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Identification and quantification of nuclei in colorectal cancer haematoxylin \& eosin (H\&E) stained histology images is crucial to prognosis and patient management. In computational pathology these tasks are referred to as nuclear…

Quantitative Methods · Quantitative Biology 2022-03-08 Muhammad Dawood , Raja Muhammad Saad Bashir , Srijay Deshpande , Manahil Raza , Adam Shephard

Accurate nuclei segmentation in histopathological images is crucial for cancer diagnosis. Automating this process offers valuable support to clinical experts, as manual annotation is time-consuming and prone to human errors. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Ayush Roy , Payel Pramanik , Dmitrii Kaplun , Sergei Antonov , Ram Sarkar

Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Wenhua Zhang , Sen Yang , Meiwei Luo , Chuan He , Yuchen Li , Jun Zhang , Xiyue Wang , Fang Wang

Computer-aided histopathological image analysis for cancer detection is a major research challenge in the medical domain. Automatic detection and classification of nuclei for cancer diagnosis impose a lot of challenges in developing state…

Computer Vision and Pattern Recognition · Computer Science 2022-02-22 Suvidha Tripathi , Satish Kumar Singh

This short paper reports the algorithms we used and the evaluation performances for ISIC Challenge 2018. Our team participates in all the tasks in this challenge. In lesion segmentation task, the pyramid scene parsing network (PSPNet) is…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Jinyi Zou , Xiao Ma , Cheng Zhong , Yao Zhang

Accurate segmenting nuclei instances is a crucial step in computer-aided image analysis to extract rich features for cellular estimation and following diagnosis as well as treatment. While it still remains challenging because the wide…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Yanning Zhou , Omer Fahri Onder , Qi Dou , Efstratios Tsougenis , Hao Chen , Pheng-Ann Heng

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

Pathological diagnosis is the gold standard for cancer diagnosis, but it is labor-intensive, in which tasks such as cell detection, classification, and counting are particularly prominent. A common solution for automating these tasks is…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Anyu Mao , Jialun Wu , Xinrui Bao , Zeyu Gao , Tieliang Gong , Chen Li

Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Hadar Hezi , Matan Gelber , Alexander Balabanov , Yosef E. Maruvka , Moti Freiman

Automating tissue segmentation and tumor detection in histopathology images of colorectal cancer (CRC) is an enabler for faster diagnostic pathology workflows. At the same time it is a challenging task due to low availability of public…

Image and Video Processing · Electrical Eng. & Systems 2023-04-07 Lydia A. Schoenpflug , Maxime W. Lafarge , Anja L. Frei , Viktor H. Koelzer

Colorectal cancer (CRC) is the third most diagnosed cancer and the second leading cause of cancer-related death worldwide. Accurate histopathological grading of CRC is essential for prognosis and treatment planning but remains a subjective…

We present our winning solution to the SIIM-ISIC Melanoma Classification Challenge. It is an ensemble of convolutions neural network (CNN) models with different backbones and input sizes, most of which are image-only models while a few of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-13 Qishen Ha , Bo Liu , Fuxu Liu

Accurate nuclei segmentation in microscopy whole slide images (WSIs) remains challenging due to variability in staining, imaging conditions, and tissue morphology. We propose CellGenNet, a knowledge distillation framework for robust…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Srijan Ray , Bikesh K. Nirala , Jason T. Yustein , Sundaresh Ram

Automatic cell segmentation is an essential step in the pipeline of computer-aided diagnosis (CAD), such as the detection and grading of breast cancer. Accurate segmentation of cells can not only assist the pathologists to make a more…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Muyi Sun , Zeyi Yao , Guanhong Zhang

Every year millions of people die due to disease of Cancer. Due to its invasive nature it is very complex to cure even in primary stages. Hence, only method to survive this disease completely is via forecasting by analyzing the early…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Shivam Singh , Stuti Pathak

Cell instance segmentation in cytology images has significant importance for biology analysis and cancer screening, while remains challenging due to 1) the extensive overlapping translucent cell clusters that cause the ambiguous boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Hao Jiang , Rushan Zhang , Yanning Zhou , Yumeng Wang , Hao Chen

Sickle cell anemia, which is characterized by abnormal erythrocyte morphology, can be detected using microscopic images. Computational techniques in medicine enhance the diagnosis and treatment efficiency. However, many computational…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Victor Júnio Alcântara Cardoso , Rodrigo Moreira , João Fernando Mari , Larissa Ferreira Rodrigues Moreira

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

Image and Video Processing · Electrical Eng. & Systems 2023-02-10 John-Melle Bokhorst , Iris D. Nagtegaal , Filippo Fraggetta , Simona Vatrano , Wilma Mesker , Michael Vieth , Jeroen van der Laak , Francesco Ciompi

Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

Computer Vision and Pattern Recognition · Computer Science 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

Deep learning has proven to be more effective than other methods in medical image analysis, including the seemingly simple but challenging task of segmenting individual cells, an essential step for many biological studies. Comparative…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Valentina Vadori , Antonella Peruffo , Jean-Marie Graïc , Livio Finos , Livio Corain , Enrico Grisan