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This work studies the design of safe control policies for large-scale non-linear systems operating in uncertain environments. In such a case, the robust control framework is a principled approach to safety that aims to maximize the…

Systems and Control · Computer Science 2019-03-04 Edouard Leurent , Yann Blanco , Denis Efimov , Odalric-Ambrym Maillard

This paper proposes a robust control design method using reinforcement-learning for controlling partially-unknown dynamical systems under uncertain conditions. The method extends the optimal reinforcement-learning algorithm with a new…

Systems and Control · Electrical Eng. & Systems 2020-04-17 Phuong D. Ngo , Fred Godtliebsen

Empirical evidence has revealed that biological regulatory systems are controlled by high-level coordination between topology and Boolean rules. In this study, we study the joint effects of degree and Boolean functions on the stability of…

Adaptation and Self-Organizing Systems · Physics 2021-03-12 Byungjoon Min

A Boolean network (BN) with $n$ components is a discrete dynamical system described by the successive iterations of a function $f:\{0,1\}^n \to \{0,1\}^n$. This model finds applications in biology, where fixed points play a central role.…

Combinatorics · Mathematics 2022-02-10 Florian Bridoux , Amélia Durbec , Kévin Perrot , Adrien Richard

We present an algorithm for robust model predictive control with consideration of uncertainty and safety constraints. Our framework considers a nonlinear dynamical system subject to disturbances from an unknown but bounded uncertainty set.…

Optimization and Control · Mathematics 2021-04-23 Dongchan Lee , Konstantin Turitsyn , Jean-Jacques Slotine

Biological networks such as gene regulatory networks possess desirable properties. They are more robust and controllable than random networks. This motivates the search for structural and dynamical features that evolution has incorporated…

Molecular Networks · Quantitative Biology 2024-02-16 Claus Kadelka , David Murrugarra

Since their introduction, Boolean networks have been traditionally studied in view of their rich dynamical behavior under different update protocols and for their qualitative analogy with cell regulatory networks. More recently, tools…

Disordered Systems and Neural Networks · Physics 2007-05-23 Michele Leone , Andrea Pagnani , Giorgio Parisi , Osvaldo Zagordi

This paper presents the foundation for a decomposition theory for Boolean networks, a type of discrete dynamical system that has found a wide range of applications in the life sciences, engineering, and physics. Given a Boolean network…

Dynamical Systems · Mathematics 2022-06-10 Claus Kadelka , Reinhard Laubenbacher , David Murrugarra , Alan Veliz-Cuba , Matthew Wheeler

Graph Neural Networks (GNNs) have become widely-used models for semi-supervised learning. However, the robustness of GNNs in the presence of label noise remains a largely under-explored problem. In this paper, we consider an important yet…

Machine Learning · Computer Science 2023-02-28 Siyi Qian , Haochao Ying , Renjun Hu , Jingbo Zhou , Jintai Chen , Danny Z. Chen , Jian Wu

We have considered a Boolean control network where the state evolution equations depend on past states, controls and first derivatives of a function with respect to controls. Total approach has been the efficient use of matrix semi tensor…

Optimization and Control · Mathematics 2020-08-20 Souma Mazumdar

This paper studies the minimum control node set problem for Boolean networks (BNs) with degree constraints. The main contribution is to derive the nontrivial lower and upper bounds on the size of the minimum control node set through…

Systems and Control · Electrical Eng. & Systems 2026-03-03 Liangjie Sun , Wai-Ki Ching , Tatsuya Akutsu

The study of network structural controllability focuses on the minimum number of driver nodes needed to control a whole network. Despite intensive studies on this topic, most of them consider static networks only. It is well-known, however,…

Physics and Society · Physics 2021-01-27 Rui Zhang , Xiaomeng Wang , Ming Cheng , Tao Jia

We consider the problem of stabilization of a linear system, under state and control constraints, and subject to bounded disturbances and unknown parameters in the state matrix. First, using a simple least square solution and available…

Systems and Control · Electrical Eng. & Systems 2020-07-22 Edouard Leurent , Denis Efimov , Odalric-Ambrym Maillard

We investigated the properties of Boolean networks that follow a given reliable trajectory in state space. A reliable trajectory is defined as a sequence of states which is independent of the order in which the nodes are updated. We…

Biological Physics · Physics 2011-03-23 Tiago P. Peixoto , Barbara Drossel

The goal of this tutorial is to promote interest in the study of random Boolean networks (RBNs). These can be very interesting models, since one does not have to assume any functionality or particular connectivity of the networks to study…

Adaptation and Self-Organizing Systems · Physics 2009-09-29 Carlos Gershenson

We will present a new general framework for robust and adaptive control that allows for distributed and scalable learning and control of large systems of interconnected linear subsystems. The control method is demonstrated for a linear…

Systems and Control · Computer Science 2019-04-02 Dimitar Ho , John C. Doyle

Neural networks are vulnerable to adversarial attacks, i.e., small input perturbations can significantly affect the outputs of a neural network. Therefore, to ensure safety of neural networks in safety-critical environments, the robustness…

Machine Learning · Computer Science 2025-08-06 Lukas Koller , Tobias Ladner , Matthias Althoff

Reinforcement learning is a general methodology of adaptive optimal control that has attracted much attention in various fields ranging from video game industry to robot manipulators. Despite its remarkable performance demonstrations, plain…

Dynamical Systems · Mathematics 2022-06-14 Pavel Osinenko , Grigory Yaremenko , Ilya Osokin

In this work we challenge the main conclusions of Gu et al work (Controllability of structural brain networks. Nature communications 6, 8414, doi:10.1038/ncomms9414, 2015) on brain controllability. Using the same methods and analyses on…

Neurons and Cognition · Quantitative Biology 2018-07-10 Chengyi Tu , Rodrigo P. Rocha , Maurizio Corbetta , Sandro Zampieri , Marzo Zorzi , Samir Suweis

Distributionally robust control is a well-studied framework for optimal decision making under uncertainty, with the objective of minimizing an expected cost function over control actions, assuming the most adverse probability distribution…

Systems and Control · Electrical Eng. & Systems 2025-08-12 Alexandros E. Tzikas , Lukas Fiechtner , Arec Jamgochian , Mykel J. Kochenderfer