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Embryo quality assessment after in vitro fertilization (IVF) is primarily done visually by embryologists. Variability among assessors, however, remains one of the main causes of the low success rate of IVF. This study aims to develop an…

Image and Video Processing · Electrical Eng. & Systems 2020-08-31 Ali Akbar Septiandri , Ade Jamal , Pritta Ameilia Iffanolida , Oki Riayati , Budi Wiweko

In vitro fertilization (IVF) is a widely utilized assisted reproductive technology, yet predicting its success remains challenging due to the multifaceted interplay of clinical, demographic, and procedural factors. This study develops a…

Time-lapse is a technology used to record the development of embryos during in-vitro fertilization (IVF). Accurate classification of embryo early development stages can provide embryologists valuable information for assessing the embryo…

Image and Video Processing · Electrical Eng. & Systems 2019-08-27 Zihan Liu , Bo Huang , Yuqi Cui , Yifan Xu , Bo Zhang , Lixia Zhu , Yang Wang , Lei Jin , Dongrui Wu

The application of artificial intelligence (AI) in IVF has shown promise in improving consistency and standardization of decisions, but often relies on annotated data and does not make use of the multimodal nature of IVF data. We…

Artificial Intelligence · Computer Science 2026-04-24 Nicklas Neu , Thomas Ebner , Jasmin Primus , Raphael Zefferer , Bernhard Schenkenfelder , Mathias Brunbauer , Florian Kromp

Assessing and selecting the most viable embryos for transfer is an essential part of in vitro fertilization (IVF). In recent years, several approaches have been made to improve and automate the procedure using artificial intelligence (AI)…

Machine Learning · Computer Science 2022-04-06 Jørgen Berntsen , Jens Rimestad , Jacob Theilgaard Lassen , Dang Tran , Mikkel Fly Kragh

Embryo selection is one of multiple crucial steps in in-vitro fertilization, commonly based on morphological assessment by clinical embryologists. Although artificial intelligence methods have demonstrated their potential to support embryo…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nicklas Neu , Thomas Ebner , Jasmin Primus , Bernhard Schenkenfelder , Raphael Zefferer , Mathias Brunbauer , Florian Kromp

The process of fertilizing a human egg outside the body in order to help those suffering from infertility to conceive is known as in vitro fertilization (IVF). Despite being the most effective method of assisted reproductive technology…

Infertility has a considerable impact on individuals' quality of life, affecting them socially and psychologically, with projections indicating a rise in the upcoming years. In vitro fertilization (IVF) emerges as one of the primary…

A critical factor that influences the success of an in-vitro fertilization (IVF) procedure is the quality of the transferred embryo. Embryo morphology assessments, conventionally performed through manual microscopic analysis suffer from…

In clinical In-Vitro Fertilization (IVF), identifying the most viable embryo for transfer is important to increasing the likelihood of a successful pregnancy. Traditionally, this process involves embryologists manually assessing embryos'…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Junsik Kim , Zhiyi Shi , Davin Jeong , Johannes Knittel , Helen Y. Yang , Yonghyun Song , Wanhua Li , Yicong Li , Dalit Ben-Yosef , Daniel Needleman , Hanspeter Pfister

Identification of fine-grained embryo developmental stages during In Vitro Fertilization (IVF) is crucial for assessing embryo viability. Although recent deep learning methods have achieved promising accuracy, existing discriminative models…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Yong Sun , Zhengjie Zhang , Junyu Shi , Zhiyuan Zhang , Lijiang Liu , Qiang Nie

A major challenge in clinical In-Vitro Fertilization (IVF) is selecting the highest quality embryo to transfer to the patient in the hopes of achieving a pregnancy. Time-lapse microscopy provides clinicians with a wealth of information for…

Infertility, a pressing global health concern, affects a substantial proportion of individuals worldwide. While advancements in assisted reproductive technology (ART) have offered effective interventions, conventional in vitro…

Artificial Intelligence · Computer Science 2025-09-25 Xueqiang Ouyang , Jia Wei

The selection of the optimal embryo for transfer is a critical yet challenging step in in vitro fertilization (IVF), primarily due to its reliance on the manual inspection of extensive time-lapse imaging data. A key obstacle in this process…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Zahra Asghari Varzaneh , Niclas Wölner-Hanssen , Reza Khoshkangini , Thomas Ebner , Magnus Johnsson

Temporal embryo images and parental fertility table indicators are both valuable for pregnancy prediction in \textbf{in vitro fertilization embryo transfer} (IVF-ET). However, current machine learning models cannot make full use of the…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Xueqiang Ouyang , Jia Wei , Wenjie Huo , Xiaocong Wang , Rui Li , Jianlong Zhou

In vitro fertilization (IVF) comprises a sequence of interventions concerned with the creation and culture of embryos which are then transferred to the patient's uterus. While the clinically important endpoint is birth, the responses to…

Applications · Statistics 2020-10-21 Jack Wilkinson , Stephen A Roberts , Andy Vail

Accurate embryo morphology assessment is essential in assisted reproductive technology for selecting the most viable embryo. Artificial intelligence has the potential to enhance this process. However, the limited availability of embryo data…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Oriana Presacan , Alexandru Dorobantiu , Vajira Thambawita , Michael A. Riegler , Mette H. Stensen , Mario Iliceto , Alexandru C. Aldea , Akriti Sharma

Macroscopic, phenomenological models have proven useful as concise framings of our understandings in fields from statistical physics to economics to biology. Constructing a phenomenological model for development would provide a framework…

Cell Behavior · Quantitative Biology 2021-03-24 Brian D Leahy , Catherine Racowsky , Daniel Needleman

Artificial intelligence (AI) has emerged as a powerful tool to enhance decision-making and optimize treatment protocols in in vitro fertilization (IVF). In particular, AI shows significant promise in supporting decision-making during the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Jana Zakall , Birgit Pohn , Antonia Graf , Daniel Kovatchki , Arezoo Borji , Ragib Shahriar Islam , Hossam Haick , Heinz Strohmer , Sepideh Hatamikia

In conventional clinical in-vitro fertilization practices embryos are transferred either at the cleavage or blastocyst stages of development. Cleavage stage transfers, particularly, are beneficial for patients with relatively poor prognosis…

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