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Removing soft and self shadows that lack clear boundaries from a single image is still challenging. Self shadows are shadows that are cast on the object itself. Most existing methods rely on binary shadow masks, without considering the…
Accurate assessment of human epidermal growth factor receptor 2 (HER2) expression is critical for breast cancer diagnosis, prognosis, and therapy selection; yet, most existing digital HER2 scoring methods rely on bulky and expensive optical…
Increasing demand for understanding the vast heterogeneity of cellular phenotypes has driven the development of imaging flow cytometry (IFC), that combines features of flow cytometry with fluorescence and bright field microscopy. IFC…
Diffusion models excel at image restoration via probabilistic modeling of forward noise addition and reverse denoising, and their ability to handle complex noise while preserving fine details makes them well-suited for Low-Light Image…
This paper introduces the notion of soft bits to address the rate-distortion optimization for learning-based image compression. Recent methods for such compression train an autoencoder end-to-end with an objective to strike a balance…
Fluorescent imaging plays a critical role in a myriad of scientific endeavors, particularly in the biological sciences. Three-dimensional imaging of fluorescent intensity often requires serial data acquisition, that is voxel-by-voxel…
Digital Breast Tomosynthesis (DBT) is a widely used medical imaging modality for breast cancer screening and diagnosis, offering higher spatial resolution and greater detail through its 3D-like breast volume imaging capability. However, the…
Photoacoustic imaging (PAI) is a non-invasive imaging modality that detects the ultrasound signal generated from tissue with light excitation. Photoacoustic computed tomography (PACT) uses unfocused large-area light to illuminate the target…
We have developed an automatic method for segmenting fluorescence lifetime (FLT) imaging microscopy (FLIM) images of cells inspired by a multi-resolution community detection (MCD) based network segmentation method. The image processing…
Leukocyte differential test is a widely performed clinical procedure for screening infectious diseases. Existing hematology analyzers require labor-intensive work and a panel of expensive reagents. Here we report an artificial-intelligence…
This paper studies the problem of Line Segment Detection (LSD) for the characterization of line geometry in images, with the aim of learning a domain-agnostic robust LSD model that works well for any natural images. With the focus of…
Deep Learning in Image Registration (DLIR) methods have been tremendously successful in image registration due to their speed and ability to incorporate weak label supervision at training time. However, existing DLIR methods forego many of…
Machine learning based Single Image Intrinsic Decomposition (SIID) methods decompose a captured scene into its albedo and shading images by using the knowledge of a large set of known and realistic ground truth decompositions. Collecting…
While diffusion models have set a new benchmark for quality in Low-Dose Computed Tomography (LDCT) denoising, their clinical adoption is critically hindered by extreme computational costs, with inference times often exceeding thousands of…
Low-light image enhancement remains a challenging task, particularly in the absence of paired training data. In this study, we present LucentVisionNet, a novel zero-shot learning framework that addresses the limitations of traditional and…
Pretraining vision transformers (ViT) with attention guided masked image modeling (MIM) has shown to increase downstream accuracy for natural image analysis. Hierarchical shifted window (Swin) transformer, often used in medical image…
Low-dose computed tomography (LDCT) is the current standard for lung cancer screening, yet its adoption and accessibility remain limited. Many regions lack LDCT infrastructure, and even among those screened, early-stage cancer detection…
Low-light image enhancement (LLIE) is a crucial task in computer vision aimed at enhancing the visual fidelity of images captured under low-illumination conditions. Conventional methods frequently struggle with noise, overexposure, and…
Determining lymphoma subtypes is a crucial step for better patient treatment targeting to potentially increase their survival chances. In this context, the existing gold standard diagnosis method, which relies on gene expression technology,…
This paper introduces a novel framework for zero-shot learning (ZSL), i.e., to recognize new categories that are unseen during training, by using a multi-model and multi-alignment integration method. Specifically, we propose three…