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Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Satoshi Kondo , Satoshi Kasai

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Simon Graham , Mostafa Jahanifar , Quoc Dang Vu , Giorgos Hadjigeorghiou , Thomas Leech , David Snead , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Nuclear segmentation and classification within Haematoxylin & Eosin stained histology images is a fundamental prerequisite in the digital pathology work-flow. The development of automated methods for nuclear segmentation and classification…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Simon Graham , Quoc Dang Vu , Shan E Ahmed Raza , Ayesha Azam , Yee Wah Tsang , Jin Tae Kwak , Nasir Rajpoot

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Chunhui Lin , Liukun Zhang , Lijian Mao , Min Wu , Dong Hu

We describe here the panoptic segmentation method we devised for our participation in the CoNIC: Colon Nuclei Identification and Counting Challenge at ISBI 2022. Key features of our method are a weighted loss specifically engineered for…

Image and Video Processing · Electrical Eng. & Systems 2022-04-20 Josef Lorenz Rumberger , Elias Baumann , Peter Hirsch , Andrew Janowczyk , Inti Zlobec , Dagmar Kainmueller

Nuclear segmentation and classification is an essential step for computational pathology. TIA lab from Warwick University organized a nuclear segmentation and classification challenge (CoNIC) for H&E stained histopathology images in…

Image and Video Processing · Electrical Eng. & Systems 2022-03-22 Jijun Cheng , Xipeng Pan , Feihu Hou , Bingchao Zhao , Jiatai Lin , Zhenbing Liu , Zaiyi Liu , Chu Han

Automatic nuclei segmentation and classification play a vital role in digital pathology. However, previous works are mostly built on data with limited diversity and small sizes, making the results questionable or misleading in actual…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Kai Yao , Kaizhu Huang , Jie Sun , Amir Hussain

Simultaneous segmentation and classification of nuclei in digital histology play an essential role in computer-assisted cancer diagnosis; however, it remains challenging. The highest achieved binary and multi-class Panoptic Quality (PQ)…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Ibtihaj Ahmad , Syed Muhammad Israr , Zain Ul Islam

In this work, we tackle the problem of instance segmentation, the task of simultaneously solving object detection and semantic segmentation. Towards this goal, we present a model, called MaskLab, which produces three outputs: box detection,…

Computer Vision and Pattern Recognition · Computer Science 2017-12-14 Liang-Chieh Chen , Alexander Hermans , George Papandreou , Florian Schroff , Peng Wang , Hartwig Adam

Manually annotating nuclei from the gigapixel Hematoxylin and Eosin (H&E)-stained Whole Slide Images (WSIs) is a laborious and costly task, meaning automated algorithms for cell nuclei instance segmentation and classification could…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 João D. Nunes , Diana Montezuma , Domingos Oliveira , Tania Pereira , Jaime S. Cardoso

We demonstrate our solution for the 2019 COCO panoptic segmentation task. Our method first performs instance segmentation and semantic segmentation separately, then combines the two to generate panoptic segmentation results. To enhance the…

Computer Vision and Pattern Recognition · Computer Science 2023-04-21 Mehmet Yildirim , Yogesh Langhe

Identification and quantification of nuclei in colorectal cancer haematoxylin \& eosin (H\&E) stained histology images is crucial to prognosis and patient management. In computational pathology these tasks are referred to as nuclear…

Quantitative Methods · Quantitative Biology 2022-03-08 Muhammad Dawood , Raja Muhammad Saad Bashir , Srijay Deshpande , Manahil Raza , Adam Shephard

Histopathology image analysis is critical yet challenged by the demand of segmenting tissue regions and nuclei instances for tumor microenvironment and cellular morphology analysis. Existing studies focused on tissue semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Qing Xu , Wenting Duan , Zhen Chen

In computational pathology, automatic nuclei instance segmentation plays an essential role in whole slide image analysis. While many computerized approaches have been proposed for this task, supervised deep learning (DL) methods have shown…

Image and Video Processing · Electrical Eng. & Systems 2023-08-04 Amirreza Mahbod , Christine Polak , Katharina Feldmann , Rumsha Khan , Katharina Gelles , Georg Dorffner , Ramona Woitek , Sepideh Hatamikia , Isabella Ellinger

We propose an approach to instance-level image segmentation that is built on top of category-level segmentation. Specifically, for each pixel in a semantic category mask, its corresponding instance bounding box is predicted using a deep…

Computer Vision and Pattern Recognition · Computer Science 2016-05-24 Zifeng Wu , Chunhua Shen , Anton van den Hengel

Nuclei instance segmentation in hematoxylin and eosin (H&E)-stained images plays an important role in automated histological image analysis, with various applications in downstream tasks. While several machine learning and deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

Instance segmentation and classification of nuclei is an important task in computational pathology. We show that StarDist, a deep learning nuclei segmentation method originally developed for fluorescence microscopy, can be extended and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Martin Weigert , Uwe Schmidt

Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Wenhua Zhang , Sen Yang , Meiwei Luo , Chuan He , Yuchen Li , Jun Zhang , Xiyue Wang , Fang Wang

Automated cell nucleus segmentation and classification are required to assist pathologists in their decision making. The Colon Nuclei Identification and Counting Challenge 2022 (CoNIC Challenge 2022) supports the development and…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Moritz Böhland , Oliver Neumann , Marcel P. Schilling , Markus Reischl , Ralf Mikut , Katharina Löffler , Tim Scherr

Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology and patient outcome. To drive innovation in this area, we setup a community-wide challenge using…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Simon Graham , Quoc Dang Vu , Mostafa Jahanifar , Martin Weigert , Uwe Schmidt , Wenhua Zhang , Jun Zhang , Sen Yang , Jinxi Xiang , Xiyue Wang , Josef Lorenz Rumberger , Elias Baumann , Peter Hirsch , Lihao Liu , Chenyang Hong , Angelica I. Aviles-Rivero , Ayushi Jain , Heeyoung Ahn , Yiyu Hong , Hussam Azzuni , Min Xu , Mohammad Yaqub , Marie-Claire Blache , Benoît Piégu , Bertrand Vernay , Tim Scherr , Moritz Böhland , Katharina Löffler , Jiachen Li , Weiqin Ying , Chixin Wang , Dagmar Kainmueller , Carola-Bibiane Schönlieb , Shuolin Liu , Dhairya Talsania , Yughender Meda , Prakash Mishra , Muhammad Ridzuan , Oliver Neumann , Marcel P. Schilling , Markus Reischl , Ralf Mikut , Banban Huang , Hsiang-Chin Chien , Ching-Ping Wang , Chia-Yen Lee , Hong-Kun Lin , Zaiyi Liu , Xipeng Pan , Chu Han , Jijun Cheng , Muhammad Dawood , Srijay Deshpande , Raja Muhammad Saad Bashir , Adam Shephard , Pedro Costa , João D. Nunes , Aurélio Campilho , Jaime S. Cardoso , Hrishikesh P S , Densen Puthussery , Devika R G , Jiji C , Ye Zhang , Zijie Fang , Zhifan Lin , Yongbing Zhang , Chunhui Lin , Liukun Zhang , Lijian Mao , Min Wu , Vi Thi-Tuong Vo , Soo-Hyung Kim , Taebum Lee , Satoshi Kondo , Satoshi Kasai , Pranay Dumbhare , Vedant Phuse , Yash Dubey , Ankush Jamthikar , Trinh Thi Le Vuong , Jin Tae Kwak , Dorsa Ziaei , Hyun Jung , Tianyi Miao , David Snead , Shan E Ahmed Raza , Fayyaz Minhas , Nasir M. Rajpoot
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