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Data imbalance remains one of the open challenges in the contemporary machine learning. It is especially prevalent in case of medical data, such as histopathological images. Traditional data-level approaches for dealing with data imbalance…

Machine Learning · Computer Science 2021-04-20 Michał Koziarski

Mitotic counting is a vital prognostic marker of tumor proliferation in breast cancer. Deep learning-based mitotic detection is on par with pathologists, but it requires large labeled data for training. We propose a deep classification…

Computer Vision and Pattern Recognition · Computer Science 2020-07-03 Pushpak Pati , Antonio Foncubierta-Rodriguez , Orcun Goksel , Maria Gabrani

Manual count of mitotic figures, which is determined in the tumor region with the highest mitotic activity, is a key parameter of most tumor grading schemes. It can be, however, strongly dependent on the area selection due to uneven mitotic…

Point cloud upsampling focuses on generating a dense, uniform and proximity-to-surface point set. Most previous approaches accomplish these objectives by carefully designing a single-stage network, which makes it still challenging to…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Hang Du , Xuejun Yan , Jingjing Wang , Di Xie , Shiliang Pu

Pathological diagnosis is the gold standard for cancer diagnosis, but it is labor-intensive, in which tasks such as cell detection, classification, and counting are particularly prominent. A common solution for automating these tasks is…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Anyu Mao , Jialun Wu , Xinrui Bao , Zeyu Gao , Tieliang Gong , Chen Li

Quality control (QC) of MR images is essential to ensure that downstream analyses such as segmentation can be performed successfully. Currently, QC is predominantly performed visually and subjectively, at significant time and operator cost.…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Richard Shaw , Carole H. Sudre , Sebastien Ourselin , M. Jorge Cardoso , Hugh G. Pemberton

Optical transmission spectroscopy is one method to understand brain tissue structural properties from brain tissue biopsy samples, yet manual interpretation is resource intensive and prone to inter observer variability. Deep convolutional…

Medical Physics · Physics 2025-05-20 Mohnish Sao , Mousa Alrubayan , Prabhakar Pradhan

The rapid advancement of deep learning in medical image analysis has greatly enhanced the accuracy of skin cancer classification. However, current state-of-the-art models, especially those based on transfer learning like ResNet50, come with…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Abdullah Al Mamun , Pollob Chandra Ray , Md Rahat Ul Nasib , Akash Das , Jia Uddin , Md Nurul Absur

In recent years, intravital skin imaging has been increasingly used in mammalian skin research to investigate cell behaviors. A fundamental step of the investigation is mitotic cell (cell division) detection. Because of the complex…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Titinunt Kitrungrotsakul , Xian-Hau Han , Yutaro Iwamoto , Satoko Takemoto , Hideo Yokota , Sari Ipponjima , Tomomi Nemoto , Xiong Wei , Yen-Wei Chen

Accurately and quickly binuclear cell (BC) detection plays a significant role in predicting the risk of leukemia and other malignant tumors. However, manual microscopy counting is time-consuming and lacks objectivity. Moreover, with the…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Baomin Wang , Geng Hu , Dan Chen , Lihua Hu , Cheng Li , Yu An , Guiping Hu , Guang Jia

This is the submission for mitosis detection in the context of the MIDOG 2021 challenge. It is based on the two-stage objection model Faster RCNN as well as DenseNet as a backbone for the neural network architecture. It achieves a F1-score…

Computer Vision and Pattern Recognition · Computer Science 2021-09-03 Michel Halmes , Hippolyte Heuberger , Sylvain Berlemont

Residual networks (ResNets) represent a powerful type of convolutional neural network (CNN) architecture, widely adopted and used in various tasks. In this work we propose an improved version of ResNets. Our proposed improvements address…

Computer Vision and Pattern Recognition · Computer Science 2020-04-13 Ionut Cosmin Duta , Li Liu , Fan Zhu , Ling Shao

In-vivo optical microscopy is advancing into routine clinical practice for non-invasively guiding diagnosis and treatment of cancer and other diseases, and thus beginning to reduce the need for traditional biopsy. However, reading and…

Image and Video Processing · Electrical Eng. & Systems 2020-01-07 Kivanc Kose , Alican Bozkurt , Christi Alessi-Fox , Melissa Gill , Caterina Longo , Giovanni Pellacani , Jennifer Dy , Dana H. Brooks , Milind Rajadhyaksha

Circulating Tumor Cells (CTCs) bear great promise as biomarkers in tumor prognosis. However, the process of identification and later enumeration of CTCs require manual labor, which is error-prone and time-consuming. The recent developments…

Computer Vision and Pattern Recognition · Computer Science 2022-08-08 Elena Alexander , Kam W. Leong , Andrew F. Laine

We consider an MRI reconstruction problem with input of k-space data at a very low undersampled rate. This can practically benefit patient due to reduced time of MRI scan, but it is also challenging since quality of reconstruction may be…

Computer Vision and Pattern Recognition · Computer Science 2019-04-11 Qiaoying Huang , Dong Yang , Pengxiang Wu , Hui Qu , Jingru Yi , Dimitris Metaxas

Studies estimate that there will be 266,120 new cases of invasive breast cancer and 40,920 breast cancer induced deaths in the year of 2018 alone. Despite the pervasiveness of this affliction, the current process to obtain an accurate…

Computer Vision and Pattern Recognition · Computer Science 2018-07-06 Siddhant Rao

A ResNet-based multi-path refinement CNN is used for object contour detection. For this task, we prioritise the effective utilization of the high-level abstraction capability of a ResNet, which leads to state-of-the-art results for edge…

Computer Vision and Pattern Recognition · Computer Science 2019-08-26 Andre Peter Kelm , Vijesh Soorya Rao , Udo Zoelzer

Automated breast cancer detection via computer vision techniques is challenging due to the complex nature of breast tissue, the subtle appearance of cancerous lesions, and variations in breast density. Mainstream techniques primarily focus…

Quantitative Methods · Quantitative Biology 2025-12-11 Noor Ul Huda Shah , Tanveer Hussain , Amr Ahmed , Yonghuai Liu , Usman Ali , Ardhendu Behera

Accurate, automated lesion detection in Computed Tomography (CT) is an important yet challenging task due to the large variation of lesion types, sizes, locations and appearances. Recent work on CT lesion detection employs two-stage region…

Image and Video Processing · Electrical Eng. & Systems 2019-06-07 Martin Zlocha , Qi Dou , Ben Glocker

Mitotic activity is a crucial proliferation biomarker for the diagnosis and prognosis of different types of cancers. Nevertheless, mitosis counting is a cumbersome process for pathologists, prone to low reproducibility, due to the large…

Image and Video Processing · Electrical Eng. & Systems 2022-12-01 Claudio Fernandez-Martín , Umay Kiraz , Julio Silva-Rodríguez , Sandra Morales , Emiel Janssen , Valery Naranjo