases from two different institutions.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Mizuho Nishio , Sho Koyasu , Shunjiro Noguchi , Takao Kiguchi , Kanako Nakatsu , Thai Akasaka , Hiroki Yamada , Kyo Itoh

Stroke is the second most frequent cause of death world wide with an annual mortality of around 5.5 million. Recurrence rates of stroke are between 5 and 25% in the first year. As mortality rates for relapses are extraordinarily high (40%)…

Quantitative, volumetric analysis of Magnetic Resonance Imaging (MRI) is a fundamental way researchers study the brain in a host of neurological conditions including normal maturation and aging. Despite the availability of open-source brain…

Quantitative Methods · Quantitative Biology 2019-11-15 Aakash Kaku , Chaitra V. Hegde , Jeffrey Huang , Sohae Chung , Xiuyuan Wang , Matthew Young , Alireza Radmanesh , Yvonne W. Lui , Narges Razavian

About 5-8% of individuals over the age of 60 have dementia. With our ever-aging population this number is likely to increase, making dementia one of the most important threats to public health in the 21st century. Given the phenotypic…

Image and Video Processing · Electrical Eng. & Systems 2021-02-16 Magnus Magnusson , Askell Love , Lotta M. Ellingsen

Automated noninvasive cardiac diagnosis plays a critical role in the early detection of cardiac disorders and cost-effective clinical management. Automated diagnosis involves the automated segmentation and analysis of cardiac images.…

Image and Video Processing · Electrical Eng. & Systems 2025-04-21 Racheal Mukisa , Arvind K. Bansal

Portable CT scanners enable early stroke detection in prehospital and low-resource settings but require reduced radiation doses, introducing noise that degrades diagnostic reliability. We present a deep learning framework for stroke…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Rhea Ghosal , Ronok Ghosal , Eileen Lou

Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system, characterized by the appearance of focal lesions in the white and gray matter that topographically correlate with an individual…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Yang Ma , Chaoyi Zhang , Mariano Cabezas , Yang Song , Zihao Tang , Dongnan Liu , Weidong Cai , Michael Barnett , Chenyu Wang

Artificial intelligence (AI) has seen a significant surge in popularity, particularly in its application to medicine. This study explores AI's role in diagnosing leukoencephalopathy, a small vessel disease of the brain, and a leading cause…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Z. Cernekova , V. Sisik , F. Jafari

Intracranial hemorrhage, bleeding that occurs inside the cranium, is a serious health problem requiring rapid and often intensive medical treatment. Such a condition is traditionally diagnosed by highly-trained specialists analyzing…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Utkarsh Chandra Srivastava , Anshuman Singh , K. Sree Kumar

Mechanical thrombectomy has become the standard of care in patients with stroke due to large vessel occlusion (LVO). However, only 50% of successfully treated patients show a favorable outcome. We developed and evaluated interpretable deep…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Lisa Herzog , Pascal Bühler , Ezequiel de la Rosa , Beate Sick , Susanne Wegener

BACKGROUND AND PURPOSE: Cerebral aneurysm is one of the most common cerebrovascular diseases, and SAH caused by its rupture has a very high mortality and disability rate. Existing automatic segmentation methods based on DLMs with TOF-MRA…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Meng Chen , Chen Geng , Dongdong Wang , Jiajun Zhang , Ruoyu Di , Fengmei Li , Zhiyong Zhou , Sirong Piao , Yuxin Li , Yaikang Dai

Stroke poses a significant global health threat, with millions affected annually, leading to substantial morbidity and mortality. Current stroke risk assessment for the general population relies on markers such as demographics, blood tests,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Yu Xi Huang , Simon Mahler , Aidin Abedi , Julian Michael Tyszka , Yu Tung Lo , Patrick D. Lyden , Jonathan Russin , Charles Liu , Changhuei Yang

Large vessel occlusion (LVO) plays an important role in the diagnosis of acute ischemic stroke. Identifying LVO of patients in the early stage on admission would significantly lower the probabilities of suffering from severe effects due to…

Image and Video Processing · Electrical Eng. & Systems 2019-06-20 Jia You , Philip L. H. Yu , Anderson C. O. Tsang , Eva L. H. Tsui , Pauline P. S. Woo , Gilberto K. K. Leung

The aorta is the body's largest arterial vessel, serving as the primary pathway for oxygenated blood within the systemic circulation. Aortic aneurysms consistently rank among the top twenty causes of mortality in the United States. Thoracic…

Image and Video Processing · Electrical Eng. & Systems 2025-09-17 Jiasong Chen , Linchen Qian , Ruonan Gong , Christina Sun , Tongran Qin , Thuy Pham , Caitlin Martin , Mohammad Zafar , John Elefteriades , Wei Sun , Liang Liang

Brain lesion volume measured on T2 weighted MRI images is a clinically important disease marker in multiple sclerosis (MS). Manual delineation of MS lesions is a time-consuming and highly operator-dependent task, which is influenced by…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Jinwei Zhang , Qihao Zhang , Jeremy Kim , Shun Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Mert R. Sabuncu , Yi Wang

Collateral circulation results from specialized anastomotic channels which are capable of providing oxygenated blood to regions with compromised blood flow caused by ischemic injuries. The quality of collateral circulation has been…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Giles Tetteh , Fernando Navarro , Johannes Paetzold , Jan Kirschke , Claus Zimmer , Bjoern H. Menze

Cerebrovascular diseases (CVD) can lead to stroke and dementia. Stroke is the second leading cause of death world wide and dementia incidence is increasing by the year. There are several markers of CVD that are visible on brain imaging,…

Coronary Artery Disease (CAD) results from plaque deposit in a coronary artery. Early diagnosis is imperative, so a non-invasive detection method is being developed to identify acoustic signals caused by partial occlusions in the artery.…

Signal Processing · Electrical Eng. & Systems 2024-04-25 Bansi Mandalia , Steve Greenwald , Simon Shaw , Gregory Slabaugh

Medical brain image analysis is a necessary step in Computer Assisted /Aided Diagnosis (CAD) systems. Advancements in both hardware and software in the past few years have led to improved segmentation and classification of various diseases.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-15 Darwin Castillo , Vasudevan Lakshminarayanan , Maria J. Rodriguez-Alvarez

Coronary artery calcium (CAC) is a significant marker of atherosclerosis and cardiovascular events. In this work we present a system for the automatic quantification of calcium score in ECG-triggered non-contrast enhanced cardiac computed…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 G. Santini , D. Della Latta , N. Martini , G. Valvano , A. Gori , A. Ripoli , C. L. Susini , L. Landini , D. Chiappino