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We are interested in estimating the effect of a treatment applied to individuals at multiple sites, where data is stored locally for each site. Due to privacy constraints, individual-level data cannot be shared across sites; the sites may…

Machine Learning · Computer Science 2023-04-04 Ruoxuan Xiong , Allison Koenecke , Michael Powell , Zhu Shen , Joshua T. Vogelstein , Susan Athey

With the rapid digitalization of healthcare systems, there has been a substantial increase in the generation and sharing of private health data. Safeguarding patient information is essential for maintaining consumer trust and ensuring…

Artificial Intelligence · Computer Science 2026-01-27 Yazan Otoum , Amiya Nayak

Many modern applications collect data that comes in federated spirit, with data kept locally and undisclosed. Till date, most insight into the causal inference requires data to be stored in a central repository. We present a novel framework…

Methodology · Statistics 2021-06-02 Thanh Vinh Vo , Trong Nghia Hoang , Young Lee , Tze-Yun Leong

Connected health is a multidisciplinary approach focused on health management, prioritizing pa-tient needs in the creation of tools, services, and treatments. This paradigm ensures proactive and efficient care by facilitating the timely…

Computers and Society · Computer Science 2025-10-13 Mira Raheem , Michael Papazoglou , Bernd Krämer , Neamat El-Tazi , Amal Elgammal

Decentralized data sources are prevalent in real-world applications, posing a formidable challenge for causal inference. These sources cannot be consolidated into a single entity owing to privacy constraints. The presence of dissimilar data…

Machine Learning · Computer Science 2024-05-31 Thanh Vinh Vo , Young lee , Tze-Yun Leong

Privacy data protection in the medical field poses challenges to data sharing, limiting the ability to integrate data across hospitals for training high-precision auxiliary diagnostic models. Traditional centralized training methods are…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Tian Bowen , Xu Zhengyang , Yin Zhihao , Wang Jingying , Yue Yutao

Patient privacy is a major barrier to healthcare AI. For confidentiality reasons, most patient data remains in silo in separate hospitals, preventing the design of data-driven healthcare AI systems that need large volumes of patient data to…

Machine Learning · Computer Science 2023-10-11 Tatsuki Koga , Kamalika Chaudhuri , David Page

Prevention of stroke with its associated risk factors has been one of the public health priorities worldwide. Emerging artificial intelligence technology is being increasingly adopted to predict stroke. Because of privacy concerns, patient…

Machine Learning · Computer Science 2020-12-16 Ce Ju , Ruihui Zhao , Jichao Sun , Xiguang Wei , Bo Zhao , Yang Liu , Hongshan Li , Tianjian Chen , Xinwei Zhang , Dashan Gao , Ben Tan , Han Yu , Chuning He , Yuan Jin

Causal discovery serves a pivotal role in mitigating model uncertainty through recovering the underlying causal mechanisms among variables. In many practical domains, such as healthcare, access to the data gathered by individual entities is…

Machine Learning · Computer Science 2024-02-13 Amin Abyaneh , Nino Scherrer , Patrick Schwab , Stefan Bauer , Bernhard Schölkopf , Arash Mehrjou

Online collaborative medical prediction platforms offer convenience and real-time feedback by leveraging massive electronic health records. However, growing concerns about privacy and low prediction quality can deter patient participation…

Machine Learning · Computer Science 2025-07-16 Shao-Bo Lin , Xiaotong Liu , Yao Wang

Cardiovascular diseases are a leading cause of mortality worldwide, highlighting the need for accurate diagnostic methods. This study benchmarks centralized and federated machine learning algorithms for heart disease classification using…

Machine Learning · Computer Science 2024-08-19 Mario Padilla Rodriguez , Mohamed Nafea

Healthcare decision-making requires not only accurate predictions but also insights into how factors influence patient outcomes. While traditional Machine Learning (ML) models excel at predicting outcomes, such as identifying high risk…

Machine Learning · Computer Science 2025-01-28 Sheresh Zahoor , Pietro Liò , Gaël Dias , Mohammed Hasanuzzaman

With the rapid development of computer software and hardware technologies, more and more healthcare data are becoming readily available from clinical institutions, patients, insurance companies and pharmaceutical industries, among others.…

Machine Learning · Computer Science 2020-08-24 Jie Xu , Benjamin S. Glicksberg , Chang Su , Peter Walker , Jiang Bian , Fei Wang

Data sharing barriers are paramount challenges arising from multicenter clinical trials where multiple data sources are stored in a distributed fashion at different local study sites. Merging such data sources into a common data storage for…

Methodology · Statistics 2022-04-05 Mengtong Hu , Xu Shi , Peter X. -K. Song

The increased availability of medical data has significantly impacted healthcare by enabling the application of machine / deep learning approaches in various instances. However, medical datasets are usually small and scattered across…

Healthcare institutions have access to valuable patient data that could be of great help in the development of improved diagnostic models, but privacy regulations like HIPAA and GDPR prevent hospitals from directly sharing data with one…

Machine Learning · Computer Science 2026-01-27 Farzam Asad , Junaid Saif Khan , Maria Tariq , Sundus Munir , Muhammad Adnan Khan

Differential privacy is the leading mathematical framework for privacy protection, providing a probabilistic guarantee that safeguards individuals' private information when publishing statistics from a dataset. This guarantee is achieved by…

Methodology · Statistics 2025-08-19 Yuki Ohnishi , Jordan Awan

In clinical research, the lack of events of interest often necessitates imbalanced learning. One approach to resolve this obstacle is data integration or sharing, but due to privacy concerns neither is practical. Therefore, there is an…

Machine Learning · Computer Science 2020-09-01 Seok-Ju Hahn , Junghye Lee

Causal inference across multiple data sources offers a promising avenue to enhance the generalizability and replicability of scientific findings. However, data integration methods for time-to-event outcomes, common in biomedical research,…

Methodology · Statistics 2025-05-16 Yi Liu , Alexander W. Levis , Ke Zhu , Shu Yang , Peter B. Gilbert , Larry Han

The use of collaborative and decentralized machine learning techniques such as federated learning have the potential to enable the development and deployment of clinical risk predictions models in low-resource settings without requiring…

Machine Learning · Computer Science 2019-11-15 Stephen R. Pfohl , Andrew M. Dai , Katherine Heller
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