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Breast cancer patients may experience relapse or death after surgery during the follow-up period, leading to dependent censoring of relapse. This phenomenon, known as semi-competing risk, imposes challenges in analyzing treatment effects on…

Methodology · Statistics 2024-07-03 Tonghui Yu , Mengjiao Peng , Yifan Cui , Elynn Chen , Chixiang Chen

We introduce a general class of continuous univariate distributions with positive support obtained by transforming the class of two-piece distributions. We show that this class of distributions is very flexible, easy to implement, and…

Applications · Statistics 2015-11-06 Francisco J. Rubio , Yili Hong

In fields such as hydrology and climatology, modelling the entire distribution of positive data is essential, as stakeholders require insights into the full range of values, from low to extreme. Traditional approaches often segment the…

Methodology · Statistics 2025-10-03 Carlo Gaetan , Philippe Naveau

The hazard function is central to the formulation of commonly used survival regression models such as the proportional hazards and accelerated failure time models. However, these models rely on a shared baseline hazard, which, when…

Methodology · Statistics 2025-12-19 J. A. Christen , F. J. Rubio

As a motivating problem, we aim to study some special aspects of the marginal distributions of the order statistics for exchangeable and (more generally) for minimally stable non-negative random variables $T_{1},...,T_{r}$. In any case, we…

Probability · Mathematics 2021-06-16 Rachele Foschi , Giovanna Nappo , Fabio L. Spizzichino

We propose an extension of the regular Cox's proportional hazards model which allows the estimation of the probabilities of rare events. It is known that when the data are heavily censored at the upper end of the survival distribution, the…

Methodology · Statistics 2019-01-23 Ion Grama , Kevin Jaunatre

Cardiovascular diseases are major causes of mortality globally. They often co-occur and are interrelated, leading to partial-order relationships among their onset times. However, these onset times are subject to informative censoring due to…

Methodology · Statistics 2026-04-07 Tonghui Yu , Liming Xiang

This paper deals with a situation when one is interested in the dependence structure of a multidimensional response variable in the presence of a multivariate covariate. It is assumed that the covariate affects only the marginal…

Statistics Theory · Mathematics 2019-03-12 Marek Omelka , Šárka Hudecová , Natalie Neumeyer

This paper considers the efficient estimation of copula-based semiparametric strictly stationary Markov models. These models are characterized by nonparametric invariant (one-dimensional marginal) distributions and parametric bivariate…

Statistics Theory · Mathematics 2009-11-20 Xiaohong Chen , Wei Biao Wu , Yanping Yi

Probability density estimation is a central task in statistics. Copula-based models provide a great deal of flexibility in modelling multivariate distributions, allowing for the specifications of models for the marginal distributions…

Methodology · Statistics 2024-05-08 Nicolás Kuschinski , Richard Warr , Alejandro Jara

The use of massive survival data has become common in survival analysis. In this study, a subsampling algorithm is proposed for the Cox proportional hazards model with time-dependent covariates when the sample is extraordinarily large but…

Computation · Statistics 2023-02-07 Nan Qiao , Wangcheng Li , Feng Xiao , Cunjie Lin , Yong Zhou

The Cox regression, a semi-parametric method of survival analysis, is extremely popular in biomedical applications. The proportional hazards assumption is a key requirement in the Cox model. To accommodate non-proportional hazards, we…

Methodology · Statistics 2022-06-13 Alexander Begun , Elena Kulinskaya

The non-identifiability of the competing risks model requires researchers to work with restrictions on the model to obtain informative results. We present a new identifiability solution based on an exclusion restriction. Many areas of…

Methodology · Statistics 2023-09-06 Munir Hiabu , Simon M. S. LU , Ralf A. Wilke

Survival models are a popular tool for the analysis of time to event data with applications in medicine, engineering, economics, and many more. Advances like the Cox proportional hazard model have enabled researchers to better describe…

Machine Learning · Statistics 2021-02-16 Stefan Groha , Sebastian M Schmon , Alexander Gusev

Understanding variable dependence, particularly eliciting their statistical properties given a set of covariates, provides the mathematical foundation in practical operations management such as risk analysis and decision-making given…

Methodology · Statistics 2023-09-06 Yunyun Wang , Tatsushi Oka , Dan Zhu

A typical situation in competing risks analysis is that the researcher is only interested in a subset of risks. This paper considers a depending competing risks model with the distribution of one risk being a parametric or semi-parametric…

Methodology · Statistics 2022-05-13 Simon M. S. Lo , Ralf A. Wilke

In medical studies, it is common the presence of a fraction of patients who do not experience the event of interest. These patients are people who are not at risk of the event or are patients who were cured during the research. The…

Extreme-value copulas arise as the limiting dependence structure of component-wise maxima. Defined in terms of a functional parameter, they are one of the most widespread copula families due to their flexibility and ability to capture…

Methodology · Statistics 2022-03-25 Javier Fernández Serrano

In the context of survival analysis, Marshall and Olkin (1997) introduced families of distributions by adding a scalar parameter to a given survival function, parameterized or not. In that paper, we generalize their approach. We show how it…

Methodology · Statistics 2011-07-21 Damien Bousquet , Jean-Pierre Daurès , Jean-Michel Marin

Continuous-time multi-state survival models can be used to describe health-related processes over time. In the presence of interval-censored times for transitions between the living states, the likelihood is constructed using transition…

Methodology · Statistics 2017-03-24 Robson J. M. Machado , Ardo van den Hout