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Diffusion magnetic resonance imaging (dMRI) enables non-invasive investigation of tissue microstructure. The Standard Model (SM) of white matter aims to disentangle dMRI signal contributions from intra- and extra-axonal water compartments.…

Image and Video Processing · Electrical Eng. & Systems 2026-04-15 Tom Hendriks , Gerrit Arends , Edwin Versteeg , Anna Vilanova , Maxime Chamberland , Chantal M. W. Tax

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang

White matter tract integrity (WMTI) can characterize brain microstructure in areas with highly aligned fiber bundles. Several WMTI biomarkers have now been validated against microscopy and provided promising results in studies of brain…

The noise in diffusion-weighted images (DWIs) decreases the accuracy and precision of diffusion tensor magnetic resonance imaging (DTI) derived microstructural parameters and leads to prolonged acquisition time for achieving improved…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Qiyuan Tian , Ziyu Li , Qiuyun Fan , Jonathan R. Polimeni , Berkin Bilgic , David H. Salat , Susie Y. Huang

Diffusion tensor imaging (DTI) is a widely used method for studying brain white matter development and degeneration. However, standard DTI estimation methods depend on a large number of high-quality measurements. This would require long…

Image and Video Processing · Electrical Eng. & Systems 2022-11-16 Davood Karimi , Ali Gholipour

High-resolution diffusion tensor imaging (DTI) is beneficial for probing tissue microstructure in fine neuroanatomical structures, but long scan times and limited signal-to-noise ratio pose significant barriers to acquiring DTI at…

Image and Video Processing · Electrical Eng. & Systems 2021-02-19 Qiyuan Tian , Ziyu Li , Qiuyun Fan , Chanon Ngamsombat , Yuxin Hu , Congyu Liao , Fuyixue Wang , Kawin Setsompop , Jonathan R. Polimeni , Berkin Bilgic , Susie Y. Huang

Estimating intra- and extra-axonal microstructure parameters, such as volume fractions and diffusivities, has been one of the major efforts in brain microstructure imaging with MRI. The Standard Model (SM) of diffusion in white matter has…

Diffusion MRI affords valuable insights into white matter microstructures, but suffers from low signal-to-noise ratio (SNR), especially at high diffusion weighting (i.e., b-value). To avoid time-intensive repeated acquisition,…

Medical Physics · Physics 2018-07-26 Geng Chen , Yafeng Wu , Dinggang Shen , Pew-Thian Yap

Tract-specific diffusion measures, as derived from brain diffusion MRI, have been linked to white matter tract structural integrity and neurodegeneration. As a consequence, there is a large interest in the automatic segmentation of white…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Bo Li , Marius de Groot , Meike Vernooij , Arfan Ikram , Wiro Niessen , Esther Bron

Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological…

Computer Vision and Pattern Recognition · Computer Science 2025-03-06 Yiqiong Yang , Yitian Yuan , Baoxing Ren , Ye Wu , Yanqiu Feng , Xinyuan Zhang

White matter (WM) tract segmentation is a crucial step for brain connectivity studies. It is performed on diffusion magnetic resonance imaging (dMRI), and deep neural networks (DNNs) have achieved promising segmentation accuracy. Existing…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Wan Liu , Chuyang Ye

We present DeepTract, a deep-learning framework for estimating white matter fibers orientation and streamline tractography. We adopt a data-driven approach for fiber reconstruction from diffusion weighted images (DWI), which does not assume…

Computer Vision and Pattern Recognition · Computer Science 2019-10-18 Itay Benou , Tammy Riklin-Raviv

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Diffusion-weighted magnetic resonance imaging in brain white matter probes tissue microstructure and allows for the estimation of compartmental diffusion parameters. Recently, it became apparent that traditional single-direction diffusion…

Biological Physics · Physics 2018-09-20 Marco Reisert , Valerij G. Kiselev , Bibek Dhital

Nonlinear methods such as Deep Neural Networks (DNNs) are the gold standard for various challenging machine learning problems, e.g., image classification, natural language processing or human action recognition. Although these methods…

Machine Learning · Computer Science 2017-11-15 Grégoire Montavon , Sebastian Bach , Alexander Binder , Wojciech Samek , Klaus-Robert Müller

Diffusion-weighted imaging (DWI) is a type of Magnetic Resonance Imaging (MRI) technique sensitised to the diffusivity of water molecules, offering the capability to inspect tissue microstructures and is the only in-vivo method to…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Sheng Chen , Zihao Tang , Mariano Cabezas , Xinyi Wang , Arkiev D'Souza , Michael Barnett , Fernando Calamante , Weidong Cai , Chenyu Wang

Deep learning has shown great potential in accelerating diffusion tensor imaging (DTI). Nevertheless, existing methods tend to suffer from Rician noise and eddy current, leading to detail loss in reconstructing the DTI-derived parametric…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Wenxin Fan , Jian Cheng , Cheng Li , Jing Yang , Ruoyou Wu , Juan Zou , Shanshan Wang

Deep learning has shown great potential in accelerating diffusion tensor imaging (DTI). Nevertheless, existing methods tend to suffer from Rician noise and detail loss in reconstructing the DTI-derived parametric maps especially when…

Computer Vision and Pattern Recognition · Computer Science 2024-01-04 Wenxin Fan , Jian Cheng , Cheng Li , Xinrui Ma , Jing Yang , Juan Zou , Ruoyou Wu , Qiegen Liu , Shanshan Wang

Neurite Orientation Dispersion and Density Imaging (NODDI) is an important imaging technology used to evaluate the microstructure of brain tissue, which is of great significance for the discovery and treatment of various neurological…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Taohui Xiao , Jian Cheng , Wenxin Fan , Jing Yang , Cheng Li , Enqing Dong , Shanshan Wang

Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 William Consagra , Lipeng Ning , Yogesh Rathi
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