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The paper addresses challenges in storing and retrieving sequences in contexts like anomaly detection, behavior prediction, and genetic information analysis. Associative Knowledge Graphs (AKGs) offer a promising approach by leveraging…

Artificial Intelligence · Computer Science 2025-09-11 Przemysław Stokłosa , Janusz A. Starzyk , Paweł Raif , Adrian Horzyk , Marcin Kowalik

As machine learning tasks continue to evolve, the trend has been to gather larger datasets and train increasingly larger models. While this has led to advancements in accuracy, it has also escalated computational costs to unsustainable…

Machine Learning · Computer Science 2024-06-03 Mohammad Jafari , Yimeng Zhang , Yihua Zhang , Sijia Liu

Least squares trees, multi-dimensional scaling and Neighbor Nets are all different and popular ways of visualizing multi-dimensional data. The method of flexi-Weighted Least Squares (fWLS) is a powerful method of fitting phylogenetic trees,…

Populations and Evolution · Quantitative Biology 2010-12-30 Peter J. Waddell , Ishita Khan , Xi Tan , Sunghwan Yoo

We have developed an alignment-free method that calculates phylogenetic distances using a maximum likelihood approach for a model of sequence change on patterns that are discovered in unaligned sequences. To evaluate the phylogenetic…

Quantitative Methods · Quantitative Biology 2007-05-23 Michael Höhl , Isidore Rigoutsos , Mark A. Ragan

In systems biology, it is becoming increasingly common to measure biochemical entities at different levels of the same biological system. Hence, data fusion problems are abundant in the life sciences. With the availability of a multitude of…

In this article the results of Waddell and Azad (2009) are extended. In particular, the geometric percentage mean standard deviation measure of the fit of distances to a phylogenetic tree is adjusted for the number of parameters fitted to…

Populations and Evolution · Quantitative Biology 2011-01-04 Peter J. Waddell , Ariful Azad , Ishita Khan

Post-training quantization (PTQ) has emerged as a practical approach to compress large neural networks, making them highly efficient for deployment. However, effectively reducing these models to their low-bit counterparts without…

Machine Learning · Computer Science 2024-10-22 Aozhong Zhang , Zi Yang , Naigang Wang , Yingyong Qi , Jack Xin , Xin Li , Penghang Yin

Gaussian processes offers a convenient way to perform nonparametric reconstructions of observational data assuming only a kernel which describes the covariance between neighbouring points in a data set. We approach the ambiguity in the…

Cosmology and Nongalactic Astrophysics · Physics 2021-08-17 Reginald Christian Bernardo , Jackson Levi Said

The organization of latent token representations plays a crucial role in determining the stability, generalization, and contextual consistency of language models, yet conventional approaches to embedding refinement often rely on parameter…

Computation and Language · Computer Science 2025-03-26 Meiquan Dong , Haoran Liu , Yan Huang , Zixuan Feng , Jianhong Tang , Ruoxi Wang

Advances in bio-technology have made available massive amounts of functional, structural and genomic data for many biological sequences. This increased availability of heterogeneous biological data has resulted in biological applications…

Computational Engineering, Finance, and Science · Computer Science 2013-02-26 Srikrishnan Divakaran , Arpit Mithal , Namit Jain

There is a widespread need for statistical methods that can analyze high-dimensional datasets with- out imposing restrictive or opaque modeling assumptions. This paper describes a domain-general data analysis method called CrossCat.…

Artificial Intelligence · Computer Science 2015-12-07 Vikash Mansinghka , Patrick Shafto , Eric Jonas , Cap Petschulat , Max Gasner , Joshua B. Tenenbaum

Federated fine-tuning of pre-trained Large Language Models (LLMs) enables task-specific adaptation across diverse datasets while preserving privacy. However, challenges such as high computational and memory demands, heterogeneous client…

Machine Learning · Computer Science 2025-05-19 Yang Su , Na Yan , Yansha Deng , Mischa Dohler , Robert Schober

Diffusion models have shown remarkable performance in image synthesis by progressively estimating a smooth transition from a Gaussian distribution of noise to a real image. Unfortunately, their practical deployment is limited by slow…

Machine Learning · Computer Science 2026-03-03 Dung Anh Hoang , Cuong Pham anh Trung Le , Jianfei Cai , Thanh-Toan Do

Phylogenetic tree reconstruction is traditionally based on multiple sequence alignments (MSAs) and heavily depends on the validity of this information bottleneck. With increasing sequence divergence, the quality of MSAs decays quickly.…

Populations and Evolution · Quantitative Biology 2011-01-11 Roland F. Schwarz , William Fletcher , Frank Förster , Benjamin Merget , Matthias Wolf , Jörg Schultz , Florian Markowetz

The problem of reconstructing evolutionary trees or phylogenies is of great interest in computational biology. A popular model for this problem assumes that we are given the set of leaves (current species) of an unknown binary tree and the…

Data Structures and Algorithms · Computer Science 2022-06-16 Eshwar Ram Arunachaleswaran , Anindya De , Sampath Kannan

This paper examines the quantization methods used in large-scale data analysis models and their hyperparameter choices. The recent surge in data analysis scale has significantly increased computational resource requirements. To address…

Machine Learning · Statistics 2024-01-31 Shuhei Kashiwamura , Ayaka Sakata , Masaaki Imaizumi

In this work, we consider the identifiability assumption of Gaussian linear structural equation models (SEMs) in which each variable is determined by a linear function of its parents plus normally distributed error. It has been shown that…

Machine Learning · Statistics 2019-10-22 Gunwoong Park , Younghwan Kim

Quantization has emerged as one of the most prevalent approaches to compress and accelerate neural networks. Recently, data-free quantization has been widely studied as a practical and promising solution. It synthesizes data for calibrating…

Computer Vision and Pattern Recognition · Computer Science 2021-12-03 Xiangguo Zhang , Haotong Qin , Yifu Ding , Ruihao Gong , Qinghua Yan , Renshuai Tao , Yuhang Li , Fengwei Yu , Xianglong Liu

Network alignment (NA) compares networks with the goal of finding a node mapping that uncovers highly similar (conserved) network regions. Existing NA methods are homogeneous, i.e., they can deal only with networks containing nodes and…

Molecular Networks · Quantitative Biology 2018-03-30 Shawn Gu , John Johnson , Fazle E. Faisal , Tijana Milenkovic

Randomization, as a key technique in clinical trials, can eliminate sources of bias and produce comparable treatment groups. In randomized experiments, the treatment effect is a parameter of general interest. Researchers have explored the…

Methodology · Statistics 2023-12-05 Fuyi Tu , Wei Ma , Hanzhong Liu