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Measuring the impact of an environmental point source exposure on the risk of disease, like cancer or childhood asthma, is well-developed. Modeling how an environmental health hazard that is extensive in space, like a wastewater canal,…

Methodology · Statistics 2024-07-29 Rob Trangucci , Jesse Contreras , Jon Zelner , Joseph N. S. Eisenberg , Yang Chen

In this article, we analyze perinatal data with birth weight (BW) as primarily interesting response variable. Gestational age (GA) is usually an important covariate and included in polynomial form. However, in opposition to this univariate…

Methodology · Statistics 2021-11-02 Jonathan Rathjens , Arthur Kolbe , Jürgen Hölzer , Katja Ickstadt , Nadja Klein

Psychiatric and social epidemiology often involves assessing the effects of environmental exposure on outcomes that are difficult to measure directly. To address this problem, it is common to measure outcomes using a comprehensive battery…

Quantile regression is a powerful tool for inferring how covariates affect specific percentiles of the response distribution. Existing methods either estimate conditional quantiles separately for each quantile of interest or estimate the…

Methodology · Statistics 2024-11-19 Joseph Feldman , Daniel Kowal

While it is well known that high levels of prenatal alcohol exposure (PAE) result in significant cognitive deficits in children, the exact nature of the dose response is less well understood. In particular, there is a pressing need to…

We develop a fully Bayesian framework for function-on-scalars regression with many predictors. The functional data response is modeled nonparametrically using unknown basis functions, which produces a flexible and data-adaptive functional…

Methodology · Statistics 2018-10-25 Daniel R. Kowal , Daniel C. Bourgeois

This paper presents an approach to estimating the health effects of an environmental hazard. The approach is general in nature, but is applied here to the case of air pollution. It uses a computer model involving ambient pollution and…

Applications · Statistics 2007-11-01 Gavin Shaddick , Duncan Lee , James V. Zidek , Ruth Salway

Although most pregnancies result in a good outcome, complications are not uncommon and can be associated with serious implications for mothers and babies. Predictive modeling has the potential to improve outcomes through better…

Machine Learning · Computer Science 2023-10-18 Tomas M. Bosschieter , Zifei Xu , Hui Lan , Benjamin J. Lengerich , Harsha Nori , Ian Painter , Vivienne Souter , Rich Caruana

We develop a modeling framework for dynamic function-on-scalars regression, in which a time series of functional data is regressed on a time series of scalar predictors. The regression coefficient function for each predictor is allowed to…

Methodology · Statistics 2018-10-25 Daniel R. Kowal

The spread of PM2.5 pollutants that endanger health is difficult to predict because it involves many atmospheric variables. These micron particles can spread rapidly from their source to residential areas, increasing the risk of respiratory…

Machine Learning · Computer Science 2021-01-18 Hsing-Chung Chen , Karisma Trinanda Putra , Jerry Chun-WeiLin

Accounting for exposure measurement errors has been recognized as a crucial problem in environmental epidemiology for over two decades. Bayesian hierarchical models offer a coherent probabilistic framework for evaluating associations…

Methodology · Statistics 2024-01-17 Changwoo J. Lee , Elaine Symanski , Amal Rammah , Dong Hun Kang , Philip K. Hopke , Eun Sug Park

Estimation of the long-term health effects of air pollution is a challenging task, especially when modelling small-area disease incidence data in an ecological study design. The challenge comes from the unobserved underlying spatial…

Methodology · Statistics 2013-05-24 Duncan Lee , Alastair Rushworth , Sujit K. Sahu

Climate change impact studies inform policymakers on the estimated damages of future climate change on economic, health and other outcomes. In most studies, an annual outcome variable is observed, e.g. agricultural yield, along with a…

Methodology · Statistics 2023-04-24 Xiaomeng Cui , Bulat Gafarov , Dalia Ghanem , Todd Kuffner

Functional data describe a wide range of processes, such as growth curves and spectral absorption. In this study, we analyze air pollution data from the In-service Aircraft for a Global Observing System, focusing on the spatial interactions…

Methodology · Statistics 2024-11-14 Rita Fici , Gianluca Sottile , Luigi Augugliaro , Ernst-Jan Camiel Wit

Subset selection is a valuable tool for interpretable learning, scientific discovery, and data compression. However, classical subset selection is often avoided due to selection instability, lack of regularization, and difficulties with…

Machine Learning · Statistics 2022-02-17 Daniel R. Kowal

Understanding the role of time-varying pollution mixtures on human health is critical as people are simultaneously exposed to multiple pollutants during their lives. For vulnerable sub-populations who have well-defined exposure periods…

Residuals in regression models are often spatially correlated. Prominent examples include studies in environmental epidemiology to understand the chronic health effects of pollutants. I consider the effects of residual spatial structure on…

Methodology · Statistics 2010-11-05 Christopher J. Paciorek

This paper investigates whether associations between birth weight and prenatal ambient environmental conditions--pollution and extreme temperatures--differ by 1) maternal education; 2) children's innate health; and 3) interactions between…

General Economics · Economics 2022-04-04 Xiaoying Liu , Jere R. Behrman , Emily Hannum , Fan Wang , Qingguo Zhao

A typical problem in air pollution epidemiology is exposure assessment for individuals for which health data are available. Due to the sparsity of monitoring sites and the limited temporal frequency with which measurements of air pollutants…

We propose a new approach for estimating causal effects when the exposure is measured with error and confounding adjustment is performed via a generalized propensity score (GPS). Using validation data, we propose a regression calibration…