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Adoption of machine learning models in healthcare requires end users' trust in the system. Models that provide additional supportive evidence for their predictions promise to facilitate adoption. We define consistent evidence to be both…

Computer Vision and Pattern Recognition · Computer Science 2021-11-16 Peiqi Wang , Ruizhi Liao , Daniel Moyer , Seth Berkowitz , Steven Horng , Polina Golland

Detecting anomalies in musculoskeletal radiographs is of paramount importance for large-scale screening in the radiology workflow. Supervised deep networks take for granted a large number of annotations by radiologists, which is often…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Antoine Spahr , Behzad Bozorgtabar , Jean-Philippe Thiran

Explainability is a longstanding challenge in deep learning, especially in high-stakes domains like healthcare. Common explainability methods highlight image regions that drive an AI model's decision. Humans, however, heavily rely on…

Artificial Intelligence · Computer Science 2023-11-21 Shobhit Agarwal , Yevgeniy R. Semenov , William Lotter

We introduce Matched Machine Learning, a framework that combines the flexibility of machine learning black boxes with the interpretability of matching, a longstanding tool in observational causal inference. Interpretability is paramount in…

Methodology · Statistics 2023-04-05 Marco Morucci , Cynthia Rudin , Alexander Volfovsky

Prostate cancer is among the most common cancer in males and its heterogeneity is well known. Its early detection helps making therapeutic decision. There is no standard technique or procedure yet which is full-proof in predicting cancer…

Machine Learning · Computer Science 2018-12-18 Khalid Raza , Atif N Hasan

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

Computation and Language · Computer Science 2025-04-02 Birger Moell , Fredrik Sand Aronsson , Sanian Akbar

Digital mammography is essential to breast cancer detection, and deep learning offers promising tools for faster and more accurate mammogram analysis. In radiology and other high-stakes environments, uninterpretable ("black box") deep…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Julia Yang , Alina Jade Barnett , Jon Donnelly , Satvik Kishore , Jerry Fang , Fides Regina Schwartz , Chaofan Chen , Joseph Y. Lo , Cynthia Rudin

High predictive performance and ease of use and interpretability are important requirements for the applicability of a computer-aided diagnosis (CAD) to human reading studies. We propose a CAD system specifically designed to be more…

Machine Learning · Statistics 2016-06-28 Cristina Gallego-Ortiz , Anne L. Martel

Purpose: Subarachnoid haemorrhage is a potentially fatal consequence of intracranial aneurysm rupture, however, it is difficult to predict if aneurysms will rupture. Prophylactic treatment of an intracranial aneurysm also involves risk,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Karan Daga , Siddharth Agarwal , Zaeem Moti , Matthew BK Lee , Munaib Din , David Wood , Marc Modat , Thomas C Booth

We propose DeepMiner, a framework to discover interpretable representations in deep neural networks and to build explanations for medical predictions. By probing convolutional neural networks (CNNs) trained to classify cancer in mammograms,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Jimmy Wu , Bolei Zhou , Diondra Peck , Scott Hsieh , Vandana Dialani , Lester Mackey , Genevieve Patterson

Automatic report generation has arisen as a significant research area in computer-aided diagnosis, aiming to alleviate the burden on clinicians by generating reports automatically based on medical images. In this work, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Jun Li , Tongkun Su , Baoliang Zhao , Faqin Lv , Qiong Wang , Nassir Navab , Ying Hu , Zhongliang Jiang

Small Language Models (SLMs) have shown remarkable performance in general domain language understanding, reasoning and coding tasks, but their capabilities in the medical domain, particularly concerning radiology text, is less explored. In…

Computation and Language · Computer Science 2024-03-18 Mercy Ranjit , Gopinath Ganapathy , Shaury Srivastav , Tanuja Ganu , Srujana Oruganti

Over the years, there has been growing interest in using Machine Learning techniques for biomedical data processing. When tackling these tasks, one needs to bear in mind that biomedical data depends on a variety of characteristics, such as…

Machine Learning · Computer Science 2020-02-05 Elisa Ferrari , Alessandra Retico , Davide Bacciu

We present Manifold Alignment Determination (MAD), an algorithm for learning alignments between data points from multiple views or modalities. The approach is capable of learning correspondences between views as well as correspondences…

Machine Learning · Statistics 2017-01-13 Andreas Damianou , Neil D. Lawrence , Carl Henrik Ek

The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods. In this paper, we propose MDNet to establish a direct multimodal…

Computer Vision and Pattern Recognition · Computer Science 2017-07-11 Zizhao Zhang , Yuanpu Xie , Fuyong Xing , Mason McGough , Lin Yang

Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…

Computer Vision and Pattern Recognition · Computer Science 2019-03-13 Wentao Zhu

In diagnostic reports, experts encode complex imaging data into clinically actionable information. They describe subtle pathological findings that are meaningful in their anatomical context. Reports follow relatively consistent structures,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Felicia Bader , Philipp Seeböck , Anastasia Bartashova , Ulrike Attenberger , Georg Langs

Safe deployment of deep learning systems in critical real world applications requires models to make very few mistakes, and only under predictable circumstances. In this work, we address this problem using an abstaining classifier that is…

Objective: Breast cancer screening is of great significance in contemporary women's health prevention. The existing machines embedded in the AI system do not reach the accuracy that clinicians hope. How to make intelligent systems more…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Jian Dai , Shuge Lei , Licong Dong , Xiaona Lin , Huabin Zhang , Desheng Sun , Kehong Yuan

Objective: To develop an automatic image normalization algorithm for intensity correction of images from breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) acquired by different MRI scanners with various imaging…

Computer Vision and Pattern Recognition · Computer Science 2018-07-09 Jun Zhang , Ashirbani Saha , Brian J. Soher , Maciej A. Mazurowski