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Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen

Recognizing atypical mitotic figures in histopathology images allows physicians to correctly assess tumor aggressiveness. Although machine learning models could be exploited for automatically performing such a task, under domain shift these…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 Gennaro Percannella , Mattia Sarno , Francesco Tortorella , Mario Vento

Background: We aim to develop enriched radiomics features that integrate classical structural radiomics with novel functional radiomics derived from liver MRI for diagnosis and risk stratification in liver cancer. The proposed framework…

Stereotactic radiosurgery is a minimally-invasive treatment option for a large number of patients with intracranial tumors. As part of the therapy treatment, accurate delineation of brain tumors is of great importance. However,…

Acquiring properly annotated data is expensive in the medical field as it requires experts, time-consuming protocols, and rigorous validation. Active learning attempts to minimize the need for large annotated samples by actively sampling…

Image and Video Processing · Electrical Eng. & Systems 2023-06-22 Bidur Khanal , Binod Bhattarai , Bishesh Khanal , Danail Stoyanov , Cristian A. Linte

We developed a deep ensemble learning model with a radiomics spatial encoding execution for improved glioma segmentation accuracy using multi-parametric MRI (mp-MRI). This model was developed using 369 glioma patients with a 4-modality…

Quantitative Methods · Quantitative Biology 2023-03-21 Yang Chen , Zhenyu Yang , Jingtong Zhao , Justus Adamson , Yang Sheng , Fang-Fang Yin , Chunhao Wang

The diagnosis of the presence of metastatic lymph nodes from abdominal computed tomography (CT) scans is an essential task performed by radiologists to guide radiation and chemotherapy treatment. State-of-the-art deep learning classifiers…

Computer Vision and Pattern Recognition · Computer Science 2019-10-24 Saskia Glaser , Gabriel Maicas , Sergei Bedrikovetski , Tarik Sammour , Gustavo Carneiro

Objective: Deep Learning-based Radiomics (DLR) has achieved great success in medical image analysis and has been considered a replacement for conventional radiomics that relies on handcrafted features. In this study, we aimed to explore the…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Bingxin Gu , Mingyuan Meng , Lei Bi , Jinman Kim , David Dagan Feng , Shaoli Song

Adopting Convolutional Neural Networks (CNNs) in the daily routine of primary diagnosis requires not only near-perfect precision, but also a sufficient degree of generalization to data acquisition shifts and transparency. Existing CNN…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Mara Graziani , Sebastian Otalora , Stephane Marchand-Maillet , Henning Muller , Vincent Andrearczyk

For predicting cancer survival outcomes, standard approaches in clinical research are often based on two main modalities: pathology images for observing cell morphology features, and genomic (e.g., bulk RNA-seq) for quantifying gene…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hongxiao Wang , Yang Yang , Zhuo Zhao , Pengfei Gu , Nishchal Sapkota , Danny Z. Chen

Radiomic representations can quantify properties of regions of interest in medical image data. Classically, they account for pre-defined statistics of shape, texture, and other low-level image features. Alternatively, deep learning-based…

Computer Vision and Pattern Recognition · Computer Science 2021-07-14 Hongwei Li , Fei-Fei Xue , Krishna Chaitanya , Shengda Luo , Ivan Ezhov , Benedikt Wiestler , Jianguo Zhang , Bjoern Menze

Surgical tool segmentation in endoscopic images is an important problem: it is a crucial step towards full instrument pose estimation and it is used for integration of pre- and intra-operative images into the endoscopic view. While many…

Computer Vision and Pattern Recognition · Computer Science 2020-07-10 Daniil Pakhomov , Wei Shen , Nassir Navab

Automated analysis of chest radiography using deep learning has tremendous potential to enhance the clinical diagnosis of diseases in patients. However, deep learning models typically require large amounts of annotated data to achieve high…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Keegan Quigley , Miriam Cha , Ruizhi Liao , Geeticka Chauhan , Steven Horng , Seth Berkowitz , Polina Golland

Brain tumor segmentation is a critical task for tumor volumetric analyses and AI algorithms. However, it is a time-consuming process and requires neuroradiology expertise. While there has been extensive research focused on optimizing brain…

Image and Video Processing · Electrical Eng. & Systems 2021-12-01 Partoo Vafaeikia , Matthias W. Wagner , Uri Tabori , Birgit B. Ertl-Wagner , Farzad Khalvati

In this work we show preliminary results of deep multi-task learning in the area of computational pathology. We combine 11 tasks ranging from patch-wise oral cancer classification, one of the most prevalent cancers in the developing world,…

Computer Vision and Pattern Recognition · Computer Science 2020-05-19 Jevgenij Gamper , Navid Alemi Kooohbanani , Nasir Rajpoot

Purpose: AI in radiology is hindered chiefly by: 1) Requiring large annotated data sets. 2) Non-generalizability that limits deployment to new scanners / institutions. And 3) Inadequate explainability and interpretability. We believe that…

Artificial Intelligence · Computer Science 2020-08-07 Joseph Stember , Hrithwik Shalu

Lung cancer has the highest mortality rate of deadly cancers in the world. Early detection is essential to treatment of lung cancer. However, detection and accurate diagnosis of pulmonary nodules depend heavily on the experiences of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Chenglong Wang , Yun Liu , Fen Wang , Chengxiu Zhang , Yida Wang , Mei Yuan , Guang Yang

We propose a novel semi-supervised image segmentation method that simultaneously optimizes a supervised segmentation and an unsupervised reconstruction objectives. The reconstruction objective uses an attention mechanism that separates the…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Shuai Chen , Gerda Bortsova , Antonio Garcia-Uceda Juarez , Gijs van Tulder , Marleen de Bruijne

Automated segmentation of Pancreatic Ductal Adenocarcinoma (PDAC) from MRI is critical for clinical workflows but is hindered by poor tumor-tissue contrast and a scarcity of annotated data. This paper details our submission to the PANTHER…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Omer Faruk Durugol , Maximilian Rokuss , Yannick Kirchhoff , Klaus H. Maier-Hein

Head and neck tumors and metastatic lymph nodes are crucial for treatment planning and prognostic analysis. Accurate segmentation and quantitative analysis of these structures require pixel-level annotation, making automated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 Litingyu Wang , Wenjun Liao , Shichuan Zhang , Guotai Wang