Related papers: RestainNet: a self-supervised digital re-stainer f…
Histopathology relies on the analysis of microscopic tissue images to diagnose disease. A crucial part of tissue preparation is staining whereby a dye is used to make the salient tissue components more distinguishable. However, differences…
The different stain styles of cytopathological images have a negative effect on the generalization ability of automated image analysis algorithms. This article proposes a new framework that normalizes the stain style for cytopathological…
Staining is critical to cell imaging and medical diagnosis, which is expensive, time-consuming, labor-intensive, and causes irreversible changes to cell tissues. Recent advances in deep learning enabled digital staining via supervised model…
The diagnosis of cancer is mainly performed by visual analysis of the pathologists, through examining the morphology of the tissue slices and the spatial arrangement of the cells. If the microscopic image of a specimen is not stained, it…
In this paper, we develop a complete pipeline for stain normalization, segmentation, and classification of nuclei in hematoxylin and eosin (H&E) stained breast cancer histopathology images. In the first step, we use a CNN-based stain…
Hematoxylin and Eosin (H&E) has been the gold standard in tissue analysis for decades, however, tissue specimens stained in different laboratories vary, often significantly, in appearance. This variation poses a challenge for both…
The rapid growth of digital pathology in recent years has provided an ideal opportunity for the development of artificial intelligence-based tools to improve the accuracy and efficiency of clinical diagnoses. One of the significant…
Although generative adversarial network (GAN) based style transfer is state of the art in histopathology color-stain normalization, they do not explicitly integrate structural information of tissues. We propose a self-supervised approach to…
Virtual immunohistochemistry (IHC) staining from hematoxylin and eosin (H&E) images can accelerate diagnostics by providing preliminary molecular insight directly from routine sections, reducing the need for repeat sectioning when tissue is…
Virtual stain transfer is a promising area of research in Computational Pathology, which has a great potential to alleviate important limitations when applying deeplearningbased solutions such as lack of annotations and sensitivity to a…
Variability in staining protocols, such as different slide preparation techniques, chemicals, and scanner configurations, can result in a diverse set of whole slide images (WSIs). This distribution shift can negatively impact the…
Image colorization is the process of colorizing grayscale images or recoloring an already-color image. This image manipulation can be used for grayscale satellite, medical and historical images making them more expressive. With the help of…
Enhancing the generalization capability of deep neural networks to unseen domains is crucial for safety-critical applications in the real world such as autonomous driving. To address this issue, this paper proposes a novel instance…
We propose a novel Retinex image-decomposition network that can be trained in a self-supervised manner. The Retinex image-decomposition aims to decompose an image into illumination-invariant and illumination-variant components, referred to…
Color constancy aims to restore the constant colors of a scene under different illuminants. However, due to the existence of camera spectral sensitivity, the network trained on a certain sensor, cannot work well on others. Also, since the…
Computational histopathology image diagnosis becomes increasingly popular and important, where images are segmented or classified for disease diagnosis by computers. While pathologists do not struggle with color variations in slides,…
For many practical computer vision applications, the learned models usually have high performance on the datasets used for training but suffer from significant performance degradation when deployed in new environments, where there are…
Learning-based methods have demonstrated remarkable performance in solving inverse problems, particularly in image reconstruction tasks. Despite their success, these approaches often lack theoretical guarantees, which are crucial in…
Accurate gland segmentation in histopathology images is essential for cancer diagnosis and prognosis. However, significant variability in Hematoxylin and Eosin (H&E) staining and tissue morphology, combined with limited annotated data,…
Convolutional Neural Networks (CNNs) for visual tasks are believed to learn both the low-level textures and high-level object attributes, throughout the network depth. This paper further investigates the `texture bias' in CNNs. To this end,…