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Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for early diagnosis of retinal diseases. In…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Peyman Gholami , Priyanka Roy , Mohana Kuppuswamy Parthasarathy , Vasudevan Lakshminarayanan

This letter is the first to report that a super-resolution imaging beyond the Rayleigh limit can be achieved by using classical diffraction tomography (DT) extended with orbital angular momentum (OAM), termed as OAM based diffraction…

Optics · Physics 2015-06-16 Lianlin Li , Fang Li

The approach to obtain the image shape of an optical diffraction radiation (ODR) source focused by lens on a detector with taking into account the "pre-wave zone" effect has been developed. In full analogy with optical transition radiation…

Accelerator Physics · Physics 2007-05-23 A. P. Potylitsyn

Fluorescence microscopy is a powerful tool for imaging biological samples with molecular specificity. In contrast, phase microscopy provides label-free measurement of the sample's refractive index (RI), which is an intrinsic optical…

Optics · Physics 2022-01-26 Yi Xue , David Ren , Laura Waller

Optical Coherence Tomography (OCT) is one of the most emerging imaging modalities that has been used widely in the field of biomedical imaging. From its emergence in 1990's, plenty of hardware and software improvements have been made. Its…

Computer Vision and Pattern Recognition · Computer Science 2014-11-18 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

In this paper, we study the mathematical imaging problem of optical diffraction tomography (ODT) for the scenario of a microscopic rigid particle rotating in a trap created, for instance, by acoustic or optical forces. Under the influence…

Spatial resolution in optical microscopy has traditionally been treated as a fixed parameter of the optical system. Here, we present an approach to enhance transverse resolution in beam-scanned optical coherence tomography (OCT) beyond its…

Optics · Physics 2021-10-22 Nichaluk Leartprapun , Steven G. Adie

The highest three-dimensional (3D) resolution possible in in-vivo retinal imaging is achieved by combining optical coherence tomography (OCT) and adaptive optics (AO). However, this combination brings important limitations, such as small…

Medical Physics · Physics 2020-10-21 Jules Scholler , Kassandra Groux , Kate Grieve , Claude Boccara , Pedro Mecê

Diffraction tomography is a widely used inverse scattering technique for quantitative imaging of weakly scattering media. In its conventional formulation, diffraction tomography assumes monochromatic plane wave illumination. This…

Numerical Analysis · Mathematics 2026-03-11 Peter Elbau , Noemi Naujoks , Otmar Scherzer

Optical coherence Doppler tomography (ODT) is an emerging blood flow imaging technique. The fundamental unit of ODT is the 1D depth-resolved trace named raw A-scans (or A-line). A 2D ODT image (B-scan) is formed by reconstructing a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Zhenghong Li , Jiaxiang Ren , Wensheng Cheng , Yanzuo Liu , Congwu Du , Yingtian Pan , Haibin Ling

Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep…

Optical Coherence Tomography (OCT) was originally conceived as a volumetric imaging method. Quickly, OCT images went beyond structural data and started to provide functional information about an object enabling for example visualization of…

Knowledge of optical properties, such as the refractive index (RI), of biological tissues is important in optical imaging, as they influence the distribution and propagation of light in tissue. To accurately study the response of cancerous…

Biological Physics · Physics 2019-04-10 Neelam Hari , Priyanka Patel , Jacqueline Ross , Kevin Hicks , Frédérique Vanholsbeeck

Many naturally-occuring models in the sciences are well-approximated by simplified models, using multiscale techniques. In such settings it is natural to ask about the relationship between inverse problems defined by the original problem…

Numerical Analysis · Mathematics 2019-02-28 Kit Newton , Qin Li , Andrew Stuart

Quantitative tissue information, like the light scattering properties, is considered as a key player in the detection of cancerous cells in medical diagnosis. A promising method to obtain these data is optical coherence tomography (OCT). In…

Numerical Analysis · Mathematics 2023-06-21 Leopold Veselka , Peter Elbau , Leonidas Mindrinos , Lisa Krainz , Wolfgang Drexler

The evaluation and monitoring of cells health in the human retina is crucial and follow time course of retinal diseases, detect lesions before irreversible visual loss and to evaluate treatment effects. Towards this goal, a major challenge…

Optical Coherence Tomography(OCT) is a non-invasive technique capturing cross-sectional area of the retina in micro-meter resolutions. It has been widely used as a auxiliary imaging reference to detect eye-related pathology and predict…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Shuo Chen , Da Ma , Sieun Lee , Timothy T. L. Yu , Gavin Xu , Donghuan Lu , Karteek Popuri , Myeong Jin Ju , Marinko V. Sarunic , Mirza Faisal Beg

We propose a new technique, called quantum optical coherence tomography (QOCT), for carrying out tomographic measurements with dispersion-cancelled resolution. The technique can also be used to extract the frequency-dependent refractive…

X-ray diffraction tomography (XDT) resolves spatially-variant XRD profiles within macroscopic objects, and provides improved material contrast compared to the conventional transmission-based computed tomography (CT). However, due to the…

Medical Physics · Physics 2019-01-04 Zheyuan Zhu , Alexander Katsevich , Shuo Pang

Optical coherence tomography (OCT) is a prevalent non-invasive imaging method which provides high resolution volumetric visualization of retina. However, its inherent defect, the speckle noise, can seriously deteriorate the tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Dewei Hu , Yuankai K. Tao , Ipek Oguz
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