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Scientists construct connectomes, comprehensive descriptions of neuronal connections across a brain, in order to better understand and model brain function. Interactive visualizations of these pathways would enable exploratory analysis of…

Neurons and Cognition · Quantitative Biology 2022-05-06 Seth Daetwiler , Angus Read , Jessica Stillwell , Kameron Decker Harris

Mammalian whole-brain connectomes are a foundational ingredient for holistic understanding of brains. Indeed, imaging connectomes at sufficient resolution to densely reconstruct cellular morphology and synapses represents a longstanding…

Neurons and Cognition · Quantitative Biology 2025-02-03 Logan Thrasher Collins , Todd Huffman , Randal Koene

Cognitive task classification using machine learning plays a central role in decoding brain states from neuroimaging data. By integrating machine learning with brain network analysis, complex connectivity patterns can be extracted from…

Machine Learning · Computer Science 2026-01-01 Debasis Maji , Arghya Banerjee , Debaditya Barman

One of the central objectives of contemporary neuroimaging research is to create predictive models that can disentangle the connection between patterns of functional connectivity across the entire brain and various behavioral traits.…

Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the underlying anatomical or structural network of synaptic connections. This latter is well…

Disordered Systems and Neural Networks · Physics 2021-02-11 Ali Safari , Paolo Moretti , Ibai Diez , Jesus M. Cortes , Miguel Ángel Muñoz

Effective analysis in neuroscience benefits significantly from robust conceptual frameworks. Traditional metrics of interbrain synchrony in social neuroscience typically depend on fixed, correlation-based approaches, restricting their…

Neurons and Cognition · Quantitative Biology 2025-12-01 Nicolás Hinrichs , Noah Guzmán , Melanie Weber

The human connectome represents a network map of the brain's wiring diagram and the pattern into which its connections are organized is thought to play an important role in cognitive function. The generative rules that shape the topology of…

Top-down feedback in cortex is critical for guiding sensory processing, which has prominently been formalized in the theory of hierarchical predictive coding (hPC). However, experimental evidence for error units, which are central to the…

Neurons and Cognition · Quantitative Biology 2022-11-23 Fabian A. Mikulasch , Lucas Rudelt , Michael Wibral , Viola Priesemann

Individual differences in human intelligence can be modeled and predicted from in vivo neurobiological connectivity. Many established modeling frameworks for predicting intelligence, however, discard higher-order information about…

Neurons and Cognition · Quantitative Biology 2022-03-07 Evan D. Anderson , Ramsey Wilcox , Anuj Nayak , Christopher Zwilling , Pablo Robles-Granda , Been Kim , Lav R. Varshney , Aron K. Barbey

Connected networks are a fundamental structure of neurobiology. Understanding these networks will help us elucidate the neural mechanisms of computation. Mathematically speaking these networks are `graphs' - structures containing objects…

Neurons and Cognition · Quantitative Biology 2020-10-20 Carl J. Nelson , Stephen Bonner

Currently, connectomes (e.g., functional or structural brain graphs) can be estimated in humans at $\approx 1~mm^3$ scale using a combination of diffusion weighted magnetic resonance imaging, functional magnetic resonance imaging and…

Graphs and hypergraphs are foundational structures in discrete mathematics. They have many practical applications, including the rapidly developing field of bioinformatics, and more generally, biomathematics. They are also a source of…

Combinatorics · Mathematics 2019-01-16 Mark Budden , Josh Hiller , Andrew Penland

Given a social network, which of its nodes are more central? This question has been asked many times in sociology, psychology and computer science, and a whole plethora of centrality measures (a.k.a. centrality indices, or rankings) were…

Data Structures and Algorithms · Computer Science 2013-08-13 Paolo Boldi , Sebastiano Vigna

Data-driven graph learning models a network by determining the strength of connections between its nodes. The data refers to a graph signal which associates a value with each graph node. Existing graph learning methods either use simplified…

Machine Learning · Computer Science 2020-11-05 Nafiseh Ghoroghchian , David M. Groppe , Roman Genov , Taufik A. Valiante , Stark C. Draper

Graph theoretical approach has proved an effective tool to understand, characterize and quantify the complex brain network. However, much less attention has been paid to methods that quantitatively compare two graphs, a crucial issue in the…

Neurons and Cognition · Quantitative Biology 2019-08-29 Ahmad Mheich , Fabrice Wendling , Mahmoud Hassan

Identifying unusual brain activity is a crucial task in neuroscience research, as it aids in the early detection of brain disorders. It is common to represent brain networks as graphs, and researchers have developed various graph-based…

Machine Learning · Computer Science 2024-10-04 Sadaf Sadeghian , Xiaoxiao Li , Margo Seltzer

Gaining insights into the structural and functional mechanisms of the brain has been a longstanding focus in neuroscience research, particularly in the context of understanding and treating neuropsychiatric disorders such as Schizophrenia…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Badhan Mazumder , Lei Wu , Vince D. Calhoun , Dong Hye Ye

A systematic assessment of global neural network connectivity through direct electrophysiological assays has remained technically unfeasible even in dissociated neuronal cultures. We introduce an improved algorithmic approach based on…

Neurons and Cognition · Quantitative Biology 2015-06-03 Olav Stetter , Demian Battaglia , Jordi Soriano , Theo Geisel

For constructing neuronal network models computational neuroscientists have access to wide-ranging anatomical data that nevertheless tend to cover only a fraction of the parameters to be determined. Finding and interpreting the most…

In this paper, we study the entropy of a hard random geometric graph (RGG), a commonly used model for spatial networks, where the connectivity is governed by the distances between the nodes. Formally, given a connection range $r$, a hard…

Information Theory · Computer Science 2026-01-19 Praneeth Kumar Vippathalla , Justin P. Coon , Mihai-Alin Badiu