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This paper presents a proof-of-concept digital twin framework for simulation-driven diabetes modeling using benchmark clinical data, synthetic temporal augmentation, and illustrative continuous glucose monitoring (CGM) analysis. Unlike…

Machine Learning · Computer Science 2026-05-13 Zarrin Monirzadeh

This paper presents a Nonlinear Model Predictive Control (NMPC) scheme targeted at motion planning for mechatronic motion systems, such as drones and mobile platforms. NMPC-based motion planning typically requires low computation times to…

Robotics · Computer Science 2024-10-28 Dries Dirckx , Mathias Bos , Bastiaan Vandewal , Lander Vanroye , Wilm Decré , Jan Swevers

Describing dynamic medical systems using machine learning is a challenging topic with a wide range of applications. In this work, the possibility of modeling the blood glucose level of diabetic patients purely on the basis of measured data…

Machine Learning · Computer Science 2023-03-10 David Jödicke , Daniel Parra , Gabriel Kronberger , Stephan Winkler

Model predictive control (MPC) has become one of the well-established modern control methods for three-phase inverters with an output LC filter, where a high-quality voltage with low total harmonic distortion (THD) is needed. Although it is…

Systems and Control · Computer Science 2020-04-24 Ihab S. Mohamed , Stefano Rovetta , Ton Duc Do , Tomislav Dragicevic , Ahmed A. Zaki Diab

In the U.S., over a third of adults are pre-diabetic, with 80\% unaware of their status. This underlines the need for better glucose monitoring to prevent type 2 diabetes and related heart diseases. Existing wearable glucose monitors are…

Signal Processing · Electrical Eng. & Systems 2024-06-26 Yidong Zhu , Nadia B Aimandi , Mohammad Arif Ul Alam

The Nearly Autonomous Management and Control System (NAMAC) is a comprehensive control system that assists plant operations by furnishing control recommendations to operators in a broad class of situations. This study refines a NAMAC system…

Artificial Intelligence · Computer Science 2021-05-25 Linyu Lin , Paridhi Athe , Pascal Rouxelin , Maria Avramova , Abhinav Gupta , Robert Youngblood , Nam Dinh

To match the growing demand for bio-methane production, anaerobic digesters need to embrace the co-digestion of different feedstocks; in addition, to improve the techno-economic performance, an optimal and time-varying adaptation of the…

Systems and Control · Electrical Eng. & Systems 2026-01-06 Davide Carecci , Laurent Dewasme , Alessio La Bella , Gianni Ferretti , Alain Vande Wouwer

Nonlinear Model Predictive Control (NMPC) offers a powerful approach for controlling complex nonlinear systems, yet faces two key challenges. First, accurately modeling nonlinear dynamics remains difficult. Second, variables directly…

Systems and Control · Electrical Eng. & Systems 2026-02-03 Kosei Tsuji , Ichiro Maruta , Kenji Fujimoto , Tomoyuki Maeda , Yoshihisa Tamase , Tsukasa Shinohara

Nonlinear Model Predictive Control (NMPC) is a powerful and widely used technique for nonlinear dynamic process control under constraints. In NMPC, the state and control weights of the corresponding state and control costs are commonly…

Optimization and Control · Mathematics 2020-08-07 Dimche Kostadinov , Davide Scaramuzza

Medical drug infusion problems pose a combination of challenges such as nonlinearities from physiological models, model uncertainty due to inter- and intra-patient variability, as well as strict safety specifications. With these challenges…

Systems and Control · Electrical Eng. & Systems 2023-01-24 Sophie Hall , Lukas Ortmann , Miguel Picallo , Florian Dörfler

We compare the performance of proportional-integral-derivative (PID) control, linear model predictive control (LMPC), and nonlinear model predictive control (NMPC) for a physical setup of the quadruple tank system (QTS). We estimate the…

Systems and Control · Electrical Eng. & Systems 2022-12-12 Anders H. D. Andersen , Tobias K. S. Ritschel , Steen Hørsholt , Jakob Kjøbsted Huusom , John Bagterp Jørgensen

We present a versatile nonlinear model predictive control (NMPC) formulation for quadrupedal locomotion. Our formulation jointly optimizes a base trajectory and a set of footholds over a finite time horizon based on simplified dynamics…

Robotics · Computer Science 2022-07-22 Dongho Kang , Flavio De Vincenti , Stelian Coros

Precise glucose level monitoring is critical for people with diabetes to avoid serious complications. While there are several methods for continuous glucose level monitoring, research on maintenance devices is limited. To mitigate the gap,…

Machine Learning · Computer Science 2024-06-10 Azmine Toushik Wasi

Artificial neural networks (ANN) have been shown to be flexible and effective function estimators for identification of nonlinear state-space models. However, if the resulting models are used directly for nonlinear model predictive control…

Systems and Control · Electrical Eng. & Systems 2023-04-03 Jan H. Hoekstra , Bence Cseppentő , Gerben I. Beintema , Maarten Schoukens , Zsolt Kollár , Roland Tóth

Model predictive control (MPC) anticipates future events to take appropriate control actions. Nonlinear MPC (NMPC) describes systems with nonlinear models and/or constraints. A Continuation/GMRES Method for NMPC, suggested by T. Ohtsuka in…

Optimization and Control · Mathematics 2015-09-10 Andrew Knyazev , Yuta Fujii , Alexander Malyshev

A dual adaptive model predictive control (MPC) algorithm is presented for linear, time-invariant systems subject to bounded disturbances and parametric uncertainty in the state-space matrices. Online set-membership identification is…

Systems and Control · Electrical Eng. & Systems 2021-02-23 Anilkumar Parsi , Andrea Iannelli , Roy S. Smith

In this paper, a novel robust tracking control scheme for a general class of discrete-time nonlinear systems affected by unknown bounded uncertainty is presented. By solving a parameterized optimal tracking control problem subject to the…

Systems and Control · Electrical Eng. & Systems 2023-12-08 Alexandros Tanzanakis , John Lygeros

Automating complex industrial robots requires precise nonlinear control and efficient energy management. This paper introduces a data-driven nonlinear model predictive control (NMPC) framework to optimize control under multiple objectives.…

Robotics · Computer Science 2024-11-22 Dexian Ma , Bo Zhou

A task of vital clinical importance, within Diabetes management, is the prevention of hypo/hyperglycemic events. Increasingly adopted Continuous Glucose Monitoring (CGM) devices offer detailed, non-intrusive and real time insights into a…

Machine Learning · Computer Science 2023-03-09 Jakub J. Dylag

Self-monitoring of blood glucose (SMBG) and continuous glucose monitoring (CGM) are commonly used by type 1 diabetes (T1D) patients to measure glucose concentrations. The proposed adaptive basal-bolus algorithm (ABBA) supports inputs from…

Systems and Control · Electrical Eng. & Systems 2024-12-20 Qingnan Sun , Marko V. Jankovic , João Budzinski , Brett Moore , Peter Diem , Christoph Stettler , Stavroula G. Mougiakakou