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Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Satoshi Kondo , Satoshi Kasai

Digital pathology is one of the most significant developments in modern medicine. Pathological examinations are the gold standard of medical protocols and play a fundamental role in diagnosis. Recently, with the advent of digital scanners,…

Image and Video Processing · Electrical Eng. & Systems 2021-12-09 Mahdi Arab Loodaricheh , Nader Karimi , Shadrokh Samavi

Instance segmentation of nuclei and glands in the histology images is an important step in computational pathology workflow for cancer diagnosis, treatment planning and survival analysis. With the advent of modern hardware, the recent…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Esha Sadia Nasir , Arshi Perviaz , Muhammad Moazam Fraz

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Generally, microscopy image analysis in biology relies on the segmentation of individual nuclei, using a dedicated stained image, to identify individual cells. However stained nuclei have drawbacks like the need for sample preparation, and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Gendarme Mathieu , Lambert Annika M. , El Debs Bachir

Cancer is one of the leading causes of death in the developed world. Cancer diagnosis is performed through the microscopic analysis of a sample of suspicious tissue. This process is time consuming and error prone, but Deep Learning models…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Pedro Costa , Yongpan Fu , João Nunes , Aurélio Campilho , Jaime S. Cardoso

Segmentation and accurate localization of nuclei in histopathological images is a very challenging problem, with most existing approaches adopting a supervised strategy. These methods usually rely on manual annotations that require a lot of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Mihir Sahasrabudhe , Stergios Christodoulidis , Roberto Salgado , Stefan Michiels , Sherene Loi , Fabrice André , Nikos Paragios , Maria Vakalopoulou

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Weizhen Liu , Qian He , Xuming He

Nuclear segmentation and classification is an essential step for computational pathology. TIA lab from Warwick University organized a nuclear segmentation and classification challenge (CoNIC) for H&E stained histopathology images in…

Image and Video Processing · Electrical Eng. & Systems 2022-03-22 Jijun Cheng , Xipeng Pan , Feihu Hou , Bingchao Zhao , Jiatai Lin , Zhenbing Liu , Zaiyi Liu , Chu Han

With the advent of digital pathology and microscopic systems that can scan and save whole slide histological images automatically, there is a growing trend to use computerized methods to analyze acquired images. Among different…

Image and Video Processing · Electrical Eng. & Systems 2024-01-10 Amirreza Mahbod , Georg Dorffner , Isabella Ellinger , Ramona Woitek , Sepideh Hatamikia

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

Instance segmentation of overlapping objects in biomedical images remains a largely unsolved problem. We take up this challenge and present MultiStar, an extension to the popular instance segmentation method StarDist. The key novelty of our…

Computer Vision and Pattern Recognition · Computer Science 2021-01-15 Florin C. Walter , Sebastian Damrich , Fred A. Hamprecht

Deep learning-based methods are gaining traction in digital pathology, with an increasing number of publications and challenges that aim at easing the work of systematically and exhaustively analyzing tissue slides. These methods often…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ting-An Yen , Hung-Chun Hsu , Pushpak Pati , Maria Gabrani , Antonio Foncubierta-Rodríguez , Pau-Choo Chung

In this paper, we propose a new image instance segmentation method that segments individual glands (instances) in colon histology images. This is a task called instance segmentation that has recently become increasingly important. The…

Computer Vision and Pattern Recognition · Computer Science 2016-07-20 Yan Xu , Yang Li , Mingyuan Liu , Yipei Wang , Yubo Fan , Maode Lai , Eric I-Chao Chang

Identification and quantification of nuclei in colorectal cancer haematoxylin \& eosin (H\&E) stained histology images is crucial to prognosis and patient management. In computational pathology these tasks are referred to as nuclear…

Quantitative Methods · Quantitative Biology 2022-03-08 Muhammad Dawood , Raja Muhammad Saad Bashir , Srijay Deshpande , Manahil Raza , Adam Shephard

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu

Accurate detection and segmentation of cell nuclei in volumetric (3D) fluorescence microscopy datasets is an important step in many biomedical research projects. Although many automated methods for these tasks exist, they often struggle for…

Computer Vision and Pattern Recognition · Computer Science 2020-06-16 Martin Weigert , Uwe Schmidt , Robert Haase , Ko Sugawara , Gene Myers

We address the problem of automated nuclear segmentation, classification, and quantification from Haematoxylin and Eosin stained histology images, which is of great relevance for several downstream computational pathology applications. In…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Lihao Liu , Chenyang Hong , Angelica I. Aviles-Rivero , Carola-Bibiane Schönlieb

Nuclear segmentation in histology images is a challenging task due to significant variations in the shape and appearance of nuclei. One of the main hurdles in nuclear instance segmentation is overlapping nuclei where a smart algorithm is…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Navid Alemi Koohbanani , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Nuclear segmentation and classification within Haematoxylin & Eosin stained histology images is a fundamental prerequisite in the digital pathology work-flow. The development of automated methods for nuclear segmentation and classification…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Simon Graham , Quoc Dang Vu , Shan E Ahmed Raza , Ayesha Azam , Yee Wah Tsang , Jin Tae Kwak , Nasir Rajpoot
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