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We disclose the generality of the intrinsic mechanisms underlying multistability in reciprocally inhibitory 3-cell circuits composed of simplified, low-dimensional models of oscillatory neurons, as opposed to those of a detailed Hodgkin-…

Adaptation and Self-Organizing Systems · Physics 2020-08-26 J. Collens , K. Pusuluri , A. Kelly , D. Knapper , T. Xing , S. Basodi , D. Alacam , A. L. Shilnikov

We study a simplified stochastic model for the vascularization of a growing tumor, incorporating the formation of new blood vessels at the tumor periphery as well as their regression in the tumor center. The resulting morphology of the…

Cell Behavior · Quantitative Biology 2009-09-16 Raja Paul

Contemporary paradigm of vascular hemodynamics considers normal blood flow to be pulsatile laminar flow. Transition to turbulence can cause diseases such as atherosclerosis or brain aneurysms. Recently, we demonstrated the existence of…

Hydrodynamic instabilities in miscible fluids are ubiquitous, from natural phenomena up to geological scales, to industrial and technological applications, where they represent the only way to control and promote mixing at low Reynolds…

Soft Condensed Matter · Physics 2017-12-21 Domenico Truzzolillo , Luca Cipelletti

Flows over remarkably long distances are crucial to the functioning of many organisms, across all kingdoms of life. Coordinated flows are fundamental to power deformations, required for migration or development, or to spread resources and…

Biological Physics · Physics 2018-10-19 Jean-Daniel Julien , Karen Alim

An exhaustive description of the dynamics under shear flow of a large number of red blood cells in dilute regime is proposed, which highlights and takes into account the dispersion in cell properties within a given blood sample.…

Biological Physics · Physics 2019-02-11 Christophe Minetti , Vassanti Audemar , Thomas Podgorski , Gwennou Coupier

Origin of hydrodynamic turbulence in rotating shear flows is investigated. The particular emphasis is the flows whose angular velocity decreases but specific angular momentum increases with increasing radial coordinate. Such flows are…

High Energy Astrophysical Phenomena · Physics 2013-02-19 Banibrata Mukhopadhyay , Amit K. Chattopadhyay

Resilience has become a key aspect in the design of contemporary infrastructure networks. This comes as a result of ever-increasing loads, limited physical capacity, and fast-growing levels of interconnectedness and complexity due to the…

Systems and Control · Computer Science 2019-01-29 Giacomo Como

A biological system achieve homeostasis when there is a regulated quantity that is maintained within a narrow range of values. Here we consider homeostasis as a phenomenon of network dynamics. In this context, we improve a general theory…

Molecular Networks · Quantitative Biology 2024-05-08 João Luiz de Oliveira Madeira , Fernando Antoneli

Viscous streaming refers to the rectified, steady flows that emerge when a liquid oscillates around an immersed microfeature, typically a solid body or a bubble. The ability of such features to locally concentrate stresses produces strong…

Organisms often use cyclic changes in the concentrations of chemicals species to precisely time biological functions. Underlying these biochemical clocks are chemical reactions and transport processes, which are inherently stochastic.…

Statistical Mechanics · Physics 2020-02-06 Clara del Junco , Suriyanarayanan Vaikuntanathan

Stochastic Structural Stability Theory (SSST) provides an autonomous, deterministic, nonlinear dynamical system for evolving the statistical mean state of a turbulent system. In this work SSST is applied to the problem of understanding the…

Fluid Dynamics · Physics 2014-12-30 Brian F. Farrell , Petros J. Ioannou

The propagation of traffic congestion along roads is a commonplace nonlinear phenomenon. When many roads are connected in a network, congestion can spill from one road to others as drivers queue to enter a congested road, creating further…

Systems and Control · Computer Science 2019-06-18 Matthew A. Wright , Roberto Horowitz , Alex A. Kurzhanskiy

Many natural systems are organized as networks, in which the nodes (be they cells, individuals or populations) interact in a time-dependent fashion. The dynamic behavior of these networks depends on how these nodes are connected, which can…

Neurons and Cognition · Quantitative Biology 2015-06-22 Anca Radulescu , Sergio Verduzco-Flores

In this work, we study the dynamical robustness in a system consisting of both active and inactive oscillators. We analytically show that the dynamical robustness of such system is determined by the cross link density between active and…

Adaptation and Self-Organizing Systems · Physics 2017-03-01 Wenwen Huang , Xiyun Zhang , Xin Hu , Zonghua Liu , Shuguang Guan

The stability of a flow of an electrically conducting, incompressible fluid in a channel with an imposed uniform wall-normal magnetic field and electrically insulating walls is studied using linear stability analysis and direct numerical…

Fluid Dynamics · Physics 2025-12-23 Roman Okatev , Oleg Zikanov , Dmitry Krasnov , Peter Frick

In this paper we use a continuous model to describe the development of a single cell lineage following the committal of stem cells. Three separate controls are implemented in the model, namely the proliferative control of stem cells, the…

Tissues and Organs · Quantitative Biology 2007-05-23 Ivana Drobnjak , A. C. Fowler , Michael C. Mackey

The theory of pattern formation in reaction-diffusion systems is extended to the case of a directed network. Due to the structure of the network Laplacian of the scrutinised system, the dispersion relation has both real and imaginary parts,…

Pattern Formation and Solitons · Physics 2014-08-01 Malbor Asllani , Joseph D. Challenger , Francesco Saverio Pavone , Leonardo Sacconi , Duccio Fanelli

We review the dynamical behavior of giant fluid vesicles in various types of external hydrodynamic flow. The interplay between stresses arising from membrane elasticity, hydrodynamic flows, and the ever present thermal fluctuations leads to…

Soft Condensed Matter · Physics 2014-05-12 David Abreu , Michael Levant , Victor Steinberg , Udo Seifert

Networks of strongly-coupled neurons with random connectivity exhibit chaotic, asynchronous fluctuations. In previous work, we showed that when endowed with an additional low-rank connectivity consisting of the outer product of orthogonal…

Neurons and Cognition · Quantitative Biology 2021-06-09 Itamar Daniel Landau , Haim Sompolinsky
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