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Nuclear segmentation and classification within Haematoxylin & Eosin stained histology images is a fundamental prerequisite in the digital pathology work-flow. The development of automated methods for nuclear segmentation and classification…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Simon Graham , Quoc Dang Vu , Shan E Ahmed Raza , Ayesha Azam , Yee Wah Tsang , Jin Tae Kwak , Nasir Rajpoot

Identification and quantification of nuclei in colorectal cancer haematoxylin \& eosin (H\&E) stained histology images is crucial to prognosis and patient management. In computational pathology these tasks are referred to as nuclear…

Quantitative Methods · Quantitative Biology 2022-03-08 Muhammad Dawood , Raja Muhammad Saad Bashir , Srijay Deshpande , Manahil Raza , Adam Shephard

Nuclear segmentation and classification is an essential step for computational pathology. TIA lab from Warwick University organized a nuclear segmentation and classification challenge (CoNIC) for H&E stained histopathology images in…

Image and Video Processing · Electrical Eng. & Systems 2022-03-22 Jijun Cheng , Xipeng Pan , Feihu Hou , Bingchao Zhao , Jiatai Lin , Zhenbing Liu , Zaiyi Liu , Chu Han

Accurate segmenting nuclei instances is a crucial step in computer-aided image analysis to extract rich features for cellular estimation and following diagnosis as well as treatment. While it still remains challenging because the wide…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Yanning Zhou , Omer Fahri Onder , Qi Dou , Efstratios Tsougenis , Hao Chen , Pheng-Ann Heng

Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology and patient outcome. To drive innovation in this area, we setup a community-wide challenge using…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Simon Graham , Quoc Dang Vu , Mostafa Jahanifar , Martin Weigert , Uwe Schmidt , Wenhua Zhang , Jun Zhang , Sen Yang , Jinxi Xiang , Xiyue Wang , Josef Lorenz Rumberger , Elias Baumann , Peter Hirsch , Lihao Liu , Chenyang Hong , Angelica I. Aviles-Rivero , Ayushi Jain , Heeyoung Ahn , Yiyu Hong , Hussam Azzuni , Min Xu , Mohammad Yaqub , Marie-Claire Blache , Benoît Piégu , Bertrand Vernay , Tim Scherr , Moritz Böhland , Katharina Löffler , Jiachen Li , Weiqin Ying , Chixin Wang , Dagmar Kainmueller , Carola-Bibiane Schönlieb , Shuolin Liu , Dhairya Talsania , Yughender Meda , Prakash Mishra , Muhammad Ridzuan , Oliver Neumann , Marcel P. Schilling , Markus Reischl , Ralf Mikut , Banban Huang , Hsiang-Chin Chien , Ching-Ping Wang , Chia-Yen Lee , Hong-Kun Lin , Zaiyi Liu , Xipeng Pan , Chu Han , Jijun Cheng , Muhammad Dawood , Srijay Deshpande , Raja Muhammad Saad Bashir , Adam Shephard , Pedro Costa , João D. Nunes , Aurélio Campilho , Jaime S. Cardoso , Hrishikesh P S , Densen Puthussery , Devika R G , Jiji C , Ye Zhang , Zijie Fang , Zhifan Lin , Yongbing Zhang , Chunhui Lin , Liukun Zhang , Lijian Mao , Min Wu , Vi Thi-Tuong Vo , Soo-Hyung Kim , Taebum Lee , Satoshi Kondo , Satoshi Kasai , Pranay Dumbhare , Vedant Phuse , Yash Dubey , Ankush Jamthikar , Trinh Thi Le Vuong , Jin Tae Kwak , Dorsa Ziaei , Hyun Jung , Tianyi Miao , David Snead , Shan E Ahmed Raza , Fayyaz Minhas , Nasir M. Rajpoot

Nuclear segmentation in histology images is a challenging task due to significant variations in the shape and appearance of nuclei. One of the main hurdles in nuclear instance segmentation is overlapping nuclei where a smart algorithm is…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Navid Alemi Koohbanani , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Nucleus segmentation and classification are the prerequisites in the workflow of digital pathology processing. However, it is very challenging due to its high-level heterogeneity and wide variations. This work proposes a deep neural network…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Sen Yang , Jinxi Xiang , Xiyue Wang

Nucleus image segmentation is a crucial step in the analysis, pathological diagnosis, and classification, which heavily relies on the quality of nucleus segmentation. However, the complexity of issues such as variations in nucleus size,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-11 Junzhou Chen , Qian Huang , Yulin Chen , Linyi Qian , Chengyuan Yu

We present a novel neural network architecture, US-Net, for robust nuclei instance segmentation in histopathology images. The proposed framework integrates the nuclei detection and segmentation networks by sharing their outputs through the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-04 Zhaoyang Xu , Faranak Sobhani , Carlos Fernandez Moro , Qianni Zhang

Nuclei classification provides valuable information for histopathology image analysis. However, the large variations in the appearance of different nuclei types cause difficulties in identifying nuclei. Most neural network based methods are…

Computer Vision and Pattern Recognition · Computer Science 2023-02-23 Wei Lou , Xiang Wan , Guanbin Li , Xiaoying Lou , Chenghang Li , Feng Gao , Haofeng Li

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu

Simultaneous segmentation and classification of nuclei in digital histology play an essential role in computer-assisted cancer diagnosis; however, it remains challenging. The highest achieved binary and multi-class Panoptic Quality (PQ)…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Ibtihaj Ahmad , Syed Muhammad Israr , Zain Ul Islam

Histopathology image synthesis aims to address the data shortage issue in training deep learning approaches for accurate cancer detection. However, existing methods struggle to produce realistic images that have accurate nuclei boundaries…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Sujata Butte , Haotian Wang , Aleksandar Vakanski , Min Xian

Manually annotating nuclei from the gigapixel Hematoxylin and Eosin (H&E)-stained Whole Slide Images (WSIs) is a laborious and costly task, meaning automated algorithms for cell nuclei instance segmentation and classification could…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 João D. Nunes , Diana Montezuma , Domingos Oliveira , Tania Pereira , Jaime S. Cardoso

Accurate detection and classification of nuclei in histopathology images are critical for diagnostic and research applications. We present KongNet, a multi-headed deep learning architecture featuring a shared encoder and parallel,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Jiaqi Lv , Esha Sadia Nasir , Kesi Xu , Mostafa Jahanifar , Brinder Singh Chohan , Behnaz Elhaminia , Shan E Ahmed Raza

Nuclei segmentation and classification is the first and most crucial step that is utilized for many different microscopy medical analysis applications. However, it suffers from many issues such as the segmentation of small objects,…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Hussam Azzuni , Muhammad Ridzuan , Min Xu , Mohammad Yaqub

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Satoshi Kondo , Satoshi Kasai

Efficient and precise classification of histological cell nuclei is of utmost importance due to its potential applications in the field of medical image analysis. It would facilitate the medical practitioners to better understand and…

Computer Vision and Pattern Recognition · Computer Science 2019-11-19 S H Shabbeer Basha , Soumen Ghosh , Kancharagunta Kishan Babu , Shiv Ram Dubey , Viswanath Pulabaigari , Snehasis Mukherjee

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Simon Graham , Mostafa Jahanifar , Quoc Dang Vu , Giorgos Hadjigeorghiou , Thomas Leech , David Snead , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot
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