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Retinal fundus photography enhancement is important for diagnosing and monitoring retinal diseases. However, early approaches to retinal image enhancement, such as those based on Generative Adversarial Networks (GANs), often struggle to…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Xuanzhao Dong , Wenhui Zhu , Xin Li , Guoxin Sun , Yi Su , Oana M. Dumitrascu , Yalin Wang

This study introduces a groundbreaking optical coherence tomography (OCT) imaging system dedicated for high-throughput screening applications using ex vivo tissue culture. Leveraging OCT's non-invasive, high-resolution capabilities, the…

The highest three-dimensional (3D) resolution possible in in-vivo retinal imaging is achieved by combining optical coherence tomography (OCT) and adaptive optics (AO). However, this combination brings important limitations, such as small…

Medical Physics · Physics 2020-10-21 Jules Scholler , Kassandra Groux , Kate Grieve , Claude Boccara , Pedro Mecê

We propose a template matching method for the detection of 2D image objects that are characterized by orientation patterns. Our method is based on data representations via orientation scores, which are functions on the space of positions…

Computer Vision and Pattern Recognition · Computer Science 2017-03-10 Erik J. Bekkers , Marco Loog , Bart M. ter Haar Romeny , Remco Duits

Modern optical coherence tomography (OCT) devices provide volumetric images with micrometer-scale spatial resolution and a temporal resolution beyond video rate. In this work, we analyze an OCT-based prototypical tracking system which…

Image and Video Processing · Electrical Eng. & Systems 2020-01-22 Matthias Schlüter , Lukas Glandorf , Johanna Sprenger , Martin Gromniak , Maximilian Neidhardt , Thore Saathoff , Alexander Schlaefer

We report, to our knowledge, the first end-to-end application of Generative Adversarial Networks (GANs) towards the synthesis of Optical Coherence Tomography (OCT) images of the retina. Generative models have gained recent attention for the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-19 Stephen G. Odaibo , M. D. , M. S. , M. S.

With the introduction of spectral-domain optical coherence tomography (SDOCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, there is a critical need…

Computer Vision and Pattern Recognition · Computer Science 2015-08-06 Yankui Sun , Tian Zhang , Yue Zhao , Yufan He

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Tracking the pose of instruments is a central problem in image-guided surgery. For microscopic scenarios, optical coherence tomography (OCT) is increasingly used as an imaging modality. OCT is suitable for accurate pose estimation due to…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Nils Gessert , Matthias Schlüter , Alexander Schlaefer

Optical Coherence Tomography (OCT) is an imaging modality that has been widely adopted for visualizing corneal, retinal and limbal tissue structure with micron resolution. It can be used to diagnose pathological conditions of the eye, and…

Image and Video Processing · Electrical Eng. & Systems 2019-05-08 Jiahong Ouyang , Tejas Sudharshan Mathai , Kira Lathrop , John Galeotti

Clinical tracking systems are popular but typically require specific tracking markers. During the last years, scanning speed of optical coherence tomography (OCT) has increased to A-scan rates above 1 MHz allowing to acquire volume scans of…

Medical Physics · Physics 2019-01-15 Matthias Schlüter , Christoph Otte , Thore Saathoff , Nils Gessert , Alexander Schlaefer

Optical Coherence Tomography (OCT) imaging plays an important role in glaucoma diagnosis in clinical practice. Early detection and timely treatment can prevent glaucoma patients from permanent vision loss. However, only a dearth of…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Xi Wang , Hao Chen , Luyang Luo , An-ran Ran , Poemen P. Chan , Clement C. Tham , Carol Y. Cheung , Pheng-Ann Heng

This study is to demonstrate deep learning for automated artery-vein (AV) classification in optical coherence tomography angiography (OCTA). The AV-Net, a fully convolutional network (FCN) based on modified U-shaped CNN architecture,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Minhaj Alam , David Le , Taeyoon Son , Jennifer I. Lim , Xincheng Yao

The utilisation of deep learning segmentation algorithms that learn complex organs and tissue patterns and extract essential regions of interest from the noisy background to improve the visual ability for medical image diagnosis has…

Computer Vision and Pattern Recognition · Computer Science 2023-11-03 Yanming Guo

Glaucoma, a leading cause of irreversible blindness, necessitates early detection for accurate and timely intervention to prevent irreversible vision loss. In this study, we present a novel deep learning framework that leverages the…

Image and Video Processing · Electrical Eng. & Systems 2025-09-05 Mona Ashtari-Majlan , David Masip

The automatic detection and localization of anatomical features in retinal imaging data are relevant for many aspects. In this work, we follow a data-centric approach to optimize classifier training for optic nerve head detection and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Thomas Schlegl , Heiko Stino , Michael Niederleithner , Andreas Pollreisz , Ursula Schmidt-Erfurth , Wolfgang Drexler , Rainer A. Leitgeb , Tilman Schmoll

Optical coherence tomography (OCT) is used for non-invasive diagnosis of diabetic macular edema assessing the retinal layers. In this paper, we propose a new fully convolutional deep architecture, termed ReLayNet, for end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2017-07-10 Abhijit Guha Roy , Sailesh Conjeti , Sri Phani Krishna Karri , Debdoot Sheet , Amin Katouzian , Christian Wachinger , Nassir Navab

We introduce an optimal transport based approach for comparing undirected graphs with non-negative edge weights and general vertex labels, and we study connections between the resulting linear program and the graph isomorphism problem. Our…

Combinatorics · Mathematics 2025-11-20 Phuong N. Hoàng , Kevin McGoff , Andrew B. Nobel , Yang Xiang , Bongsoo Yi

3D to 2D retinal vessel segmentation is a challenging problem in Optical Coherence Tomography Angiography (OCTA) images. Accurate retinal vessel segmentation is important for the diagnosis and prevention of ophthalmic diseases. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-12-17 Zhuojie Wu , Zijian Wang , Wenxuan Zou , Fan Ji , Hao Dang , Wanting Zhou , Muyi Sun

Optimal Transport (OT) has recently emerged as a powerful framework for learning minimal-displacement maps between distributions. The predominant approach involves a neural parametrization of the Monge formulation of OT, typically assuming…

Machine Learning · Computer Science 2024-07-23 Athina Sotiropoulou , David Alvarez-Melis