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Deep learning-based methods are gaining traction in digital pathology, with an increasing number of publications and challenges that aim at easing the work of systematically and exhaustively analyzing tissue slides. These methods often…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ting-An Yen , Hung-Chun Hsu , Pushpak Pati , Maria Gabrani , Antonio Foncubierta-Rodríguez , Pau-Choo Chung

Masked image modelling (MIM) is a powerful self-supervised representation learning paradigm, whose potential has not been widely demonstrated in medical image analysis. In this work, we show the capacity of MIM to capture rich semantic…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Piotr Wójcik , Hussein Naji , Adrian Simon , Reinhard Büttner , Katarzyna Bożek

Melanoma is the most lethal form of skin cancer, with an increasing incidence rate worldwide. Analyzing histological images of melanoma by localizing and classifying tissues and cell nuclei is considered the gold standard method for…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

Digital pathology is one of the most significant developments in modern medicine. Pathological examinations are the gold standard of medical protocols and play a fundamental role in diagnosis. Recently, with the advent of digital scanners,…

Image and Video Processing · Electrical Eng. & Systems 2021-12-09 Mahdi Arab Loodaricheh , Nader Karimi , Shadrokh Samavi

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

Quantitative Methods · Quantitative Biology 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

We present our winning solution to the SIIM-ISIC Melanoma Classification Challenge. It is an ensemble of convolutions neural network (CNN) models with different backbones and input sizes, most of which are image-only models while a few of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-13 Qishen Ha , Bo Liu , Fuxu Liu

The burden of liver tumors is important, ranking as the fourth leading cause of cancer mortality. In case of hepatocellular carcinoma (HCC), the delineation of liver and tumor on contrast-enhanced magnetic resonance imaging (CE-MRI) is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Benjamin Lambert , Pauline Roca , Florence Forbes , Senan Doyle , Michel Dojat

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

The detection of nuclei and cells in histology images is of great value in both clinical practice and pathological studies. However, multiple reasons such as morphological variations of nuclei or cells make it a challenging task where…

Computer Vision and Pattern Recognition · Computer Science 2021-06-28 Yibao Sun , Xingru Huang , Huiyu Zhou , Qianni Zhang

Automatic cell segmentation is an essential step in the pipeline of computer-aided diagnosis (CAD), such as the detection and grading of breast cancer. Accurate segmentation of cells can not only assist the pathologists to make a more…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Muyi Sun , Zeyi Yao , Guanhong Zhang

Colorectal cancer is the third-most common cancer in the Western Hemisphere. The segmentation of colorectal and colorectal cancer by computed tomography is an urgent problem in medicine. Indeed, a system capable of solving this problem will…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 I. M. Chernenkiy , Y. A. Drach , S. R. Mustakimova , V. V. Kazantseva , N. A. Ushakov , S. K. Efetov , M. V. Feldsherov

Nuclei instance segmentation in pathological images is crucial for downstream tasks such as tumor microenvironment analysis. However, the high cost and scarcity of annotated data limit the applicability of fully supervised methods, while…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Zenan Lin , Wei Li , Jintao Chen , Zihao Wu , Wenxiong Kang , Changxin Gao , Liansheng Wang , Jin-Gang Yu

Digital pathology has made significant advances in tumor diagnosis and segmentation, but image variability due to differences in organs, tissue preparation, and acquisition - known as domain shift - limits the effectiveness of current…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Ho Heon Kim , Won Chan Jeong , Young Shin Ko , Young Jin Park

Nuclear segmentation in histology images is a challenging task due to significant variations in the shape and appearance of nuclei. One of the main hurdles in nuclear instance segmentation is overlapping nuclei where a smart algorithm is…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Navid Alemi Koohbanani , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Segmentation and classification of cell nuclei in histopathology images using deep neural networks (DNNs) can save pathologists' time for diagnosing various diseases, including cancers, by automating cell counting and morphometric…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Amruta Parulekar , Utkarsh Kanwat , Ravi Kant Gupta , Medha Chippa , Thomas Jacob , Tripti Bameta , Swapnil Rane , Amit Sethi

Pathological diagnosis is the gold standard for tumor diagnosis, and nucleus instance segmentation is a key step in digital pathology analysis and pathological diagnosis. However, the computational efficiency of the model and the treatment…

Image and Video Processing · Electrical Eng. & Systems 2025-05-09 Shengchun Xiong , Xiangru Li , Yunpeng Zhong , Wanfen Peng

Nuclei instance segmentation in hematoxylin and eosin (H&E)-stained images plays an important role in automated histological image analysis, with various applications in downstream tasks. While several machine learning and deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

Accurate nuclei segmentation in histopathological images is crucial for cancer diagnosis. Automating this process offers valuable support to clinical experts, as manual annotation is time-consuming and prone to human errors. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Ayush Roy , Payel Pramanik , Dmitrii Kaplun , Sergei Antonov , Ram Sarkar

Separating overlapped nuclei is a major challenge in histopathology image analysis. Recently published approaches have achieved promising overall performance on public datasets; however, their performance in segmenting overlapped nuclei are…

Image and Video Processing · Electrical Eng. & Systems 2020-02-05 Haotian Wang , Min Xian , Aleksandar Vakanski

It has been shown that for automated PAP-smear image classification, nucleus features can be very informative. Therefore, the primary step for automated screening can be cell-nuclei detection followed by segmentation of nuclei in the…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Srishti Gautam , Harinarayan K. K. , Nirmal Jith , Anil K. Sao , Arnav Bhavsar , Adarsh Natarajan