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In this work, we present a computational fluid-structure interaction (FSI) study for a healthy patient-specific pulmonary arterial tree using the unified continuum and variational multiscale (VMS) formulation we previously developed. The…

Computational Physics · Physics 2020-08-19 Ju Liu , Weiguang Yang , Ingrid S. Lan , Alison L. Marsden

We recently demonstrated the reduction of the unified continuum and variational multiscale formulation to a computationally efficient fluid-structure interaction (FSI) formulation via three sound modeling assumptions pertaining to the…

Medical Physics · Physics 2022-01-12 Ingrid S. Lan , Ju Liu , Weiguang Yang , Alison L. Marsden

We propose a computational framework for vascular fluid-structure interaction (FSI), focusing on biomechanical modeling, geometric modeling, and solver technology. The biomechanical model is constructed based on the unified continuum…

Fluid Dynamics · Physics 2022-06-27 Ju Liu , Jiayi Huang , Qingshuang Lu , Yujie Sun

We recently derived the unified continuum and variational multiscale formulation for fluid-structure interaction (FSI) using the Gibbs free energy. Restricting our attention to vascular FSI, we now reduce this arbitrary Lagrangian-Eulerian…

Computational Physics · Physics 2022-04-06 Ingrid S. Lan , Ju Liu , Weiguang Yang , Alison L. Marsden

Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by…

Accurate simulation of blood flow in deformable vessels is critical in cardiovascular research for understanding disease progression and informing clinical decision-making. However, due to the thin-walled nature of arteries, traditional…

Computational Engineering, Finance, and Science · Computer Science 2026-01-05 Chenxi Zhao , Dong Wu , Weiyi Kong , Oskar J. Haidn , Xiangyu Hu

The immersed boundary (IB) method is a mathematical framework for fluid-structure interaction problems (FSI) that was originally developed to simulate flows around heart valves. Direct comparison of FSI simulations around heart valves…

Fluid-Structure Interaction (FSI) can be investigated by means of non-linear Finite Element Models (FEM), suitable to capture large deflections of structural parts interacting with fluids, and Computational Fluid Dynamics (CFD). High…

A patient-specific fluid-structure interaction (FSI) model of a phase-contrast magnetic resonance angiography (PC-MRA) imaged arteriovenous fistula is presented. The numerical model is developed and simulated using a commercial multiphysics…

Medical Physics · Physics 2018-01-30 W. P. Guess , B. D. Reddy , A. McBride , B. Spottiswoode , J. Downs , T. Franz

Systematic in vivo validations of computational models of the aortic valve remain scarce, despite successful validation against in vitro data. Utilizing a combination of computed tomography and 4D flow magnetic resonance imaging data, we…

We present a new model and a novel loosely coupled partitioned numerical scheme modeling fluid-structure interaction (FSI) in blood flow allowing non-zero longitudinal displacement. Arterial walls are modeled by a {linearly viscoelastic,…

Numerical Analysis · Mathematics 2015-06-05 Martina Bukac , Suncica Canic , Roland Glowinski , Josip Tambaca , Annalisa Quaini

The analysis of quantitative hemodynamics and luminal pressure may add valuable information to aid treatment strategies and prognosis for aortic dissections. This work directly compared in vitro 4D-flow magnetic resonance imaging (MRI),…

We report a novel physics-informed neural framework for reconstructing unsteady fluid-structure interactions (FSI) from sparse, single-phase observations of the flow. Our approach combines a modal surface model with coordinate neural…

Fluid Dynamics · Physics 2026-04-07 Rui Tang , Ke Zhou , Jifu Tan , Samuel J. Grauer

We implement full, three-dimensional constrained mixture theory for vascular growth and remodeling into a finite element fluid-structure interaction (FSI) solver. The resulting "fluid-solid-growth" (FSG) solver allows long term,…

Computational Engineering, Finance, and Science · Computer Science 2023-08-11 Erica L. Schwarz , Martin R. Pfaller , Jason M. Szafron , Marcos Latorre , Stephanie E. Lindsey , Christopher K. Breuer , Jay D. Humphrey , Alison L. Marsden

We study a nonlinear, unsteady, moving boundary, fluid-structure interaction (FSI) problem arising in modeling blood flow through elastic and viscoelastic arteries. The fluid flow, which is driven by the time-dependent pressure data, is…

Analysis of PDEs · Mathematics 2015-06-05 Boris Muha , Suncica Canic

Computational ultrasound imaging (cUSi) with few elements and spatial field encoding can provide high-resolution volumetric B-mode imaging. In this work, we extend its application to 4D carotid artery (CA) flow imaging using a custom…

Background and Objective: Hemodynamic analysis of blood flow through arteries and veins is critical for diagnosing cardiovascular diseases, such as aneurysms and stenoses, and for investigating cardiovascular parameters, such as turbulence…

We develop a theory of fluid--structure interaction (FSI) between an oscillatory Newtonian fluid flow and a compliant conduit. We consider the canonical geometries of a 2D channel with a deformable top wall and an axisymmetric deformable…

Fluid Dynamics · Physics 2023-12-22 Shrihari D. Pande , Xiaojia Wang , Ivan C. Christov

Fluid-structure interaction (FSI) modeling, a technique widely used to enhance imaging modalities for adult and pediatric heart diseases, has been underutilized in the context of fetal circulation because of limited data on flow conditions…

Medical Physics · Physics 2024-10-29 Zhenglun Alan Wei , Guihong Chen , Biao Si , Liqun Sun , Mike Seed , Shuping Ge

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Computational Physics · Physics 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai
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